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Catalog	name	Description	price
R-R-1401	Bromosporine CAS No.1619994-69-2	Bromosporine/CAS No.1619994-69-2 is a potent BET inhibitor with an IC50 value of 2.1 μM for PCAF. Bromosporine can arrest cell cycle and induce apoptosis in cancer cells. Bromosporine exhibits excellent antitumor activity in xenograft mice model when combined with 5-FU (HY-90006). Bromosporine can increase CDK9 T-loop phosphorylation in HIV-1 latency models, resulting the protection of reactivate HIV-1 replication from latency. Bromosporine can be used to research colorectal cancer, acute myeloid leukemia (AML) and AIDS.	price>
R-mo-268	COF-14,Covalent organic framework-14	COF-14,Covalent organic framework-14 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.	price>
R-R-1402	Borrelidin CAS No.7184-60-3	Borrelidin (Treponemycin)/CAS No.7184-60-3 is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor which is a nitrile-containing macrolide antibiotic isolated from Streptomyces rochei. Borrelidin is an inhibitor of Cdc28/Cln2 of the budding yeast, with an IC50 of 24 μM. Borrelidin is a potent angiogenesis inhibitor, with an IC50 of 0.8 nM. Borrelidin induces apoptosis in the tube-forming cells. Borrelidin has strong antimalarial activities, with IC50s of 1.9 nM and 1.8 nM against K1 and FCR3 strains of Plasmodium falciparum, respectively.	price>
R-OR-303	Cholesterol-Ova	Cholesterol-Ovalbumin Cholesterol-Ova from ruixi Cholesterol is an indispensable and important substance in animal tissue and cell. It not only participates in the formation of cell membrane, but also is the raw material for the synthesis of bile acid, vitamin D and steroids.Ovalbumin is a high quality protein.	price>
R-mo-269	COF-16,Covalent organic framework-16	COF-16,Covalent organic framework-16 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.Cof-16 is an alkylated porous polymer material.	price>
R-R-1403	Penfluridol CAS No.26864-56-2	Penfluridol (R-16341)/CAS No.26864-56-2 is a potent, long-acting, first-generation, oral diphenylbutylpiperidine antipsychotic agent by targeting D2-like dopamine receptor. Penfluridol effectively inhibits TNFα-induced NF-κB activation and alleviates the severity of arthritis and colitis in vivo. Penfluridol is a Ca2+-calmodulin inhibitor. Penfluridol induces apoptosis and autophagy. Penfluridol is used for chronic schizophrenia, acute psychosis, Tourette syndrome and autoimmune diseases. Penfluridol inhibites the growth of E. faecalis planktonic cells with the MIC of 7.81 µg/ml.	price>
R-mo-270	COF-105,Covalent organic framework-105	COF-105,Covalent organic framework-105 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.As a balance between low skeleton density and large porosity, cof-105 shows high energy storage capacity.	price>
R-R-1404	Idebenone CAS No.58186-27-9	Idebenone/CAS No.58186-27-9, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM). Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells. Idebenone quickly crosses the blood-brain barrier.	price>
R-OR-304	Chitosan- mannose	Chitosan- mannose Chitosan- mannose from ruixi Mannose modified chitosan.Chitosan is the product of natural polysaccharide chitin to remove part of acetyl group. It has many physiological functions such as biodegradation, biocompatibility, nontoxicity, bacteriostasis, anticancer, lipid-lowering, immune enhancement and so on. It is widely used in many fields such as medical fiber, biomedical field, tissue engineering carrier material, medical treatment and drug development and other daily chemical industry.	price>
R-mo-271	COF-320,Covalent organic framework-320	COF-320, Covalent organic framework-320 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.	price>
R-R-1405	Capmatinib dihydrochloride hydrate CAS No.1865733-40-9	Capmatinib (INC280; INCB28060) dihydrochloride hydrate/CAS No.1865733-40-9 is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor (IC50=0.13 nM). Capmatinib dihydrochloride hydrate can inhibit phosphorylation of c-MET as well as c-MET pathway downstream effectors such as ERK1/2, AKT, FAK, GAB1, and STAT3/5. Capmatinib dihydrochloride hydrate potently inhibits c-MET-dependent tumor cell proliferation and migration and effectively induces apoptosis. Antitumor activity. Capmatinib dihydrochloride hydrate is largely metabolized by CYP3A4 and aldehyde oxidase.	price>
R-OR-305	Cyclodextrin modified gold nanoparticles 50NM	Cyclodextrin modified gold nanoparticles 50NM Cyclodextrin modified gold nanoparticles 50NM from ruixi Among the numerous nanoparticles, gold nanoparticles (aupns) have been widely used in sensing, assembly, catalysis, drug delivery and so on because of their unique properties and potential applications. In this gentle way, cyclodextrin is cleverly combined with gold nanoparticles.	price>
R-mo-273	COF-22, Covalent organic framework-22	COF-22, Covalent organic framework-22 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.	price>
R-R-1406	(E/Z)-Eltrombopag-13C4 CAS No.1217230-31-3	(E/Z)-Eltrombopag-13C4/CAS No.1217230-31-3 is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag can be used for the research of cardiovascular. Eltrombopag also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag can induce apoptosis in hepatocellular carcinomab (HCC) as well.	price>
R-OR-306	Water soluble silver nanoparticles 80nm,LSPR488nm	Water soluble silver nanoparticles(80nm,LSPR488nm) Water soluble silver nanoparticles 80nm,LSPR488nm from ruixi The material is insoluble in water but can be dispersed in water.As one of the important precious metal nanomaterials, silver nanoparticles have been widely studied and applied in many fields, such as catalysis, biological and chemical sensing, nonlinear optics, surface enhanced Raman scattering, cytotoxicity, antibacterial test, dark field imaging, electronics and so on, because of their excellent SPR characteristics in visible light region.	price>
R-mo-274	COF-20,Covalent organic framework-20	COF-20,Covalent organic framework-20 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.	price>
R-R-1407	KRAS inhibitor-9 CAS No.300809-71-6	KRAS inhibitor-9/CAS No.300809-71-6, a potent KRAS inhibitor (Kd=92 μM), blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 binds to KRAS G12D, KRAS G12C and KRAS Q61H protein with a moderate binding affinity. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSCLC cells with KRAS mutation but not normal lung cells.	price>
R-OR-307	MPEG2K-SS-PEI25K	methoxy polyethylene glycol2K-S-S-Polyethylenimine25K MPEG2K-SS-PEI25K from ruixi One end of the disulfide bond is connected with polyethylene glycol monomethyl ether, and the other end is connected with polyethylene amine	price>
R-mo-275	COF-63,Covalent organic framework-63	COF-63,Covalent organic framework-63 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.	price>
R-R-1408	Asiatic acid CAS No.464-92-6	Asiatic acid/CAS No.464-92-6, a pentacyclic triterpene found in Centella asiatica (Centella asiatica), has anticancer activity. Asiatic acid induces apoptosis in melanoma cells and has barrier protective effects on human aortic endothelial cells (HAEC). Asiatic acid also has anti-inflammatory activity and inhibits tumor necrosis factor (TNF)-α-induced endothelial barrier dysfunction. Asiatic acid also inhibits NLRP3 inflammasome activation and NF-κB pathway, effectively inhibits inflammation in rats, and has neuroprotective effects in rat spinal cord injury (SCI) model.	price>

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