PF05175157 CAS:1301214-47-0
PF05175157
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-C-1925 | 50mg | 315.00 | + Add to cart |
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R-C-1925 | 100mg | 580.00 | + Add to cart |
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R-C-1925 | 200mg | 890.00 | + Add to cart |
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Product description
PF-05175157 is a potent and selective cetyl-CoA carboxylase(ACC)1 and 2 inhibitor with IC50 values of 27nM and 33 nM,respectively.PF-05175157 led to robust reduction of de novo lipogenesis(DNL),albeit with concomitant reductions in platelet count,which were attributed to the inhibition of fatty acid synthesis within bone marrow.PF-05175157 induced a reduction of the viral load in serum and kidney in WNV-infected mice,unveiling its therapeutic potential for the treatment of chronic kidney disease associated with persistent WNV infection.
Appearance | N/A |
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Molecular Weight | N/A |
purity | >95% |
PDI by GPC | <1.5 |
Solubility | N/A |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 3 weeks |
Stability | 1 year |
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