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R-C-2326 Trimethadione CAS:127-48-0 Trimethadione(3,5,5,-Trimethyloxazolidine-2,4-dione)is an oxazolidinedione anticonvulsant agent widely used against absences seizures.Trimethadione also is a T-type calcium channel blocker which has antihyperalgesic effects. price>
R-R-4026 Candesartan-d4 CAS No.1346604-70-3 Candesartan-d4/CAS No.1346604-70-3 is the deuterium labeled Candesartan, which is an angiotensin II receptor antagonist. price>
R-C-2327 SN-6 CAS: 415697-08-4 SN-6 is a selective Na+/Ca2+ exchanger(NCX)inhibitor.SN-6 inhibits NCX1,NCX2, and NCX3 with IC50 of 2.9μM,16μM and 8.6μM, respectively.SN-6 abolishes acetylcholine(ACh)-induced vasodilation. price>
R-R-4027 Olmesartan lactone impurity CAS No.849206-43-5 Olmesartan lactone impurity/CAS No.849206-43-5 is a cyclic ester impurity of Olmesartan. Olmesartan is an angiotensin II receptor (AT1R) antagonist and has the potential for high blood pressure study. price>
R-C-2328 Pinaverium bromide CAS:53251-94-8 Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract,effectively relieves pain,diarrhea and intestinal discomfort,provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome(IBS)patients. price>
R-R-4028 Losartan-d4 (carboxylic acid) CAS No.1246820-62-1 Losartan-d4 (carboxylic acid)/CAS No.1246820-62-1 is the deuterium labeled Losartan (EXP-3174), which is an angiotensin II receptor antagonist. price>
R-C-2329 Strontium Ranelate CAS:135459-87-9 Strontium Ranelate(S12911)is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation,thereby inducing a positive bone balance.Strontium Ranelate also can activate the calcium-sensing receptor (CaSR)in non skeletal cells,resulting in the activation of inositol 1,4,5-triphosphate production and mitogen-activated protein kinase signaling. price>
R-R-4029 Angiotensin II (5-8), human Angiotensin II (5-8), human is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II. Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney. price>
R-C-2330 Bay K 8644 CAS:71145-03-4 Bay K 8644,a dihydropyridine compound,is a specific L-type Ca2+channel agonist.Bay K 8644 increases Ca2+ influx through sarcolemmal Ca2+channels by increasing the open time of the channel. price>
R-R-4030 Losartan-d4 CAS No.1030937-27-9 Losartan-d4/CAS No.1030937-27-9 is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. price>
R-C-2331 Salbutamol CAS:18559-94-9 Salbutamol(Albuterol)is a short-acting,selective beta2-adrenergic receptor agonist used to treat or prevent bronchospasm in patients with asthma, bronchitis,emphysema,and other lung diseases. price>
R-R-4031 trans-Tranilast CAS No.70806-55-2 trans-Tranilast (trans-MK-341)/CAS No.70806-55-2 is an antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis. price>
R-C-2332 Brimonidine CAS:59803-98-4 Brimonidine is a drug used as eye drops under the brand names Alphagan and Alphagan-P to treat open-angle glaucoma or ocular hypertension. price>
R-R-4032 Valsartan-d9 CAS No.1089736-73-1 Valsartan-d9/CAS No.1089736-73-1 is deuterium labeled valsartan. Valsartan is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research. price>
R-C-2333 Synephrine CAS:94-07-5 Synephrine(Oxedrine),an alkaloid,is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium.Synephrine is a sympathomimetic compound and can be used for weight loss. price>
R-R-4033 TD-0212 TFA CAS No.1073549-11-7 TD-0212 TFA/CAS No.1073549-11-7 is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP. price>
R-C-2334 Indacaterol CAS:312753-06-3 Indacaterol(Onbrez;Arcapta)is an ultra-long-acting β-adrenoceptor agonist. price>
R-R-4034 Valsartan Ethyl Ester CAS No.1111177-30-0 Valsartan Ethyl Ester/CAS No.1111177-30-0 is an impurity of Valsartan. Valsartan is an angiotensin II receptor antagonist for the treatment of high blood pressure and heart failure. price>
R-C-2335 Vilanterol Trifenate CAS:503070-58-4 Vilanterol trifenatate(GW642444M)is a novel inhaled long-acting beta2 adrenoceptor agonist with inherent 24-hour activity for once daily treatment of COPD and asthma. price>
R-R-4035 Olmesartan methyl ester CAS No.1347262-29-6 Olmesartan methyl ester/CAS No.1347262-29-6 is an intermediate in the synthesis of Olmesartan medoxomil. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor antagonist with IC50 of 66.2 μM. price>