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| Catalog | name | Description | price |
|---|---|---|---|
| R-R-4624 | L82 CAS No.329227-30-7 | L82/CAS No.329227-30-7 is a selective and uncompetitive DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM). L82 shows anti-proliferative activity to breast cancer cells | price> |
| R-C-2955 | Oligoarginine-TAMRA Labeled | RuixiBiotechCo.Ltd sells research regeats related to nano targeted drug delivery system, including synthetic phospholipid, polyethylene glycol derivatives, block copolymers, gold nanoparticles, magnetic nanoparticles and fluorescent dyes. | price> |
| R-R-4625 | COH29 CAS No.1190932-38-7 | COH29 (RNR Inhibitor COH29)/CAS No.1190932-38-7 is a potent ribonucleotide reductase (RNR) inhibitor with anticancer activity. COH29 inhibits α and β subunit of RNR with IC50s of 16 μM. | price> |
| R-R-4626 | L189 CAS No.64232-83-3 | L189/CAS No.64232-83-3 is a DNA ligase inhibitor. L189 has inhibition effect for DNA Ligase I, III and IV with IC50 values of 5 μM, 9 μM and 5 μM, respectively. L189 has no cytotoxicity and individually increase cell death. L189 can be used for the research of cancer. | price> |
| R-C-2958 | PLA-PEOz-SH | Poly(D,L-lactide)-Poly(2-ethyl-2-oxazoline)is an amphiphilic AB block copolymer,it can be used to prepare PH responsivemicelle for drug delivery,PLA can choose DLLA or LLA.It is a pH responsive amphiphilic copolymer product | price> |
| R-R-4627 | APE1-IN-1 CAS No.524708-03-0 | APE1-IN-1/CAS No.524708-03-0 is a potent and blood-brain barrier (BBB) penetrant apurinic/apyrimidinic (AP) endonuclease 1 (APE1) inhibitor with an IC50 value of 2 μM. APE1-IN-1 can potentiate the cytotoxicity of the alkylating agents Methylmethane sulfonate and Temozolomide (HY-17364) to cancer cells. | price> |
| R-R-4628 | Galidesivir hydrochloride CAS No.222631-44-9 | Galidesivir (BCX4430) hydrochloride/CAS No.222631-44-9, an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir hydrochloride is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir hydrochloride inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM. | price> |
| R-C-2959 | PLGA-PEOz-MAL | Poly(L-lactide-co-glycolide)-Poly(2-ethyl-2-oxazoline)is an amphiphilic AB block copolymer,it can be used to prepare PH responsivemicelle for drug delivery, LA:GA:75:25/50:50. | price> |
| R-R-4629 | Bractoppin CAS No.2290527-07-8 | Bractoppin/CAS No.2290527-07-8 is a potent and selective agent-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem(t) BRCT domain (binding IC50: 74 nM). Bractoppin diminishes BRCA1 recruitment to DNA breaks, in turn suppressing damage-induced G2 arrest and assembly of the recombinase, RAD51. Bractoppin preferentially inhibits BRCA1 tBRCT-dependent steps in the DNA damage response. | price> |
| R-C-2960 | DSPE-TK-PEOz | DSPE(1,2-distearyl-sn-glycerin-3-phosphate ethanolamine) is a saturated 18 carbon phospholipid, which is commonly used in the synthesis of liposomes. Polyethylene glycol (PEG)-coupled DSPE is hydrophilic and can be used for drug delivery,gene transfection and biomolecular modification. At present, the mainly include synthetic phospholipids, PEG derivatives, block copolymers, gold nanoparticles, magnetic nanoparticles, mesoporous silica, reactive fluorescent dyes, fluorescent quantum dots, click chemistry and macrocyclic ligands. | price> |
| R-R-4630 | Lapachol CAS No.84-79-7 | Lapachol/CAS No.84-79-7, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity. | price> |
| R-C-2961 | 5-(4-hydroxyphenyl)-10,15,20-(4-methylphenyl) porphine | Porphyrin is a complex nitrogen-containing compound based on the structure of four pyrrole nuclei closed into ten J six rings. It is changed from animal and plant pigments (chlorophyll or heme). These pigments contain pyrrole nuclei. It mainly exists in the form of metal complexes (vanadium, nickel, iron, copper, cobalt, zinc, etc.) and they are very stable | price> |
| R-R-4631 | DHX9-IN-1 CAS No.2973747-89-4 | DHX9-IN-1 (example 160)/CAS No.2973747-89-4 is an inhibitor of ATP-dependent RNA helicase A (DHX9), with the IC50 of 9.45 nM that has antitumor activity. | price> |
| R-C-2962 | Mp-a08 CAS:219832-49-2 | Porphyrin is a complex nitrogen-containing compound based on the structure of four pyrrole nuclei closed into ten J six rings.It is changed from animal and plant pigments (chlorophyll or heme).These pigments contain pyrrole nuclei.It mainly exists in the form of metal complexes (vanadium, nickel, iron, copper, cobalt, zinc, etc.) and they are very stable. | price> |
| R-R-4632 | Dasabuvir CAS No.1132935-63-7 | Dasabuvir (ABT-333)/CAS No.1132935-63-7 is a nonnucleoside hepatitis C virus (HCV) polymerase inhibitor. Dasabuvir inhibits RNA-dependent RNA polymerase encoded by the HCV NS5B gene. Dasabuvir inhibits genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC50 values of 7.7 and 1.8 nM, respectively. | price> |
| R-C-2963 | 5,10,15,20-Tetrakis(3,5-dihydroxyphenyl)porphyrin cas 145764-54-1 | Porphyrin is a complex nitrogen-containing compound based on the structure of four pyrrole nuclei closed into ten J six rings. It is changed from animal and plant pigments (chlorophyll or heme).These pigments contain pyrrole nuclei. It mainly exists in the form of metal complexes (vanadium, nickel, iron, copper, cobalt, zinc, etc.) and they are very stable4634. | price> |
| R-R-4633 | Pyrazofurin CAS No.30868-30-5 | Pyrazofurin/CAS No.30868-30-5, a pyrimidine nucleoside analogue with antineoplastic activity, inhibits cell proliferation and DNA synthesis in cells by inhibiting uridine 5-phosphate (UMP) synthase. Pyrazofurin is an active, sensitive orotate-phosphoribosyltransferase inhibitor with IC50s between 0.06-0.37 µM in the three squamous cell carcinoma (SCC) cell lines Hep-2, HNSCC-14B and HNSCC-14C. | price> |
| R-C-2964 | 5,10,15,20-Tetrakis(3,5-dimethoxyphenyl )-21H,23H-porphyrin Cas:74684-34-7 | Porphyrin is a complex nitrogen-containing compound based on the structure of four pyrrole nuclei closed into ten J six rings. It is changed from animal and plant pigments (chlorophyll or heme). These pigments contain pyrrole nuclei. It mainly exists in the form of metal complexes (vanadium, nickel, iron, copper, cobalt, zinc, etc.) and they are very stable. | price> |
| R-R-4634 | ccc_R08 CAS No.2919019-72-8 | ccc_R08/CAS No.2919019-72-8 is a non-cytotoxic and orally active cccDNA inhibitor that reduces cccDNA levels in the liver of HBV-infected mice. ccc_R08 can be used in the study of HBV virus (hepatitis B virus) infection. | price> |
| R-C-2965 | SB-269970 | SB269970 is a potent and selective 5-HT7 receptor antagonist. | price> |

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