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R-R-3770 | Cobalt tetramethoxyphenylporphyrin CAS :28903-71-1 | Cobalt tetramethoxyphenylporphyrin/5,10,15,20-Tetrakis (4-methoxyphenyl)-21H,23H-porphine cobalt (II)/CAS :28903-71-1 is a metal chelate that binds to hydroxyl groups of organic compounds and removes them from wastewater. Cobalt tetramethoxyphenylporphyrin has been shown to be a stable complex, with the proton being bound to the metal atom. The basic structure of this metal chelate is methoxy groups, which are electron-donating groups. The oxidation catalyst for this reaction mechanism is activated by heat and light. This reaction mechanism can proceed in neutral or alkaline conditions. Activation energies for this type of chemical reaction are often high due to the need for the electrons to be transferred from one molecule to another. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. | price> |
R-C-2071 | Branebrutinib (BMS-986195) CAS:1912445-55-6 | Branebrutinib(BMS-986195)is a highly potent,selective covalent,irreversible inhibitor of Bruton is tyrosine kinase(BTK),with an IC50 of 0.1nM. | price> |
R-R-3771 | 5,10,15,20-Tetra(4-pyridyl)porphyrin CAS:16834-13-2 | Tetra(4-pyridyl)porphyrin (TPP)/CAS:16834-13-2 is a model system for studying the interaction of silver ions and inhibitor molecules. TPP is a coordination compound with the chemical formula C20H14N2O3P4. It has been shown to be an efficient inhibitor of tumor xenografts, inhibiting cell cytoplasmic processes such as protein synthesis and DNA replication. The reaction mechanism of this compound has been studied by multi-walled carbon, electrochemical impedance spectroscopy, Langmuir adsorption isotherms, and fluorescence properties. The binding constants for TPP have been determined to be in the range of 109 - 1010 L mol-1. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. | price> |
R-C-2072 | Astemizole CAS: 68844-77-9 | Astemizole is a potent antihistamine(H1-receptor antagonist,IC50=4nM)that displays selectivity over dopamine,5-HT,and muscarinic acetylcholine receptors.This compound has shown potent hERG K+ channel blocking activity (IC50=0.9nM),antimalarial activity in multidrug resistant strains in vitro(IC50=227-734nM),and has been used as a chaperone to correct folding defects and restore protein function for some mutated forms of hERG channels. | price> |
R-R-3772 | Titanyl Phthalocyanine CAS :26201-32-1 | Titanyl Phthalocyanine (PtPc)/CAS :26201-32-1 is a metal-organic compound that belongs to the class of phthalocyanines. It has been purified through sublimation. Pt Pc can be used as a ligand for metals such as titanium, which is an important material in many industrial applications. This compound has been shown to fluoresce under ultraviolet light and can be used to study the properties of monolayers and bilayers. The Langmuir adsorption technique is used to measure the energies of PtPc at the interface between two phases, which are monolayers or bilayers. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. | price> |
R-C-2073 | Oxaliplatin CAS:61825-94-3 | Oxaliplatin is an organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane(DACH)and with an oxalate ligand as a leaving group.A leaving group is an atom or a group of atoms that is displaced as a stable species taking with it the bonding electrons.The DACH side chain appears to inhibit alkylating-agent resistance. | price> |
R-R-3773 | Zinc(II) Tetraphenylporphyrin CAS :14074-80-7 | Zinc(II) Tetraphenylporphyrin/CAS :14074-80-7 is a natural organic compound that can be found in the human body. It has been shown to have anti-angiogenic properties and can be used for the treatment of choroidal neovascularization (CNV). Tetraphenylporphyrin is a redox active molecule that has a high redox potential, which makes it an ideal candidate for use in photoactive systems. Tetraphenylporphyrin has been shown to inhibit the proliferation of tumor cells by interfering with lipid synthesis and transferring electrons from one molecule to another. The chemical structure of tetraphenylporphyrin makes it possible for light exposure to induce a frequency shift, which leads to light emission at 590 nm. This emission is due to the hydroxyl group present on tetraphenylporphyrin, which acts as an electron donor. We can mass produce (kg level), process scaling up, pilot supply, raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. | price> |
R-C-2074 | CCT245737 CAS:1489389-18-5 | CCT245737 is a potent, selective and orally active checkpoint kinase 1(CHK1) inhibitor.CCT245737 showed CHK1 IC50=1.3nM,CHK2 IC50=2440nM,G2 check point abrogation IC50=30nM.Mouse F(oral)=100%.CCT245737 demonstrated a favorable physicochemical,PK,and PD-efficacy profile.The serine-threonine kinase CHK1 is a critical component of the cellular response to DNA damage,especially the repair of DNA breaks arising during replication or caused by DNA damaging chemotherapies and ionizing radiation. | price> |
R-R-3774 | Terazosin hydrochloride CAS No.63074-08-8 | Terazosin hydrochloride/CAS No.63074-08-8 is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin hydrochloride works by relaxing blood vessels and the opening of the bladder. Terazosin hydrochloride has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment. | price> |
R-C-2075 | SJB2-043 CAS:63388-44-3 | SJB2-043 is one of analogs/derivatives of C527,which is a novel and potent USP1 (ubiquitin-specific protease 1)inhibitor. | price> |
R-R-3775 | Levobunolol hydrochloride CAS No.27912-14-7 | Levobunolol (l-Bunolol) hydrochloride/CAS No.27912-14-7 is a potent and nonselective β-adrenergic receptor antagonist. Levobunolol hydrochloride is an ocular hypotensive agent and lowers mean intraocular pressure (IOP). Levobunolol hydrochloride can be used for glaucoma and superior oblique myokymia (SOM) research. | price> |
R-C-2076 | SU14813 CAS: 627908-92-3 | SU14813 is a multi-targeted receptor tyrosine kinases inhibitor with IC50s of 50,2,4,15 nM for VEGFR2,VEGFR1,PDGFRβ and KIT. | price> |
R-R-3776 | Isoferulic acid CAS No.537-73-5 | Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)/CAS No.537-73-5 is a cinnamic acid derivative that has antidiabetic activity. Isoferulic acid binds to and activates α1-adrenergic receptors (IC50=1.4 µM) to enhance secretion of β-endorphin (EC50=52.2 nM) and increase glucose use. Isoferulic acid also has anti-influenza virus activities. | price> |
R-R-3777 | Medetomidine CAS No.86347-14-0 | Medetomidine/CAS No.86347-14-0 is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine has sedative and analgesic effects. Medetomidine can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels. | price> |
R-C-2078 | Fmoc-Ser(Ac3GalNAcα)-OH CAS:120173-57-1 | Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH is a drug for cancer. | price> |
R-R-3778 | Bevantolol hydrochloride CAS No.42864-78-8 | Bevantolol hydrochloride/CAS No.42864-78-8 is a selective β1 and α1-adrenergic receptor antagonist with pKi values of 7.83, 6.9 in rat cerebral cortex, respectively. Bevantolol hydrochloride is a potent Ca2+ antagonist. | price> |
R-C-2079 | E-7046 CAS:1369489-71-3 | E7046 is an orally bioavailable and specific EP4 antagonist,with IC50 of 13.5nM and Ki of 23.14nM,exhibiting anti-tumor activities. | price> |
R-R-3779 | Bambuterol hydrochloride CAS No.81732-46-9 | Bambuterol hydrochloride/CAS No.81732-46-9 ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a proagent of terbutaline. | price> |
R-C-2080 | Bemcentinib (R428) CAS:1037624-75-1 | Bemcentinib(R428,BGB324)is an inhibitor of Axl with IC50 of 14 nM,>100-fold selective for Axl versus Abl.Selectivty for Axl is also greater than Mer and Tyro3(50-to-100- fold more selective)and InsR,EGFR,HER2,and PDGFRβ(100- fold more selective). | price> |
R-R-3780 | Dabuzalgron CAS No.219311-44-1 | Dabuzalgron (Ro 115-1240)/CAS No.219311-44-1 is an orally active and selective α-1A adrenergic receptor agonist for the treatment of urinary incontinence. Dabuzalgron protects against Doxorubicin-induced cardiotoxicity by preserving mitochondrial function. | price> |