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R-C-2812 Firocoxib CAS:189954-96-9 Firocoxib is a non-steroidal anti-inflammatory drug of the COX-2 inhibitor class,currently approved for use in dogs and horses. price>
R-R-4512 Calicheamicin CAS No.108212-75-5 Calicheamicin/CAS No.108212-75-5, an antitumor antibiotic, is a cytotoxic agent that causes double-strand DNA breaks. Calicheamicin is a DNA synthesis inhibitor. Calicheamicin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. price>
R-C-2813 Bepotastine Besilate CAS:190786-44-8 Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist.Bepotastine besilate has the potential for allergic rhinitis,allergic conjunctivitis and urticaria/pruritus research. price>
R-R-4513 Lurbinectedin CAS No.497871-47-3 Lurbinectedin (PM01183)/CAS No.497871-47-3 is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively. price>
R-C-2814 LY 379268 CAS:191471-52-0 LY379268 is a potent,selective and brain-penetrant mGlu2/3R agonist with EC50 values of 2.69nM(mGlu2)and 4.48nM(mGlu3).LY379268 has no activity on human mGlu 1a,4a,5a or 7a receptors.LY379268 has antioxidant and neuroprotective effects. price>
R-R-4514 SG3199 CAS No.1595275-71-0 SG3199/CAS No.1595275-71-0 is a cytotoxic DNA minor groove interstrand crosslinking pyrrolobenzodiazepine (PBD) dimer. SG3199 is the released warhead component of the ADC payload Tesirine (SG3249). price>
R-R-4515 Tesirine CAS No.1595275-62-9 Tesirine (SG3249)/CAS No.1595275-62-9 is an antibody-drug conjugate (ADC) pyrrolobenzodiazepine (PBD) dimer payload. Tesirine combines potent antitumor activity with desirable physicochemical properties such as favorable hydrophobicity and improved conjugation characteristics. SG3199 (HY-101161) is the released warhead component of the ADC payload Tesirine. SG3199 retains picomolar activity in a panel of cancer cell lines. PBD dimers are highly efficient DNA minor groove cross-linking agents with potent cytotoxicity. price>
R-R-4516 Lomustine CAS No.13010-47-4 Lomustine (CCNU; NSC 79037)/CAS No.13010-47-4 is a DNA alkylating agent, with antitumor activity. price>
R-R-4517 Procarbazine Hydrochloride CAS No.366-70-1 Procarbazine Hydrochloride/CAS No.366-70-1 is an orally active alkylating agent, with anticancer activity. Procarbazine Hydrochloride can be used in Hodgkin disease research. price>
R-R-4518 Thio-TEPA CAS No.52-24-4 Thio-TEPA /CAS No.52-24-4 is a DNA alkylating agent, with antitumor activity. price>
R-C-2849 RS 127445 CAS:199864-87-4 RS-127445(MT500)is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4,exhibits >1000-fold selectivity against other 5-HT receptors. price>
R-R-4519 SJG-136 CAS No.232931-57-6 SJG-136/CAS No.232931-57-6 is a DNA cross-linking agent, with an XL50 of 45 nM for pBR322 DNA. SJG-136 has potent antitumor activity. price>
R-C-2850 DOPE-PDP Dope conjugated polyethylene glycol is a combination of phospholipids and polyethylene glycol,which has hydrophilicity and hydrophobicity. price>
R-R-4520 Duocarmycin TM CAS No.157922-77-5 Duocarmycin TM (CBI-TMI)/CAS No.157922-77-5 is a potent antitumor antibiotic. Duocarmycin TM induces a sequence-selective alkylation of duplex DNA. price>
R-C-2851 DSPE-PEG2K-KSKVGFLQLLFHKK(Biotin)-OH 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy](sodium salt)is a PEG-modified lipids.It is a long circulating liposome membrane,formation of micelles in water dispersion,the critical micelle concentration(CMC)ratio of surfactant is 102 times lower,so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups. price>
R-R-4521 Trioxsalen CAS No.3902-71-4 Trioxsalen (Trisoralen)/CAS No.3902-71-4, a psoralen derivative, is a photochemical DNA crosslinker. Trioxsalen only works after photoactivation with near ultraviolet light. Trioxsalen is a photosensitizer that can be used for the research of vitiligo and hand eczema. Trioxsalen is used for visualization of genomic interstrand cross-links localized by laser photoactivation. price>
R-C-2852 DSPE-PEG-HYD-DOX 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy] (sodium salt)is a PEG-modified lipids.so the drug stability is better, even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors.Suitable for the development of long circulating liposomes.It can connect peptides and other groups.Doxorubicin is an anti-tumor antibiotic,which can inhibit the synthesis of RNA and DNA.It has the strongest inhibitory effect on RNA and has a wide anti-tumor spectrum.It has an effect on a variety of tumors.It is a cycle nonspecific drug and can kill tumor cells in various growth cycles. price>
R-R-4522 KCC-07 CAS No.315702-75-1 KCC-07/CAS No.315702-75-1 is a potent, selective and brain-penetrant MBD2 (methyl-CpG-binding domain protein 2) inhibitor. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling. Anticancer activity. price>
R-C-2853 DSPE-PEG-Desthiobiotin Desthiobiotin is a single ring,sulfur-free biotin.It binds to streptomycin and has almost the same specificity,but its affinity is smaller than biotin (Kd = 1011 and 1015m).1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[(polyethylene glycol)-methoxy](sodium salt)is a PEG-modified lipids.so the drug stability is better,even by hemodilution,can maintain the integrity of the micelle particle,has certain targeting,easy accumulation in solid tumors. Suitable for the development of long circulating liposomes.It can connect peptides and other groups. price>
R-R-4523 Duocarmycin DM free base CAS No.1116745-06-2 Duocarmycin DM free base/CAS No.1116745-06-2, a DNA minor-groove alkylator, is an antibody agent conjugates (ADCs) toxin. Duocarmycin DM free base is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. price>