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Catalog	name	Description	price
R-R-4706	Brr2-IN-3 CAS No.2104030-82-0	Brr2-IN-3/CAS No.2104030-82-0 is a potent and selective Brr2 helicase allosteric Inhibitor. Brr2-IN-3 inhibits helicase activity in dose-dependent manner with an IC50 value of 1.3 μM.	price>
R-R-4707	UNC9512 CAS No.3032393-24-8	UNC9512/CAS No.3032393-24-8 is a potent methyl-lysine reader p53 binding protein 1 (53BP1) antagonist. UNC9512 can be used to study the role of 53BP1 in DNA repair, gene editing and tumorigenesis.	price>
R-R-4708	CeMMEC13 CAS No.1790895-25-8	CeMMEC13/CAS No.1790895-25-8 is a potent inhibitor of TAF1 (2) bromodomain, with an IC50 of 2.1 μM.	price>
R-R-4709	Antipain dihydrochloride CAS No.37682-72-7	Antipain dihydrochloride/CAS No.37682-72-7 is a protease inhibitor isolated from Actinomycetes. Antipain dihydrochloride inhibits N-methyl-N-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain dihydrochloride restricts uterine DNA synthesis and function in mice.	price>
R-C-3040	Duvelisib (IPI-145) CAS：1201438-56-3	Duvelisib (IPI-145, INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM in cell-free assays, highly selective for PI3K δ/γ than other protein kinases.	price>
R-R-4710	CM03 CAS No.2101208-44-8	CM03/CAS No.2101208-44-8 is a potent DNA G-quadruplexes (G4s) ligand. CM03 can stabilise G4s, downregulating more G4-containing genes as well as increasing incidence of double-strand break events (DSBs) due to torsional strain on DNA and chromatin structure. CM03 has selective potency for pancreatic cancer cells.	price>
R-C-3041	GSK1059615 CAS：958852-01-2	GSK1059615 is a potent, ATP-competitive inhibitor of PI 3-kinase alpha (PI3Kα) with IC50 of 2 nM. GSK1059615 is also a novel inhibitor of PI3Kβ, PI3Kδ, PI3Kγ and mTOR with IC50 of 0.6 nM, 2 nM, 5 nM and 12 nM, respectively.	price>
R-R-4711	NSAH CAS No.1099592-35-4	NSAH/CAS No.1099592-35-4 is a reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor, with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively.	price>
R-C-3042	PIK-90 CAS：677338-12-4	PIK-90 is a PI3Kα/γ/δ inhibitor with IC50 of 11 nM/18 nM/58 nM, respectively, less potent to PI3Kβ.	price>
R-R-4712	Sorivudine CAS No.77181-69-2	Sorivudine (BV-araU)/CAS No.77181-69-2 is an orally active synthetic pyrimidine nucleoside antimetabolite agent. Sorivudine derives its antiviral activity from selective conversion by a specific thymidine kinase present in certain DNA viruses to nucleotides, which can in turn interfere with viral DNA synthesis.	price>
R-C-3043	TG100-115 CAS：677297-51-7	TG100-115, inhibited PI3K γ and -δ(IC50 values of 83 and 235 nM, respectively), whereas both PI3Kα and -β were relatively unaffected (IC50 values>1 μM). As a gauge of general specificity, TG100-115 was also assayed against a 133 protein kinase panel, none of which was inhibited at IC50 values <1 μM.	price>
R-R-4713	N-Nitrosodiethylamine-d10 CAS No.1219794-54-3	N-Nitrosodiethylamine-d10/CAS No.1219794-54-3 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.	price>
R-C-3044	ZSTK474 CAS：475110-96-4	ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3 kinase isoforms.	price>
R-C-5834	DSPE-polyethylene glycol550-GGGGK(TAMRA)TILVSRSTQTGRRRRRRRR	DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is a lipid molecule that can be incorporated into lipid bilayers, such as liposomes.It provides stability and structure to lipid-based nanostructures.PEG (polyethylene glycol) is a biocompatible and hydrophilic polymer that is often attached to lipids to improve the stability, circulation time, and biocompatibility of liposomes.TAMRA is a commonly used fluorescent dye that can be conjugated to peptides(TILVSRSTQTGRRRRRRRR)or other biomolecules for visualization purposes.The molecular weight of PEGs varies.	price>
R-R-4714	Nogalamycin CAS No.1404-15-5	Nogalamycin/CAS No.1404-15-5 is an anthracyclinone antibiotic. Nogalamycin is a potent antibiotic against Gram-positive bacteria, also has cytotoxicity against certain tumor cells. Nogalamycin is produced by Streptomyces nogalater var. Nogalater. Nogalamycin selectively inhibits RNA synthesis after binding to DNA template. Nogalamycin can be used for researching anticancer.	price>
R-C-3045	PIK-75 CAS：372196-77-5	PIK-75 HCl is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.	price>
R-R-4715	hDHODH-IN-4 CAS No.1644156-56-8	hDHODH-IN-4/CAS No.1644156-56-8 is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, with a pIC50 of 7.8 for human recombinant DHODH. hDHODH-IN-4 inhibits measles virus replication, with a pMIC50 of 8.8.	price>
R-C-3046	MTI-31 CAS：1567915-38-1	MTI-31 (LXI-15029) is a novel mTORC1/mTORC2 inhibitor with Kd of 0.2 nM in mTOR binding assays and displays >5,000-fold selectivity over PIK3CA, PIK3CB and PIK3G.	price>
R-R-4716	5-Methoxyflavone CAS No.42079-78-7	5-Methoxyflavone/CAS No.42079-78-7, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABAA receptors.	price>
R-C-3047	mTOR inhibitor-1 cas:468747-17-3	mTOR inhibitor-1 is a novel inhibitor of mTOR pathway. mTOR inhibitor-1 suppress cells proliferation and induces autophagy.	price>

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