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Catalog	name	Description	price
R-C-3027	TGR-1202 (Umbralisib) CAS:1532533-67-7	Umbralisib (TGR-1202, Rp-5264), a novel, next generation PI3Kδ inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.2 & 24.3 nM, respectively.Only for scientific research, not for human body.	price>
R-R-4697	6-Fluoro-6-deoxy-D-galactose CAS No:4536-07-6	6-Fluoro-6-deoxy-D-galactose (FDG)/CAS No:4536-07-6 is a fluorinated sugar. FDG has been shown to inhibit the uptake of glucose by l1210 murine cells, as well as the transport of glucose into the cell. It also inhibited cell culture and enzyme activities in human liver tissue. The electron microscopic analysis of cytochalasin B and trifluoroacetic acid treated cells showed that FDG disrupts the microtubule network, leading to inhibition of cellular proliferation. FDG has also been found to inhibit the synthesis of DNA and RNA in L5178 murine lymphoma cells.	price>
R-C-3028	GDC-0326 CAS:1282514-88-8	GDC-0326 is a potent and selective inhibitor of PI3Kα with Ki value of 0.2 nM; remarkably selective over the other class I isoforms in enzymatic assays.Only for scientific research, not for human body.	price>
R-R-4698	1,3,5-Tri-O-acetyl-2-deoxy-2-fluoro-a-D-arabinofuranose CAS No:444586-86-1	1,3,5-Tri-O-acetyl-2-deoxy-2-fluoro-a-D-arabinofuranose/CAS No:444586-86-1 is a sugar that is modified with fluorine. It has been synthesized using the "click" reaction methodology and is available for custom synthesis. This synthetic sugar can be used in glycosylation reactions or as a monosaccharide or polysaccharide in complex carbohydrate click chemistry. This product is of high purity and can be modified with methyl groups or other functional groups to suit your needs.	price>
R-C-3029	acalisib (GS-9820) CAS:870281-34-8	Acalisib (GS-9820, CAL-120) is a highly selective and potent p110δ inhibitor (IC50 = 14 nM) with 114- to 400-fold selectivity over the other class I PI3K enzymes and no activity against Class II and III PI3K family members or other PI3K-related proteins including mTOR and DNA-PK.Only for scientific research, not for human body.	price>
R-R-4699	4-Chloromethyl-6,8-difluoroumbelliferyl b-D-galactopyranoside CAS No:215868-46-5	4-Chloromethyl-6,8-difluoroumbelliferyl b-D-galactopyranoside/CAS No:215868-46-5 is a compound commonly used in biochemical research as a fluorescent substrate for the detection of sugar hydrolase enzymes. This compound can be cleaved by enzymes such as Î²-galactosidase, releasing a fluorescent molecule that can be easily detected using fluorescence spectroscopy. The compound is a member of the family of umbelliferyl glycosides, which have been widely used in the study of various biochemical pathways for many years. The advantage of using this particular substrate is that the fluorescent product has a high quantum yield, which means it produces a strong signal for detection. This substrate has been used in a wide variety of applications, including the study of microbial physiology and in the development of diagnostic assays for detecting bacterial and fungal infections.	price>
R-C-3031	AMG 511 CAS:1253573-53-3	AMG 511 is a potent and selective pan class I PI3K inhibitor, capable of inhibiting PI3K signaling and inducing robust anti-proliferative effects via a G1 arrest in many tumor cell lines, with evidence of cell killing in a subset of lines.Only for scientific research, not for human body.	price>
R-R-4700	6,8-Difluoro-4-methylumbelliferyl b-D-glucopyranoside CAS:351009-26-2	6,8-Difluoro-4-methylumbelliferyl b-D-glucopyranoside/CAS:351009-26-2 is a versatile fluorogenic substrate suitable for the measurement of various glycosidase enzymes. Its unique structure allows for enhanced sensitivity and selectivity in enzyme assays, making it ideal for studying enzyme kinetics and screening of potential enzyme inhibitors.	price>
R-R-4701	6-Fluoro-3-indoxyl-beta-D-galactopyranoside CAS No:207727-11-5	6-Fluoro-3-indoxyl-beta-D-galactopyranoside/CAS No:207727-11-5 is a fluorescent chromogenic substrate that is commonly used for the detection and quantification of beta-galactosidase activity. When this substrate is hydrolyzed by beta-galactosidase, it produces a fluorescent blue product that can be easily detected and measured using a fluorometer or spectrophotometer. This substrate is often used in microbiology and molecular biology research to study gene expression and enzyme kinetics, and is also used in medical diagnostics as a marker for specific diseases and conditions.	price>
R-C-3032	AS-604850 CAS:648449-76-7	AS-604850 is a selective,ATP-competitive PI3Kγ inhibitor with IC50 of 250nM,over 80-fold selectivity for PI3Kγ than PI3Kδ/β, and 18-fold more selective for PI3Kγ than PI3Kα.Only for scientific research, not for human body.	price>
R-R-4702	4-Trifluoromethylumbelliferyl-b-D-galactopyranoside CAS No:117153-55-6	4-Trifluoromethylumbelliferyl β-D-galactopyranoside/4-Trifluoromethylumbelliferyl-beta-D-galactopyranoside/CAS No:117153-55-6 is a chromogenic substrate that can be used to detect the presence of β-glucuronidase and β-galactosidase in a variety of organisms. This compound has been shown to be useful for the detection of bacteria such as E. coli, Salmonella, and Listeria monocytogenes. 4TFU has been shown to hydrolyze at pH values between 5 and 8. The reaction starts with a color change from yellow to blue at pH 5, which changes again to green at pH 8. The equivalence point for this substrate is at pH 6.4, where it produces an orange color.	price>
R-R-4703	Trifluoroacetamidoethyl-SS-propionic NHS ester CAS: 2380318-60-3	Trifluoroacetamidoethyl-SS-propionic NHS ester/CAS: 2380318-60-3 is a cleavable linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The disulfide bond can be cleaved under reduction conditions. Reagent grade, for research purpose.	price>
R-R-4704	1,1,1-Trifluoroethyl-PEG5-alcohol CAS: 1807512-41-9	1,1,1-Trifluoroethyl-PEG5-alcohol/CAS: 1807512-41-9 is a PEG linker containing a trifluoroethyl and alcohol group. The trifluoroethyl group is used to react with lysine and other primary amine groups in proteins, antibody and other molecules and surfaces. The alcohol group can react to further derivatize the compound. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media.	price>
R-R-4705	Tris(2-(4,6-difuorophenyl)pyridine)iridium(III) CAS .387859-70-3	Tris(2-(4,6-difluorophenyl)pyridine)iridium(III)/Tris[2-(4,6-difluorophenyl)pyridinato-C2,N]iridium(III)/CAS .387859-70-3 is a coordination compound containing an iridium(III) ion coordinated with three ligands, each composed of a 2-(4,6-difluorophenyl)pyridine moiety. This compound is known for its luminescent properties and finds applications in organic light-emitting diodes (OLEDs) and other optoelectronic devices.The complex structure of the compound, with the iridium ion at its center and the three difluorophenylpyridine ligands surrounding it, contributes to its unique optical properties. The presence of the difluorophenyl groups on the ligands can influence the emission characteristics and efficiency of the compound, making it useful in the development of efficient light-emitting materials.	price>
R-R-4706	Brr2-IN-3 CAS No.2104030-82-0	Brr2-IN-3/CAS No.2104030-82-0 is a potent and selective Brr2 helicase allosteric Inhibitor. Brr2-IN-3 inhibits helicase activity in dose-dependent manner with an IC50 value of 1.3 μM.	price>
R-R-4707	UNC9512 CAS No.3032393-24-8	UNC9512/CAS No.3032393-24-8 is a potent methyl-lysine reader p53 binding protein 1 (53BP1) antagonist. UNC9512 can be used to study the role of 53BP1 in DNA repair, gene editing and tumorigenesis.	price>
R-R-4708	CeMMEC13 CAS No.1790895-25-8	CeMMEC13/CAS No.1790895-25-8 is a potent inhibitor of TAF1 (2) bromodomain, with an IC50 of 2.1 μM.	price>
R-R-4709	Antipain dihydrochloride CAS No.37682-72-7	Antipain dihydrochloride/CAS No.37682-72-7 is a protease inhibitor isolated from Actinomycetes. Antipain dihydrochloride inhibits N-methyl-N-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations. Antipain dihydrochloride restricts uterine DNA synthesis and function in mice.	price>
R-C-3040	Duvelisib (IPI-145) CAS：1201438-56-3	Duvelisib (IPI-145, INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM in cell-free assays, highly selective for PI3K δ/γ than other protein kinases.	price>
R-R-4710	CM03 CAS No.2101208-44-8	CM03/CAS No.2101208-44-8 is a potent DNA G-quadruplexes (G4s) ligand. CM03 can stabilise G4s, downregulating more G4-containing genes as well as increasing incidence of double-strand break events (DSBs) due to torsional strain on DNA and chromatin structure. CM03 has selective potency for pancreatic cancer cells.	price>

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