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| Catalog | name | Description | price |
|---|---|---|---|
| R-M-693 | Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt | Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt,CAS: 117399-94-7 from ruixi.Endothelin-1, a 21-amino acid peptide from vascular endothelial cells of different mammalian species, is one of the most potent vasoconstrictors. ET-1 exerts a wide variety of effects on both vascular and non-vascular (e.g. heart, lung, brain) tissues. Toxic peptides from a snake venom, the sarafotoxins, show structural and functional homology to ET-1. The role of ET-1 in clinical hypertension has been reviewed by Dhaun et al. and by Sreenivas and Oparil. ET-1 plays a central role in lung fibrosis. | price> |
| R-R-1846 | Puromycin aminonucleoside CAS No.58-60-6 | Puromycin aminonucleoside (NSC 3056)/CAS No.58-60-6 is the aminonucleoside portion of the antibiotic puromycin, and used in nephrosis animal models. Puromycin aminonucleoside induces apoptosis. Puromycin aminonucleoside is a reversible inhibitor of dipeptidyl peptidase II and cytosol alanyl aminopeptidase. Puromycin aminonucleoside induces secretion of cell migrasome. | price> |
| R-CG-024 | DSPE-Se-Se-PEG-CHO | 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-CHO ,DSPE-Se-Se-PEG-N3 from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-CHO).The product(DSPE-Se-Se-PEG-CHO)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS). | price> |
| R-M-476 | Abz-Gly-p-nitro-Phe-Pro-OH trifluoroacetate salt | Fluorogenic (FRET) substrate for angiotensin I-converting enzyme (ACE). Enzymatic cleavage of Abz-Gly-Nph-Pro yields Abz-Gly-OH emitting at 420 nm. | price> |
| R-M-694 | Endothelin-1 (11-21) trifluoroacetate salt | Endothelin-1 (11-21) trifluoroacetate salt,IRL-1038 (CAS :144602-02-8) from ruixi.IRL-1038 inhibits ET-B receptor-mediated contraction of guinea-pig ileal and tracheal smooth muscle without any significant agonist activity,but does not affect the ET-A receptor-mediated contraction of rat aortic smooth muscle. | price> |
| R-R-1847 | Hsp90-Cdc37-IN-3 CAS No.2361009-68-7 | Hsp90-Cdc37-IN-3 (Compound 9)/CAS No.2361009-68-7 is a novel celastrol−imidazole derivative with anticancer activity. Hsp90-Cdc37-IN-3 inhibits Hsp90−Cdc37 by covalent-binding, and induces apoptosis. | price> |
| R-CG-025 | DSPE-Se-Se-PEG-OH | 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-hydroxyl,DSPE-Se-Se-PEG-OH from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-OH).The product(DSPE-Se-Se-PEG-OH)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS). | price> |
| R-M-477 | 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt | Abz-Gly-Pro-D-Leu-D-Ala-NHOH (FN439) is a inhibitor of matrix metalloproteinases. It inhibits interstitial and granulocyte collagenases (IC50 = 1 uM), granulocyte gelatinase (IC50 = 30 uM) and skin fibroblast stromelysin (IC50 = 150 uM) but not thermolysin and serine proteinases. It retains activity after incubation with pronase or human granulocyte elastase. | price> |
| R-M-695 | Endothelin-2 (human, canine) acetate salt | Endothelin-2 (human,canine) acetate salt,CAS:123562-20-9 from ruixi.It can be applied to cardiovascular system & diseases. | price> |
| R-R-1848 | Fenoldopam mesylate CAS No.67227-57-0 | Fenoldopam mesylate (SKF-82526)/CAS No.67227-57-0 is a D1 receptor agonist and a novel lysine-specific demethylase 1 (LSD1) inhibitor (IC50=0.8974 μM). Fenoldopam mesylate shows anti-hypertensive effects, anti-cancer cell proliferation activity and can induce cells apoptosis. | price> |
| R-CG-026 | DSPE-Se-Se-PEG-fitc | 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-(polyethylene glycol)-fluorescence,DSPE-Se-Se-PEG-fitc from ruixi.The diselenium bond(se-se) is a new type of GSH responsive covalent chemical bond. DSPE is linked to the double selenium bond then coupling PEG thiol(peg-fitc).The product(DSPE-Se-Se-PEG-fitc)with GSH responsive double selenium micelles was prepared.By using the double selenium bond material, the drug can be released from the carrier rapidly in the environment of high GSH, so it can be used in drug delivery system (DDS). | price> |
| R-M-478 | Abz-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂ trifluoroacetate salt | Abz-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂ trifluoroacetate salt,a broad-spectrum MMP substrate | price> |
| R-R-1849 | PTC-028 CAS No.1782970-28-8 | PTC-028/CAS No.1782970-28-8 is an inhibitor of stem cell factor BMI-1 in ovarian cancer that is orally bioavailable. PTC-028 selectively inhibits cancer cells while normal cells remain unaffected. PTC-028 downregulates BMI-1, inducing caspase-mediated apoptosis. | price> |
| R-CG-027 | PLGA-s-s-PEG-COOH | Poly(L-lactide-co-glycolide)-s-s-Polyethylene glycol-carboxylic acid,PLGA-s-s-PEG-COOH from ruixi.Disulfide bond has GSH response effect. PLGA is connected with disulfide bond, then peg COOH (PEG COOH) is coupled to form plga-s-s-peg-cooh. The product can be used to prepare micelles or vesicles and other new targeted products for drug encapsulation. | price> |
| R-M-479 | Abz-Ser-Pro-3-nitro-Tyr-OH | Abz-Ser-Pro-3-nitro-Tyr-OH (CAS# 553644-01-2) is a useful research chemical compound.Selective substrate for angiotensin-converting enzyme 2 (ACE2), an ACE homolog which differs in its specificity and physiological role from ACE.The internally quenched fluorescent (FRET) substrate is potentially useful in applications such as high-throughput screening of ACE2 inhibitors. | price> |
| R-M-697 | Endothelin-3 (human, mouse, rabbit, rat) acetate salt | Endothelin-3 (human, mouse, rabbit, rat) acetate salt ,CAS :117399-93-6 from ruixi.ET-1, ET-2, and ET-3 are the products of three distinct endothelin genes. ET-2 and ET-3 are similar to ET-1, but differ in two and six amino acids, respectively. All three isopeptides produce strong in vitro vasoconstrictor and in vivo pressor responses. However, the quantitative profiles of their pharmacological activities vary greatly. | price> |
| R-M-706 | Atrial Natriuretic Factor (1-28) (human) acetate salt | Atrial Natriuretic Factor (1-28) (human) acetate salt(CAS: 89213-87-6)from ruixi.The product is only used for scientific research, not for human body. | price> |
| R-R-1850 | Morroniside CAS No.25406-64-8 | Morroniside/CAS No.25406-64-8 has neuroprotective effect by inhibiting neuron apoptosis and MMP2/9 expression. | price> |
| R-M-698 | Met-Lys-Bradykinin | Met-Lys-Bradykinin,CAS :550-19-6 from ruixi. It is a synthetic peptide. | price> |
| R-CG-028 | PLGA-S-S-PEG-biotin | Poly(L-lactide-co-glycolide)-s-s-Polyethylene glycol-biotin,PLGA-S-S-PEG-biotin from ruixi.PLGA is connected with disulfide bond, then peg biotin (PEG biotin) is coupled to form plga-s-s-peg-biotin.The product can be used to prepare micelles or vesicles and other new targeted products for drug encapsulation. | price> |

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