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Catalog	name	Description	price
R-C-2232	Loureirin A CAS：119425-89-7	Loureirin A is a flavonoid extracted from Dragon is Blood,can inhibit Akt phosphorylation,and has antiplatelet activity.	price>
R-R-3932	Bufuralol-d9 hydrochloride CAS No.1173023-51-2	Bufuralol-d9 (hydrochloride)/CAS No.1173023-51-2 is the deuterium labeled Bufuralol hydrochloride.	price>
R-C-2233	AT7867 CAS：857531-00-1	AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17nM/47nM and 85nM/20nM in cell-free assays,respectively;little activity outside the AGC kinase family.	price>
R-R-3933	Bisoprolol-d5 CAS No.1189881-87-5	Bisoprolol-d5/CAS No.1189881-87-5 is the deuterium labeled Bisoprolol. Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker. Bisoprolol has little activity on β2-receptor and has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research.	price>
R-C-2234	Triciribine (NSC 154020) CAS:35943-35-2	Triciribine(VQD-002)is a potent AKT inhibitor and a cell-permeable tricyclic nucleoside molecule with potential antineoplastic activity.Triciribine inhibits the phosphorylation,activation, and signalling of Akt-1,-2,and-3,which may result in the inhibition of Akt-expressing tumor cell proliferation.Akts are anti-apoptotic serine/theronine-specific protein kinases that phosphorylate and inactivate components of the apoptotic machinery,including Bcl-xL/Bcl-2-associated death promoter(BAD)and caspase 9.	price>
R-R-3934	Atomoxetine-d3 hydrochloride CAS No.1217776-38-9	Atomoxetine-d3 hydrochloride/CAS No.1217776-38-9 is the deuterium labeled Atomoxetine hydrochloride. Atomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively).	price>
R-C-2235	CCT128930 CAS： 885499-61-6	CCT128930 is a potent,ATP-competitive and selective inhibitor of Akt2 with IC50 of 6nM in a cell-free assay,28-fold greater selectivity for Akt2 than the closely related PKA kinase.CCT128930 induces cell cycle arrest,DNA damage,and autophagy independent of Akt inhibition.High dose of CCT128930 triggers cell apoptosis in HepG2 cells.	price>
R-R-3935	Doxazosin-d8 hydrochloride CAS No.1219803-95-8	Doxazosin-d8 (hydrochloride)/CAS No.1219803-95-8 is the deuterium labeled Doxazosin hydrochloride.	price>
R-C-2236	Miltefosine CAS：58066-85-6	Miltefosine(Hexadecylphosphocholine)inhibits PI3K/Akt activity with ED50 of 17.2μM and 8.1μM in carcinoma cell lines A431 and HeLa,first oral drug for Visceral leishmaniasis,effective against both promastigotes and amastigotes.	price>
R-R-3936	Celiprolol-d9 hydrochloride CAS No.1215535-20-8	Celiprolol-d9 (hydrochloride)/CAS No.1215535-20-8 is the deuterium labeled Celiprolol hydrochloride.	price>
R-C-2237	Honokiol (NSC 293100) CAS：35354-74-6	Honokiol is a lignan present in the cones,bark,and leaves of Magnolia grandiflora that has shown pro-apoptotic effects in melanoma,sarcoma,myeloma, leukemia,bladder,lung,prostate,oral squamous cell carcinoma and colon cancer cell lines.	price>
R-R-3937	Salbutamol-d9 CAS No.1173021-73-2	Salbutamol-d9/CAS No.1173021-73-2 is the deuterium labeled Salbutamol. Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).	price>
R-C-2238	TIC10 isomer CAS：41276-02-2	TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a,possesses superior drug properties:delivery across the blood-brain barrier,superior stability and improved pharmacokinetics.	price>
R-R-3938	Clonidine-d4 hydrochloride CAS No.67151-02-4	Clonidine-d4 (hydrochloride)/CAS No.67151-02-4 is the deuterium labeled Clonidine. Clonidine hydrochloride is an alpha 2-adrenergic agonist.	price>
R-R-3939	Terbutaline-d9 CAS No.1189658-09-0	Terbutaline-d9/CAS No.1189658-09-0 is the deuterium labeled Terbutaline.	price>
R-C-2240	Borussertib CAS：1800070-77-2	Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt,with an IC50 of 0.8nM and a Ki of 2.2nM for Aktwt.	price>
R-R-3940	Carteolol-d9 hydrochloride CAS No.1346602-13-8	Carteolol-d9 (hydrochloride)/CAS No.1346602-13-8 is the deuterium labeled Carteolol hydrochloride. Carteolol hydrochloride (OPC-1085 hydrochloride) is a non-selective beta blocker used to treat glaucoma.	price>
R-C-2241	Lanatoside C CAS：17575-22-3	Lanatoside C is a cardiac glycoside,can be used in the treatment of congestive heart failure and cardiac arrhythmia.Lanatoside C has an IC50 of 0.19μM for dengue virus infection in HuH-7 cells.	price>
R-R-3941	Indacaterol-d3 CAS No.2699828-16-3	Indacaterol-d3/CAS No.2699828-16-3 is deuterium labeled Indacaterol.	price>
R-C-2242	Uprosertib (GSK2141795) CAS：1047634-65-0	Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt,which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.	price>

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