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Catalog	name	Description	price
R-R-4778	Werner syndrome RecQ helicase-IN-2 CAS No.2869954-51-6	Werner syndrome RecQ helicase-IN-2 (example 57)/CAS No.2869954-51-6 is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and can be used in cancer research.	price>
R-C-3109	SMER3 CAS:67200-34-4	SMER3 is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase(SCFMet30)in vitro and in vivo. Induces the expression of MET genes;blocks cell proliferation.	price>
R-R-4779	3-Isomangostin CAS No.19275-46-8	3-Isomangostin/CAS No.19275-46-8, extracted from Garciniamangostana.L. shell, is a potent MutT homologue 1 (MTH1) inhibitor with an IC50 value of 52 nM. 3-Isomangostin would be an attractive chemical tool for the development of anticancer agents.	price>
R-R-4780	Risdiplam-d4	Risdiplam-d4 is deuterium labeled Risdiplam. Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels.	price>
R-C-3111	SJB3-019A CAS: 2070015-29-9	SJB3-019A,also known as SJB 019, is a USP1 inhibitor.	price>
R-R-4781	5-Iminodaunorubicin hydrochloride CAS No.67324-99-6	5-Iminodaunorubicin hydrochloride/CAS No.67324-99-6 is a quinone-modified anthracycline that retains antitumor activity. 5-Iminodaunorubicin hydrochloride produces protein-concealed DNA strand breaks in cancer cells.	price>
R-C-3112	DUBs-IN-1 CAS:924296-18-4	DUBs-IN-1 is a potent deubiquitinase enzyme inhibitor with IC50s of 18 uM/0.71 uM for USP7/USP8 respectively.	price>
R-R-4782	Saccharin 1-methylimidazole CAS No.482333-74-4	Saccharin 1-methylimidazole/CAS No.482333-74-4 is an activator for DNA/RNA Synthesis.	price>
R-C-3113	DUBs-IN-3 CAS：924296-17-3	DUBs-IN-3 is a potent deubiquitinase enzyme inhibitor with IC50s of 3.1uM for USP8;>30 fold selectivity over USP7 (IC50>100uM).	price>
R-R-4783	Cytidine-5-triphosphate-d14 disodium	Cytidine-5-triphosphate-d14 (disodium) is the deuterium labeled Cytidine-5-triphosphate. Cytidine 5-triphosphate (Cytidine triphosphate;5-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5-triphosphate from uridine 5-triphosphate (UTP). Cytidine 5-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii.	price>
R-C-3114	GNE-6640 CAS：2009273-67-8	GNE-6640 is a selective and non-covalent inhibitor of ubiquitin epecific peptidase 7 (USP7), with IC50 values of 0.75 μM,0.43 μM,20.3μM and 0.23μM for full length USP7, USP7 catalytic domain, full length USP43 and Ub-MDM2,respectively.	price>
R-R-4784	EFdA-TP tetrasodium CAS No.2883783-00-2	EFdA-TP tetrasodium/CAS No.2883783-00-2 is a potent nucleoside reverse transcriptase (RT) inhibitor. EFdA-TP tetrasodium inhibits RT-catalyzed DNA synthesis as an effective immediate or delayed chain terminator (ICT or DCT). EFdA-TP tetrasodium inhibits HIV-1 RT with multiple mechanisms. EFdA-TP (tetrasodium) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-C-3115	DUBs-IN-2 CAS：924296-19-5	DUBs-IN-2 is a potent deubiquitinase enzyme inhibitor with IC50s of 7.2uM/0.93uM for USP7/USP8 respectively.	price>
R-R-4785	8-NH2-ATP tetrasodium CAS No.35892-97-8	8-NH2-ATP tetrasodium/CAS No.35892-97-8, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado tetrasodium induces apoptosis-related cleavage of poly (ADP-ribose) polymerase.	price>
R-C-3116	HBX 41108 CAS：924296-39-9	HBX 41108 is an inhibitor of ubiquitin-specific protease (USP)7 activity(IC50=424nM).	price>
R-R-4786	RNase L-IN-1 trihydrochloride	RNase L-IN-1 (compound 17a) trihydrochloride is an inhibitor of RNase L or ribonuclease L. RNase L degrades RNA to prevent viral replication and mediates innate immune responses and inflammation.	price>
R-C-3117	GNE-490 CAS：1033739-92-2	GNE-490 is a highly selective pan-PI3K inhibitor that demonstrates selectivity over mTOR.	price>
R-R-4787	Enoxacin-d8 hydrochloride	Enoxacin-d8 (hydrochloride) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing.	price>
R-C-3118	GNE-9605 CAS：1536200-31-3	GNE-9605 is a highly potent and selective leucine-rich repeat kinase 2 (LRRK2)inhibitor with Ki and IC50 of 2 nM and 19 nM,respectively.	price>
R-R-4788	hDHODH-IN-3 CAS No.1644156-80-8	hDHODH-IN-3 (compound 21d)/CAS No.1644156-80-8 is a human dihydroorotate dehydrogenase (HsDHODH) inhibitor, inhibits measles virus replication with a pMIC50 value of 8.6.	price>

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