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MRT199665 CAS No.1456858-57-3
MRT199665 CAS No.1456858-57-3
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-1390 | 5mg | 560.00 | + Add to cart |
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| R-R-1390 | 10mg | 930.00 | + Add to cart |
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Product description
MRT199665/CAS No.1456858-57-3 is a potent and ATP-competitive, selective MARK/SIK/AMPK inhibitor with IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively. MRT199665 causes apoptosis in MEF2C-activated human acute myeloid leukemias (AML) cells. MRT199665 inhibits the phosphorylation of SIK substrate CRTC3 at S370.
| Appearance | N/A |
|---|---|
| Molecular Weight | 469.58 |
| Purity | >90% |
| CAS | 1456858-57-3 |
| Formula | C28H31N5O2 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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