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Catalog	name	Description	price
R-C-1596	Daprodustat(GSK1278863) CAS:960539-70-2	Daprodustat(GSK1278863)is an orally active hypoxia-inducible factor prolyl hydroxylase(HIF-PH)inhibitor being developed for the treatment of anemia associated with chronic kidney disease.	price>
R-R-3296	BIMU 8 CAS No.134296-40-5	BIMU 8/CAS No.134296-40-5 is a potent and selective 5-HT4 agonist with EC50s of 18 nM, 77 nM, and 540 nM for wild type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4 receptors.	price>
R-C-1597	CH5183284(Debio-1347) CAS:1265229-25-1	CH5183284(Debio-1347,FF284)is a selective and orally available FGFR inhibitor with IC50 of 9.3nM,7.6nM,22 nM,and 290nM for FGFR1,FGFR2,FGFR3,and FGFR4, respectively.	price>
R-R-3297	PF-04995274 CAS No.1331782-27-4	PF-04995274/CAS No.1331782-27-4 is a potent, high-affinity, orally active and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 has an EC50 range of 0.26-0.47 nM for human 5-HT4A/4B/4D/4E (Ki range of 0.15-0.46 nM), and has an EC50 range of 0.59-0.65 nM for rat 5-HT4S/4L/4E (Ki of 0.30 nM for rat 5-HT4S).	price>
R-C-1598	BMS582949(HCl) CAS:912806-16-7 (HCl)	BMS-582949(PS540446)is a potent and selective p38 mitogen-activated protein kinase(p38 MAPK)inhibitor with IC50 of 13nM,inhibiting both p38 kinase activity and activation of p38.	price>
R-R-3298	LP 12 hydrochloride hydrate	LP 12 hydrochloride hydrate is a potent and selective 5-HT7 receptor agonist with a Ki of 0.13 nM. LP 12 hydrochloride hydrate displays selectivity for 5-HT7 over D2, 5-HT1A and 5-HT2A receptors (Ki values are 224 nM, 60.9 nM and >1000 nM, respectively).	price>
R-C-1599	ADX 47273 CAS:851881-60-2	ADX-47273 is a potent,selective and brain-penetrant mGluR5 positive allosteric modulator(PAM),with an EC50 of 0.17 μM for potentiation of glutamate(50nM) response.ADX-47273 has antipsychotic and procognitive activities.	price>
R-R-3299	Temanogrel CAS No.887936-68-7	Temanogrel/CAS No.887936-68-7 is a highly selective 5-HT2A receptor antagonist with a Ki of 4.9 nM.	price>
R-C-1600	ozanimod CAS:1306760-87-1	Ozanimod(RPC-1063)is a potent and selective S1P1 and S1P5 receptor agonist with EC50s of 410 pM and 11 nM in [35S]-GTPγS binding,respectively.	price>
R-R-3300	Cariprazine-d8 CAS No.1308278-50-3	Cariprazine-d8/CAS No.1308278-50-3 is a deuterium labeled Cariprazine. Cariprazine is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).	price>
R-C-1601	K-Ras-IN-1 CAS:84783-01-7	K-Ras-IN-1 is a K-Ras inhibitor.K-Ras-IN-1 binds to K-Ras(WT),K-Ras(G12D),K-Ras(G12V),and H-Ras.K-Ras-IN-1 has potential for the research of pancreatic, colon and lung carcinomas.	price>
R-R-3301	GR127935 hydrochloride CAS No.148642-42-6	GR127935 hydrochloride/CAS No.148642-42-6 is a potent and orally active 5-HT1D and 5-HT1B receptor antagonist with pKis of 8.5 for both isoforms. GR127935 hydrochloride has 100-fold selectivity for 5-HT1B/1D receptors over 5-HT1A, 5-HT2A, and 5-HT2C receptors. GR127935 hydrochloride can be used in neurological disease research.	price>
R-C-1602	Tolvaptan CAS:150683-30-0	Tolvaptan(OPC-41061)is an orally effective nonpeptide arginine vasopressin V2 receptor antagonist with IC50 of 3 nM,used to treat hyponatremia.	price>
R-R-3302	Trazodone CAS No.19794-93-5	Trazodone (AF-1161 free base)/CAS No.19794-93-5 is a serotonin receptor antagonist and reuptake inhibitor. Trazodone can be used for the research of major depressive disorder. Trazodone also has potential for sleep disorder research.	price>
R-C-1603	Mozavaptan CAS:137975-06-5	Mozavaptan(OPC-31260)is a novel competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM,respectively.	price>
R-R-3303	4,4-Diphenylbutylamine hydrochloride CAS No.22101-90-2	4,4-Diphenylbutylamine/CAS No.22101-90-2 shows affinity for the 5-HT2A and H1 receptors with Kis of 2589 and 1670 nM, respectively.	price>
R-C-1604	Conivaptan hydrochloride CAS:168626-94-6	Conivaptan(hydrochloride)is a non-peptide antagonist of vasopressin receptor, with Ki values of 0.48 and 3.04 nM for rat liver V1A receptor and rat kidney V2 receptor respectively.	price>
R-R-3304	Cyamemazine CAS No.3546-03-0	Cyamemazine/CAS No.3546-03-0 is a neuroleptic agent that contains the phenothiazine chromophore. Cyamemazine is often used as an anxiolytic. Cyamemazine is a potent 5-HT3 (Ki of 12 nM), 5-HT2A (Ki = 1.5 nM) and 5-HT2C (Ki of 75 nM) receptors antagonist with antipsychotic activity.	price>
R-C-1605	Lixivaptan CAS：168079-32-1	Lixivaptan(VPA-985,WAY-VPA985)is an orally active and selective vasopressin receptor V2 antagonist,with IC50 values of 1.2 and 2.3 nM for human and rat V2,respectively.	price>
R-R-3305	Quetiapine hemifumarate (Standard) CAS No.111974-72-2	Quetiapine (hemifumarate) (Standard)/CAS No.111974-72-2 is the analytical standard of Quetiapine (hemifumarate). This product is intended for research and analytical applications. Quetiapine hemifumarate is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine hemifumarate has moderate to high affinity for the human D2, HT1A, 5-HT2A, 5-HT2C receptor with pKis of 7.25, 5.74, 7.54, 5.55. Antidepressant and anxiolytic effects.	price>

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