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AP26113-analog (ALK-IN-1)

AP26113-analog (ALK-IN-1)

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-C-2186 100mg 225.00
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R-C-2186 200mg 400.00
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R-C-2186 500mg 700.00
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Product description

AP26113 is an orally-available,potent,and selective inhibitor of ALK with a potency of 0.62nM against wild-type and activity against a wide range of mutants,including the crizotinib-resistant L1196M line.In a panel of EML4-ALK or NPM-ALK-positive cell lines,AP26113 has IC50 values of 4-31 nM.AP26113 is effective against sensitive and resistant H3122 cells,reducing cell growth, suppressing ALK phosphorylation,and inducing apoptosis. 

AP26113-analog (ALK-IN-1)

Appearance N/A
Molecular Weight N/A
purity >95%
PDI by GPC <1.5
Solubility N/A
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 3 weeks
Stability 2 years
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