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Catalog | name | Description | price |
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R-R-4663 | T2AA CAS No.1380782-27-3 | T2AA/CAS No.1380782-27-3 is a monoubiquitinated proliferating cell nuclear antigen (PCNA) inhibitor that prevents DNA repair, increases double-strand break (DSB) formation and promotes necroptosis and cell cycle arrest in G1 phase. | price> |
R-C-2994 | GDC-0077 CAS:2060571-02-8 | GDC-0077 is a potent and selective PI3K inhibitor. GDC-0077 blocks an enzyme involved in cancer growth called PI3K. GDC0077 binds to and inhibits various members of the PI3K family, including activating mutations in the catalytic alpha isoform PIK3CA. PI3K inhibition prevents the activation of the PI3K-mediated signaling pathway and results in the inhibition of growth and survival of PI3K-overexpressing tumor cells.Only for scientific research, not for human body. | price> |
R-R-4664 | 1,1,1-Trifluoroethyl-PEG4-amine CAS: 1872433-72-1 | 1, 1, 1-Trifluoroethyl-PEG4-Amine/1,1,1-Trifluoroethyl-Polyethylene glycol 4-amine/CAS: 1872433-72-1 is a PEG linker with a trifluoroethyl and amine moiety. The amine can react with carboxylic acids, activated NHS esters and other carbonyl compounds. The hydrophilic PEG chain increases the water solubility of the compound in aqueous media. Reagent grade, for research purpose. | price> |
R-C-2995 | Parsaclisib (INCB050465) CAS:1426698-88-5 | Parsaclisib (INCB050465) is a potent and selective PI3Kδ inhibitor, with an IC50 of 1 nM at 1 mM ATP. Parsaclisib inhibits proliferation of several DLBCL and MCL cell lines in vitro (EC50 < 10 nM).Parsaclisib displays significant activity with IC50 values ranging from 0.2 to 2 nM in B and T cell proliferation assays.Only for scientific research, not for human body. | price> |
R-R-4665 | N-(2-Aminoethyl)-4-[3-(trifluoromethyl)-3H-diazin-3-yl]benzamide CAS:129476-77-3 | N-(2-Aminoethyl)-4-[3-(trifluoromethyl)-3H-diazin-3-yl]benzamide CAS:129476-77-3 is a small molecule drug that is composed of several functional groups. The N-(2-aminoethyl) group is a type of amine group that contains a nitrogen atom and is commonly used as a building block for the synthesis of other organic molecules. The 3-(trifluoromethyl)-3H-diazin-3-yl group is a heterocyclic aromatic compound that contains a nitrogen atom and three fluorine atoms. The benzamide group is another type of amide group that contains a nitrogen atom and is commonly used as a building block for the synthesis of other organic molecules.The combination of these functional groups in N-(2-Aminoethyl)-4-[3-(trifluoromethyl)-3H-diazin-3-yl]benzamide is designed to create a drug that can be used to target specific biological processes in the body. The 3-(trifluoromethyl)-3H-diazin-3-yl group, for example, is known to have significant activity against certain types of cancer cells, while the N-(2-aminoethyl) group can help to improve the solubility and stability of the drug in solution. | price> |
R-C-2996 | 740 Y-P cas:1236188-16-1 | 740 Y-P is a potent and cell permeable PI3K activator.Only for scientific research, not for human body. | price> |
R-R-4666 | 4-Azide-TFP-Amide-SS-Sulfo-NHS | Ruixi provides you with high-purity 4-Azide-TFP-Amide-SS-Sulfo-NHS which is a linker composed of aryl azide, cleavable disulfide bond and NHS ester, and the disulfide bond can be reduced agent cleavage, NHS esters react with amines, and fluorine helps stabilize the free-radical intermediate. | price> |
R-C-2997 | Fenoldopam CAS:67227-56-9 | Fenoldopam is used as an antihypertensive agent postoperatively,and also intravenously(IV)to treat a hypertensive crisis.Only for scientific research, not for human body. | price> |
R-R-4667 | Cyamemazine sulfoxide CAS No:13384-45-7 | Cyamemazine sulfoxide/10-[3-(Dimethylamino)-2-methylpropyl]-10H-phenothiazine-2-carbonitrile 5-oxide/CAS No:13384-45-7 is a histamine H1 receptor antagonist. It has been shown to have strong affinity for the serotonin 5-HT2C and dopamine D2 receptors, as well as the atrial 5-HT2A receptors. Cyamemazine sulfoxide has a low oral bioavailability of about 10% and is metabolized in the liver to cyamemazine and its active form, cyamemazine sulfoxide. Cyamemazine sulfoxide binds to serotonin 5-HT2C receptors with a high affinity, which leads to inhibition of serotonin release from nerve endings in the brain. This drug also inhibits dopamine release from nerve endings in the brain and has been shown to have cardiac effects on heart rate and contractility. | price> |
R-C-2998 | Adrenorphin CAS:88377-68-8 | Adrendorphin is an opioid octapeptide μ- Opioid receptor agonist with Ki value of 12 nm.Only for scientific research, not for human body. | price> |
R-C-4668 | Gallium arsenide-PEG750-DSPE | 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy] (sodium salt)It is a long circulating liposome membrane,formation of micelles in water dispersion,so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors. Suitable for the development of long circulating liposomes. | price> |
R-R-4668 | 2,4-Dideoxy-2,4-difluoro-D-glucose CAS No:38711-44-3 | 2,4-Dideoxy-2,4-difluoro-D-glucose/CAS No:38711-44-3 is a fluorinated glucose analog that has been synthesized to be used as an imaging agent for positron emission tomography (PET) and single photon emission computed tomography (SPECT). It is labeled with fluorine-18 and can be metabolically incorporated into the cellular glycolytic pathway. 2,4-Dideoxy-2,4-difluoro-D-glucose emits positrons that are detected by PET or SPECT cameras. The incorporation of 2,4-dideoxy-2,4-difluoro--D--glucose into the glycolytic pathway allows it to be used as a marker for positron emission tomography. | price> |
R-C-2999 | Trimidox cas:95933-74-7 | Trimidox (3.4.5-tri-hydroxybenzohydroxamidoxime) is a specific and patented ribonucleotide reductase (RNR) inhibitor.Only for scientific research, not for human body. | price> |
R-R-4669 | 2,4,5-Trimethoxyamphetamine CAS No;1083-09-6 | 2,4,5-Trimethoxyamphetamine (TMA)/CAS No;1083-09-6 is a psychoactive drug and psychedelic that belongs to the class of substituted amphetamines. It has high affinity for serotonergic 5-HT 1A receptors and moderate affinity for dopaminergic D 2 receptors. TMA also interacts with 5-HT 1A and 5-HT 2C serotonin receptors. TMA is used in humans as an adjunct to psychotherapy. It has a low potential for abuse, but can produce adverse reactions such as skin irritation or neurotoxicity. | price> |
R-C-3000 | Didox (NSC-324360) CAS:69839-83-4 | Didox(nsc-324360)is a synthetic ribonucleotide reductase (RR) inhibitor.Only for scientific research, not for human body. | price> |
R-R-4670 | JWH 019 5-hydroxyindole metabolite CAS No:1379604-70-2 | JWH 019/JWH 019 5-hydroxyindole metabolite/CAS No:1379604-70-2 is a synthetic cannabinoid that has been shown to be an analog of Δ9-tetrahydrocannabinol (THC). In animal models, JWH 019 has been shown to have similar effects on the central nervous system to THC. It is metabolized in human urine and remains detectable for longer periods of time than THC. The detection of this drug in urine samples can be accomplished using analytical methods such as xlr-11, fluorine, and monohydroxylation. | price> |
R-C-3001 | Rutaecarpine CAS:84-26-4 | Rutaecarpine, also known as NSC 258317, is a quinazolinone alkaloid originally isolated from E. rutaecarpa that has diverse biological activities. Only for scientific research,not for human body. | price> |
R-R-4671 | 1-Trityl-4-vinyl-1H-imidazole CAS No:86803-29-4 | 1-Trityl-4-vinyl-1H-imidazole/CAS No:86803-29-4 is a heterocycle that has been shown to be reactive with boronic acid, oxidant, and hydrogen fluoride. It has been shown to react with fluorine containing compounds from the fluoroalkyl group. This molecule is also capable of undergoing pericyclic reactions and catalysis. 1-Trityl-4-vinyl-1H-imidazole has been shown to be functionalized with various substituents and can form complex molecules. This molecule has also been used as a precursor for synthesizing imidazole derivatives. | price> |
R-C-3002 | Luotonin A cas:205989-12-4 | Luotonin A binds to and stabilizes the topoisomerase I-DNA binary complex.Topoisomerase DNA complexes have been reported as the primary target of several important antitumor agents. Only for scientific research, not for human body. | price> |
R-R-4672 | JPH203 CAS No:1037592-40-7 | JPH203/O-[(5-Amino-2-phenyl-7-benzoxazolyl)methyl]-3,5-dichloro-L-tyrosine/CAS No:1037592-40-7 is a compound that has been shown to inhibit the growth of hypoxic tumor cells. It was found to induce apoptosis in tubule cells through a number of mechanisms, including the inhibition of cyclin D2 protein synthesis and the disruption of cellular signaling pathways. JPH203 is structurally similar to organic anion transporters (OATs), which are drug transporters in the body. This property may help it to cross the blood-brain barrier and reach tumors in the brain. JPH203 has also been shown to inhibit cancer cell proliferation and induce apoptosis in colorectal adenocarcinoma cells, as well as inhibiting tumor growth in animal models. | price> |