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Catalog | name | Description | price |
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R-C-3112 | DUBs-IN-1 CAS:924296-18-4 | DUBs-IN-1 is a potent deubiquitinase enzyme inhibitor with IC50s of 18 uM/0.71 uM for USP7/USP8 respectively. | price> |
R-R-4782 | Saccharin 1-methylimidazole CAS No.482333-74-4 | Saccharin 1-methylimidazole/CAS No.482333-74-4 is an activator for DNA/RNA Synthesis. | price> |
R-C-3113 | DUBs-IN-3 CAS:924296-17-3 | DUBs-IN-3 is a potent deubiquitinase enzyme inhibitor with IC50s of 3.1uM for USP8;>30 fold selectivity over USP7 (IC50>100uM). | price> |
R-R-4783 | Cytidine-5-triphosphate-d14 disodium | Cytidine-5-triphosphate-d14 (disodium) is the deuterium labeled Cytidine-5-triphosphate. Cytidine 5-triphosphate (Cytidine triphosphate;5-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5-triphosphate from uridine 5-triphosphate (UTP). Cytidine 5-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii. | price> |
R-C-3114 | GNE-6640 CAS:2009273-67-8 | GNE-6640 is a selective and non-covalent inhibitor of ubiquitin epecific peptidase 7 (USP7), with IC50 values of 0.75 μM,0.43 μM,20.3μM and 0.23μM for full length USP7, USP7 catalytic domain, full length USP43 and Ub-MDM2,respectively. | price> |
R-R-4784 | EFdA-TP tetrasodium CAS No.2883783-00-2 | EFdA-TP tetrasodium/CAS No.2883783-00-2 is a potent nucleoside reverse transcriptase (RT) inhibitor. EFdA-TP tetrasodium inhibits RT-catalyzed DNA synthesis as an effective immediate or delayed chain terminator (ICT or DCT). EFdA-TP tetrasodium inhibits HIV-1 RT with multiple mechanisms. EFdA-TP (tetrasodium) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | price> |
R-C-3115 | DUBs-IN-2 CAS:924296-19-5 | DUBs-IN-2 is a potent deubiquitinase enzyme inhibitor with IC50s of 7.2uM/0.93uM for USP7/USP8 respectively. | price> |
R-R-4785 | 8-NH2-ATP tetrasodium CAS No.35892-97-8 | 8-NH2-ATP tetrasodium/CAS No.35892-97-8, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado tetrasodium induces apoptosis-related cleavage of poly (ADP-ribose) polymerase. | price> |
R-C-3116 | HBX 41108 CAS:924296-39-9 | HBX 41108 is an inhibitor of ubiquitin-specific protease (USP)7 activity(IC50=424nM). | price> |
R-R-4786 | RNase L-IN-1 trihydrochloride | RNase L-IN-1 (compound 17a) trihydrochloride is an inhibitor of RNase L or ribonuclease L. RNase L degrades RNA to prevent viral replication and mediates innate immune responses and inflammation. | price> |
R-C-3117 | GNE-490 CAS:1033739-92-2 | GNE-490 is a highly selective pan-PI3K inhibitor that demonstrates selectivity over mTOR. | price> |
R-R-4787 | Enoxacin-d8 hydrochloride | Enoxacin-d8 (hydrochloride) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing. | price> |
R-C-3118 | GNE-9605 CAS:1536200-31-3 | GNE-9605 is a highly potent and selective leucine-rich repeat kinase 2 (LRRK2)inhibitor with Ki and IC50 of 2 nM and 19 nM,respectively. | price> |
R-R-4788 | hDHODH-IN-3 CAS No.1644156-80-8 | hDHODH-IN-3 (compound 21d)/CAS No.1644156-80-8 is a human dihydroorotate dehydrogenase (HsDHODH) inhibitor, inhibits measles virus replication with a pMIC50 value of 8.6. | price> |
R-C-3119 | Vialinin A CAS:858134-23-3 | Vialinin A is a terphenyl compound originally isolated from the fungi T. terrestris and T.vialis. | price> |
R-R-4789 | Thymidine-15N2 | Thymidine-15N2 is the 15N labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. | price> |
R-C-3120 | MSC1094308 CAS:2219320-08-6 | MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase human ubiquitin-directed unfoldase(VCP)/p97 and the type I AAA ATPase VPS4B,with IC50 values of 0.71μM and 7.2μM for VPS4B and p97,respectively. | price> |
R-R-4790 | Mitonafide CAS No.54824-17-8 | Mitonafide (NSC 300288)/CAS No.54824-17-8 is a cytostatic agent. Mitonafide binds to double-stranded DNA through intercalation, and inhibits DNA and RNA synthesis. Mitonafide is an antitumor agent that can be used in the research of cancers, such as non-small cell lung cancer (NSCLC), leukemia. | price> |
R-C-3121 | NMS-859 CAS:1449236-96-7 | NMS-859 is a potent,covalent VCP(p97)inhibitor,with IC50s of 0.37 and 0.36μM for wild-type VCP in the presence of 60μM and 1 mM ATP in cells,respectively. | price> |
R-R-4791 | Werner syndrome RecQ helicase-IN-4 CAS No.2869954-53-8 | Werner syndrome RecQ helicase-IN-4/CAS No.2869954-53-8 is a potent and orally active werner syndrome recQ helicase (WRN) inhibitor with an IC50 value of 0.06 µM. Werner syndrome RecQ helicase-IN-4 shows antiproliferative activity. Werner syndrome RecQ helicase-IN-4 shows anticancer activity. | price> |