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Catalog	name	Description	price
R-R-3816	Tasipimidine sulfate CAS No.1465908-73-9	Tasipimidine sulfate/CAS No.1465908-73-9 is an orally active and selective α2A-adrenoceptor agonist with a pEC50 of 7.57 against human α2A-adrenoceptor. Tasipimidine sulfate can be used for situational anxiety and fear research.	price>
R-C-2117	EOAI3402143 CAS：1699750-95-2	EOAI3402143 is a novel dose-dependent inhibitor of Usp9x and Usp24 activity, increasing tumor cell apoptosis and fully blocking or regressing myeloma tumors in mice.	price>
R-R-3817	Propranolol-d7 (ring-d7) CAS No.344298-99-3	Propranolol-d7 (ring-d7)/CAS No.344298-99-3 is the deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM. Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.	price>
R-C-2118	GS-4361 CAS：2291164-02-6	GS-4361 is a potent and selective IDO1 inhibitor with an EC50 of 17nM,GS-4361 was first reported in patent WO2019040102A.	price>
R-R-3818	4-Hydroxyatomoxetine CAS No.435293-66-6	4-Hydroxyatomoxetine/CAS No.435293-66-6 is an active metabolite of Atomoxetine. 4-Hydroxyatomoxetine is metabolized by the enzyme cytochrome P450 2D6 (CYP2D6). Atomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5 nM, 77 nM and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively).	price>
R-C-2119	NTN21277（Gefitinib-based PROTAC 3） CAS：2230821-27-7	NTN21277（Gefitinib-based PROTAC 3 )is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7nM and 22.3nM for HCC827 cell(Exon 19 del)and H3255 cell(L858R).	price>
R-R-3819	Zinterol hydrochloride CAS No.38241-28-0	Zinterol hydrochloride (MJ 9184 hydrochloride)/CAS No.38241-28-0 is a potent and selective β2-adrenoceptor agonist. Zinterol hydrochloride increases ICa in a concentration-dependent manner with an EC50 of 2.2 nM. Zinterol hydrochloride induces ventricular arrhythmias in conscious heart failure rabbits.	price>
R-C-2120	CL2A-SN-38 CAS：1279680-68-0	CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate(ADC).CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types.	price>
R-R-3820	A-61603 CAS No.107756-30-9	A-61603/CAS No.107756-30-9 is a selective α1A-adrenergic receptor agonist. A-61603 increases the frequency of spontaneous Ca2+ transients in rat ventricular myocytes in vitro.	price>
R-C-2121	PK11007 CAS： 874146-69-7	PK11007 is a mild thiol alkylator with anticancer activity.PK11007 stabilizes p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity.PK11007 induces mutant p53 cancer cell death by increasing reactive oxygen species (ROS)levels.	price>
R-R-3821	Landiolol hydrochloride CAS No.144481-98-1	Landiolol hydrochloride (ONO1101 hydrochloride)/CAS No.144481-98-1 is a highly beta1 selective ultra-short acting beta-blocker (β1/β2 selectivity = 255:1, a half-life of 4 min)， acts as an adrenoceptor antagonist.	price>
R-C-2122	KY-226 CAS：1621673-53-7	KY-226 is a potent,selective,orally active and allosteric protein tyrosine phosphatase 1B(PTP1B)inhibitor with an IC50 of 0.25 μM,and without PPARγ agonist activity.KY-226 exerts anti-diabetic and anti-obesity effects by enhancing insulin and leptin signaling,respectively.KY-226 also protects neurons from cerebral ischemic injury.	price>
R-R-3822	Meranzin CAS No.23971-42-8	Meranzin/CAS No.23971-42-8 is an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS). Meranzin, isolated from leaves of Murraya exotica L., regulates the shared alpha 2-adrenoceptor and involves the AMPA-ERK1/2–BDNF signaling pathway. Meranzin has the potential for the prevention of the comorbidity of atherosclerosis and depression.	price>
R-C-2123	LIT-001 CAS： 2245072-21-1	LIT-001 is the first nonpeptide oxytocin receptor(OT-R)agonist(EC50=55 nM;Ki=226nM).LIT-001 improves social interaction in a mouse model of autism.	price>
R-R-3823	PVA/montmorillonite composite aerogel	Polyvinyl alcohol/montmorillonite composite aerogel;PVA/montmorillonite composite aerogel from ruixi.Polyvinyl alcohol/montmorillonite composite aerogel is a lightweight, porous material that is created through a gelation process and subsequent removal of the liquid component, leaving behind a solid interconnected network of pores. This composite aerogel is a combination of polyvinyl alcohol (PVA) and montmorillonite clay, resulting in a material with unique properties that make it suitable for various applications.Applications of polyvinyl alcohol/montmorillonite composite aerogel include thermal insulation in buildings, lightweight structural components, oil spill cleanup materials, and as a component in advanced composites for aerospace and automotive industries, among others.	price>
R-C-2124	JNK-IN-8 CAS：1410880-22-6	JNK-IN-8(JNK Inhibitor XVI)is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 4.7nM,18.7nM and 1nM,>10-fold selectivity against MNK2,Fms and no inhibition to c-Kit,Met,PDGFRβin A375 cell line.	price>
R-R-3824	PVA/silica composite aerogel	Polyvinyl alcohol/silica composite aerogel;PVA/silica composite aerogel;Polyvinyl alcohol/sio2 composite aerogel;PVA/sio2 composite aerogel from ruixi. Polyvinyl alcohol/silica composite aerogel is a remarkable material that combines the properties of polyvinyl alcohol (PVA) with those of silica to create a lightweight, highly porous substance with a wide range of applications. Applications of polyvinyl alcohol/silica composite aerogel include thermal insulation in buildings, lightweight structural components in aerospace and automotive industries, environmental cleanup materials, and as a medium for controlled drug release and biomedical scaffolding.	price>
R-C-2125	INCB8761(PF-4136309) CAS：1341224-83-6	PF-4136309(INCB8761)is a potent,selective,and orally bioavailable antagonist of C-C chemokine receptor type 2(CCR2 or CD192(cluster of differentiation 192)with IC50 of 5.2nM,17nM and 13nM for human,mouse and rat CCR2,respectively.	price>
R-R-3825	PVA/ZnO composite aerogel	PVA/ZnO composite aerogel;Polyvinyl alcohol/zinc oxide composite aerogel;PVA/zinc oxide composite aerogel;Polyvinyl alcohol/ZnO composite aerogel from ruixi.Polyvinyl alcohol/zinc oxide (PVA/ZnO) composite aerogel is a remarkable material that combines the unique properties of polyvinyl alcohol (PVA) with those of zinc oxide to create a lightweight, porous substance with a wide range of potential applications. This composite aerogel is typically produced through a sol-gel process, followed by supercritical drying to remove the liquid component, resulting in a solid, interconnected porous structure.The combination of polyvinyl alcohol and zinc oxide in an aerogel composite offers a material with diverse properties, making it valuable in various industries and applications where lightweight, UV protection, antibacterial properties, and mechanical strength are desirable.	price>
R-C-2126	LY900009 CAS：209984-68-9	LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.LY900009 inhibited plasma levels of amyloid-β peptide in a dose-dependent manner with 80-90% inhibition observed in the 30-to 60-mg cohorts.	price>

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