AP26113-analog (ALK-IN-1)
AP26113-analog (ALK-IN-1)
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-C-2186 | 100mg | 225.00 | + Add to cart |
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R-C-2186 | 200mg | 400.00 | + Add to cart |
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R-C-2186 | 500mg | 700.00 | + Add to cart |
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Product description
AP26113 is an orally-available,potent,and selective inhibitor of ALK with a potency of 0.62nM against wild-type and activity against a wide range of mutants,including the crizotinib-resistant L1196M line.In a panel of EML4-ALK or NPM-ALK-positive cell lines,AP26113 has IC50 values of 4-31 nM.AP26113 is effective against sensitive and resistant H3122 cells,reducing cell growth, suppressing ALK phosphorylation,and inducing apoptosis.
Appearance | N/A |
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Molecular Weight | N/A |
purity | >95% |
PDI by GPC | <1.5 |
Solubility | N/A |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 3 weeks |
Stability | 2 years |
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