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R-R-3945 ICB CAS:2109805-70-9 2-(3-oxo-2,3-Dihydro-1H-cyclopenta[b]naphthalen-1-ylidene)malononitrile/ICB/CAS:2109805-70-9 is an active pharmaceutical ingredient.It finds application in the synthesis of specific dyes, pharmaceutical intermediates(which can be used to prepare MOF ligands), and as a component in the formulation of adhesives or coatings. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2246 Oridonin (NSC-250682) CAS:28957-04-2 Oridonin(NSC-250682),a diterpenoid isolated from Rabdosia rubescens,acts as an inhibitor of AKT,with IC50s of 8.4 and 8.9μM for AKT1 and AKT2;Oridonin possesses anti-tumor,anti-bacterial and anti-inflammatory effects. price>
R-R-3946 RDS6 CAS:56347-27-4 3-Hexyl-2-thioxo-1,3-thiazolidin-4-one/RDS6/CAS:56347-27-4 is a chemical compound with a complex but specific structure.It finds application in the synthesis of specific dyes, pharmaceutical intermediates(which can be used to prepare MOF ligands), and as a component in the formulation of adhesives or coatings. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2247 Scutellarin CAS: 27740-01-8 Scutellarin(Breviscapine,Breviscapin,Scutellarein-7-glucuronide),the major active principal flavonoids extracted from the Chinese herbal medicines Scutellaria baicalensis and Erigeron breviscapus(Vant.)Hand-Mazz,has many pharmacological effects,such as antioxidant,antitumor,antiviral,and antiinflammatory activities.Scutellarin can down-regulates the STAT3/Girdin/Akt signaling in HCC cells,and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. price>
R-R-3947 2-(6-Oxo-5,6-dihydro-4H-cyclopenta[b]thiophen-4-ylidene)malononitrile CAS:2098784-70-2 2-(6-Oxo-5,6-dihydro-4H-cyclopenta[b]thiophen-4-ylidene)malononitrile/CAS:2098784-70-2 is a chemical compound with a complex but specific structure.It finds application in the synthesis of specific dyes, pharmaceutical intermediates(which can be used to prepare MOF ligands), and as a component in the formulation of adhesives or coatings. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2248 ABTL-0812 CAS:57818-44-7 ABTL-0812(α-Hydroxylinoleic acid)induces endoplasmic reticulum(ER)stress-mediated autophagy.ABTL-0812 is a first-in-class small molecule with anti-cancer activity. price>
R-R-3948 2-(3-Ethyl-4-oxothiazolidin-2-ylidene)malononitrile CAS:623558-68-9 2-(3-Ethyl-4-oxothiazolidin-2-ylidene)malononitrile/2-(3-Ethyl-4-oxo-2-thiazolidinylidene)propanedinitrile/CAS:623558-68-9 is a monomer that can be used to make polymers. It is a low energy polymer that can be used in solar cells. This monomer has an orbital with the same symmetry as benzene, which allows it to copolymerize with other polymers. 2-(3-Ethyl-4-oxo-2-thiazolidinylidene)propanedinitrile is also photovoltaic and can be used for devices such as solar cells. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2249 AT13148 CAS: 1056901-62-2 AT13148 is an orally active and ATP-competitive,multi-AGC kinase inhibitor with IC50s of 38nM/402 nM/50nM,8nM,3nM,and 6nM/4nM for Akt1/2/3,p70S6K,PKA,and ROCKI/II,respectively. price>
R-R-3949 3-Ethylrhodanine CAS :7648-01-3 3-Ethylrhodanine/3-Ethyl-2-Thioxo-1,3-Thiazolan-4-One/CAS :7648-01-3 is a merocyanine dye that has an ethyl group attached to the rhodanine ring. It is produced by condensation of 2-bromo-3-nitrobenzoic acid with carbon disulfide in the presence of an acceptor molecule. This chemical process can be carried out at room temperature and produces high yields. 3-Ethylrhodanine has been shown to have a variety of electrochemical applications, such as nature, devices, morphology and efficiencies. The red shift observed in this dye was found to be due to the alkyl substituents on the carbon atoms adjacent to the nitrogen atom in the rhodanine ring. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. price>
R-C-2250 Cinobufagin CAS:470-37-1 Cinobufagin(Cinobufagine),an active ingredient of Venenum Bufonis,inhibits tumor development.Cinobufagin increases ATM and Chk2 and decreases CDC25C,CDK1,and cyclin B.Cinobufagin inhibits PI3K,AKT and Bcl-2 while increases levels of cleaved caspase-9 and caspase-3. Thus,Cinobufagin induces cell cycle arrest at the G2/M phase and apoptosis. price>
R-R-3950 Midodrine-d6 hydrochloride CAS No.1188265-43-1 Midodrine-d6 (hydrochloride)/CAS No.1188265-43-1 is deuterium labeled Midodrine, which is a vasopressor/antihypotensive agent. price>
R-R-3951 Vilanterol-d4 trifenatate CAS No.2021249-10-3 Vilanterol-d4 (trifenatate)/CAS No.2021249-10-3 is deuterium labeled Vilanterol (trifenatate). Vilanterol trifenatate (GW642444 trifenatate) is a long-acting β2-adrenoceptor (β2-AR) agonist with inherent 24-hour activity. The pEC50s for β2-AR, β1-AR and β3-AR are 10.37, 6.98 and 7.36, respectively. price>
R-R-3952 Oxprenolol-d7 CAS No.1189805-10-4 Oxprenolol-d7/CAS No.1189805-10-4 is the deuterium labeled Oxprenolol. Oxprenolol (Ba 39089 free base) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle. price>
R-R-3953 Brimonidine-d4 CAS No.1184971-51-4 Brimonidine-d4/CAS No.1184971-51-4 is the deuterium labeled Brimonidine. Brimonidine (UK 14304) is a full α2-adrenergic receptor (α2-AR) agonist. price>
R-R-3954 Benoxathian hydrochloride CAS No.92642-97-2 Benoxathian hydrochloride/CAS No.92642-97-2 is a potent α1 adrenoceptor antagonist, can be used for researching anorexia. price>
R-R-3955 Brimonidine-d4 D-tartrate CAS No.1316758-27-6 Brimonidine-d4 (D-tartrate)/CAS No.1316758-27-6 is the deuterium labeled Brimonidine D-tartrate. price>
R-R-3956 Tetrahydrozoline-d4 hydrochloride CAS No.1246814-66-3 Tetrahydrozoline-d4 (hydrochloride)/CAS No.1246814-66-3 is the deuterium labeled Tetrahydrozoline hydrochloride. Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion. price>
R-R-3957 ST91 CAS No.4749-61-5 ST91/CAS No.4749-61-5 is a α2-adrenoceptor (α2AR) agonist. ST91 activates both α2AAR and non-α2AAR subtypes to produce spinal antinociception. price>
R-R-3958 Octopamine-d4 hydrochloride CAS No.1219803-62-9 Octopamine-d4 (hydrochloride)/CAS No.1219803-62-9 is the deuterium labeled Octopamine hydrochloride. Octopamine ((±)-p-Octopamine) hydrochloride, a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. Octopamine hydrochloride can stimulate alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells transfected with human alpha2-ARs. Octopamine hydrochloride increased glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis and the portal perfusion pressure. price>
R-R-3959 Amitriptyline hydrochloride (Standard) CAS No.549-18-8 Amitriptyline (hydrochloride) (Standard)/CAS No.549-18-8 is the analytical standard of Amitriptyline (hydrochloride). This product is intended for research and analytical applications. Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity. price>