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Catalog	name	Description	price
R-R-4852	COF-367-Cu	COF-367-Cu/Covalent Organic Framework-367-Cu refers to a specific type of Covalent Organic Framework (COF) that incorporates copper (Cu) atoms into its structure. COF-367 itself is a well-known COF characterized by its unique properties and applications.COF-367 is typically composed of organic building blocks that are linked together through strong covalent bonds, forming a porous and crystalline structure. The introduction of copper (Cu) atoms into this framework can enhance certain properties or introduce new functionalities due to the interaction of copper with the organic components.The incorporation of copper in COF-367-Cu can lead to improved catalytic properties, enhanced stability, or modified electronic properties compared to the non-metalated version of the COF. This can expand the potential applications of COF-367-Cu in areas such as catalysis, gas storage, sensing, or as a platform for controlled release of molecules.	price>
R-C-3183	Bufalin CAS:465-21-4	Bufalin(BF)is a potent inhibitor of steroid receptor coactivator SRC-3,SRC-1 and Na+/K+-ATPase. Bufalin binds to the subunit α1,α2 and α3 of Na+/K+-ATPase with Kd of 42.5 nM, 45 nM and 40 nM, respectively.	price>
R-R-4853	Gemcitabine elaidate hydrochloride CAS No.2918768-08-6	Gemcitabine elaidate (CP-4126) hydrochloride/CAS No.2918768-08-6 is lipophilic pro-agent of Gemcitabine. Gemcitabine elaidate hydrochloride is converted to Gemcitabine by esterases in order to be phosphorylated. Gemcitabine elaidate hydrochloride exhibits anti-tumor activity.	price>
R-C-3184	PPQ-102 CAS:931706-15-9	PPQ-102(CFTR Inhibitor IV)is a potent inhibitor of CFTR.PPQ-102 can completely inhibit CFTR chloride current with IC50 of ~90nM.	price>
R-R-4854	Rabacfosadine CAS No.859209-74-8	Rabacfosadine (GS-9219)/CAS No.859209-74-8, a novel proagent of the nucleotide analogue PMEG, is designed as a cytotoxic agent that preferentially targets lymphoid cells.	price>
R-C-3185	KM 11060 CAS:774549-97-2	KM 11060 is a small molecule that corrects the processing of cystic fibrosis transmembrane conductance regulator (CFTR) proteins bearing the F508 deletion (F508del) mutation carried by 90% of cystic fibrosis patients.KM 11060 corrects F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma membrane (~75%) and Inhibits PDE5 activity.	price>
R-R-4855	5-(Hydroxymethyl)cytidine CAS No.19235-17-7	5-(Hydroxymethyl)cytidine/CAS No.19235-17-7 is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.	price>
R-C-3186	GLPG2451 CAS:2055015-61-5	GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM.	price>
R-R-4856	Valopicitabine dihydrochloride CAS No.640725-71-9	Valopicitabine (NM283) dihydrochloride/CAS No.640725-71-9 is a nucleoside analog and the orally bioavailable proagent of the potent anti-HCV agent 2-C-methylcytidine (NM107). NM107competitively inhibits NS5B polymerase, causing chain termination.	price>
R-C-3187	Caldaret (MCC-135) CAS:133804-44-1	Caldaret is an intracellular Ca2+ handling modulator that acts through reverse mode Na+/Ca2+ exchanger inhibition.	price>
R-R-4857	Adenosine-d2 CAS No.82741-17-1	Adenosine-d2/CAS No.82741-17-1 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio.	price>
R-C-3188	TTA-Q6 CAS:910484-28-5	TTA-Q6 is a selective T-type Ca2+ channel antagonist, which can be used in the research of neurological disease.	price>
R-R-4858	3-O-Methylguanosine CAS No.10300-27-3	3-O-Methylguanosine/CAS No.10300-27-3 is a methylated nucleoside analogs and a RNA chain terminator. 3-O-methylguanosine can inhibit early virus-specific RNA synthesis.	price>
R-C-3189	GV-58 CAS:1402821-41-3	GV-58 is a potent, selective N- and P/Q-type Ca2+ channels agonist with EC50 of 7.21/8.81 uM for N-type/P-Q-type Ca2+ channel; 20-fold less potent CDK inhibitor activity.	price>
R-R-4859	3-Deoxyuridine-5-triphosphate trisodium	3-Deoxyuridine-5-triphosphate trisodium (3-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3-Deoxyuridine-5-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM.	price>
R-C-3190	Isradipine (Dynacirc) CAS:75695-93-1	Isradipine(PN 200-110)is a potent and selective L-type voltage-gated calcium channel blocker,used to treat high blood pressure.	price>
R-R-4860	2-O,4-C-Methylenecytidine CAS No.206055-69-8	2-O,4-C-Methylenecytidine (LNA-C(Bz))/CAS No.206055-69-8 is a bicyclic nucleoside analogue with fixed N-type conformation. 2-O,4-C-Methylenecytidine can be used to synthesize oligonucleotides. 2-O,4-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands.	price>
R-C-3191	Dantrolene CAS: 7261-97-4	Dantrolene sodium is a muscle relaxant that acts by abolishing excitation-contraction coupling in muscle cells, probably by action on the ryanodine receptor.	price>
R-R-4861	Adenosine-13C10,15N5 CAS No.202406-75-5	Adenosine-13C10,15N5/CAS No.202406-75-5 is the 13C and 15N labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.	price>
R-C-3192	Atagabalin CAS:223445-75-8	Atagabalin is related to gabapentin, which similarly binds to the α2δ calcium channels (1 and 2).	price>

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