TPP-paclitaxel

TPP-paclitaxel refers to the conjugate of paclitaxel, a commonly used chemotherapy drug, with TPP (triphenylphosphonium) as a targeting moiety.The selective accumulation of TPP-paclitaxel in mitochondria allows for increased drug concentration at the site of action, enhancing its effectiveness and reducing systemic toxicity. This targeted delivery approach has shown promise in preclinical studies for improving the anti-cancer activity of paclitaxel.

msds of TPP-paclitaxel