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R-R-1417 Omigapil maleate CAS No.200189-97-5 Omigapil maleate/CAS No.200189-97-5, an orally bioavailable GAPDH nitrosylation inhibitor, abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice.Omigapil maleate (CGP3446B maleate) is a apoptosis inhibitor. Omigapil maleate can be used for the research of congenital muscular dystrophy (CMD). Omigapil (maleate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. price>
R-OR-317 DSPE-Se-Se-PEG-NH2 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-Polyethylene glycol-Amine dspe-se-se-peg-nh2 from ruixi 1,2-distearoylphosphatidylethanolamine(DSPE) is a phosphatidylethanolamine in which the phosphatidyl acyl group at C-1 and C-2 is stearoyl. It derives from an octadecanoic acid. It is a conjugate base of a 1,2-distearoylphosphatidylethanolaminium. It is a tautomer of a 1,2-distearoylphosphatidylethanolamine zwitterion.One end of the acylhydrazone bond is connected with DSPE, and the other end is connected with Amine. price>
R-mo-284 CCOF-2,Chiral covalent organic frameworks-2 CCOF-2,Chiral covalent organic frameworks-2 from ruixi.CCOF was synthesized from chiral taddol precursor with helical structure and diamine precursor with flexible structure. It is a covalent organic framework material with double interpenetrating network. COFS can be crystallized in mild conditions. Two dimensional chiral COF materials are ccof-1 and ccof-2. price>
R-R-1418 cRIPGBM chloride CAS No.2361988-77-2 cRIPGBM chloride/CAS No.2361988-77-2, an orally active, proapoptotic derivative. cRIPGBM can be generated from glioblastoma multiforme (GBM) cancer stem cells (CSCs). cRIPGBM(chloride) targets to receptor-interacting protein kinase 2 (RIPK2) to induce caspase 1-dependent apoptosis. cRIPGBM(chloride) suppresses the formation of RIPK2/TAK1 (prosurvival complex), and increases the formation of RIPK2/caspase 1 (proapoptotic complex). cRIPGBM(chloride) exerts potent anti-tumor activity in vivo in animal models. price>
R-OR-318 DSPE-Se-Se-PEG-MAL 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-Polyethylene glycol-Maleimide DSPE-Se-Se-PEG-MAL from ruixi 1,2-distearoylphosphatidylethanolamine(DSPE) is a phosphatidylethanolamine in which the phosphatidyl acyl group at C-1 and C-2 is stearoyl. It derives from an octadecanoic acid. It is a conjugate base of a 1,2-distearoylphosphatidylethanolaminium. It is a tautomer of a 1,2-distearoylphosphatidylethanolamine zwitterion.One end of the acylhydrazone bond is connected with DSPE, and the other end is connected with Maleimide. price>
R-mo-285 CCOF-3,Chiral covalent organic frameworks-3 CCOF-3, Chiral covalent organic frameworks-3 from ruixi.CCOF was synthesized from chiral taddol precursor with helical structure and diamine precursor with flexible structure. It is a covalent organic framework material with double interpenetrating network. price>
R-R-1419 (-)-Epigallocatechin Gallate (Standard) CAS No.989-51-5 (-)-Epigallocatechin Gallate (Standard)/CAS No.989-51-5 is the analytical standard of (-)-Epigallocatechin Gallate. This product is intended for research and analytical applications. (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma. price>
R-OR-319 DSPE-Se-Se-PEG-FA 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Se-Se-Polyethylene glycol-Folic acid DSPE-Se-Se-PEG-FA from ruixi 1,2-distearoylphosphatidylethanolamine(DSPE) is a phosphatidylethanolamine in which the phosphatidyl acyl group at C-1 and C-2 is stearoyl. It derives from an octadecanoic acid. It is a conjugate base of a 1,2-distearoylphosphatidylethanolaminium. It is a tautomer of a 1,2-distearoylphosphatidylethanolamine zwitterion.One end of the acylhydrazone bond is connected with DSPE, and the other end is connected with Folic acid(fa). price>
R-mo-286 CCOF-4,Chiral covalent organic frameworks-4 CCOF-4,Chiral covalent organic frameworks-4 from ruixi.CCOF was synthesized from chiral taddol precursor with helical structure and diamine precursor with flexible structure. It is a covalent organic framework material with double interpenetrating network. price>
R-R-1420 Acetylshikonin CAS No.24502-78-1 Acetylshikonin/CAS No.24502-78-1 is an oral active anti-cancer, anti-inflammatory, antioxidant, anti-fertility, antibacterial, and neuroprotective agent. Acetylshikonin is a inhibitor of acetylcholinase (AChE) (IC50=34.6 μM) and nonselective cytochrome P450. Acetylshikonin can induce Apoptosis and Autophagy in cancer cells. Acetylshikonin regulates blood glucose, liver fat metabolism, and renal fibrosis, and is used in the study of diabetes, diabetic nephropathy (DN), obesity, and nonalcoholic fatty liver disease (NAFLD). price>
R-OR-320 Polyglycine,CAS:25718-94-9 Polyglycine,CAS:25718-94-9 Polyglycine,CAS:25718-94-9 from ruixi Polyglycine is a substance used to modify carbon fiber microelectrode differential pulse voltammetry for the determination of uric acid. It is mainly used in the preparation of synthetic vaccines and as a biochemical material to study the physical and chemical properties of polypeptide compounds, such as conformational types and reaction characteristics in water environment. price>
R-mo-287 CCOF-5,Chiral covalent organic frameworks-5 CCOF-5,Chiral covalent organic frameworks-5 from ruixi.CCOF was synthesized from chiral taddol precursor with helical structure and diamine precursor with flexible structure. It is a covalent organic framework material with double interpenetrating network.Ccof-5 has separation performance,it can be used as a chiral stationary phase for the separation of racemic alcohols. price>
R-R-1421 USP7-IN-9 USP7-IN-9 is a highly potent ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 value of 40.8 nM. USP7-IN-9 can induce apoptosis and arrest cell progression at G0/G1 and S phases in RS4; 11 cells. USP7-IN-9 reduces the protein levels of oncoproteins MDM2 and DNMT1 and increases the protein levels of tumor suppressors p53 and p21. price>
R-OR-321 Poly-L-arginine hydrochloride ,CAS:26982-20-7 Poly-L-arginine hydrochloride ,CAS:26982-20-7 Poly-L-arginine hydrochloride ,CAS:26982-20-7 from ruixi Poly-L-arginine hydrochloride is a positively charged synthetic polyamino acid having one HCl per arginine unit. It is a crystalline solid soluble in water. Applications for poly-L-arginine hydrochloride include the layer-by-layer deposition techniques and the complexation with nucleic acids for gene expression. price>
R-mo-288 CCOF-6,Chiral covalent organic frameworks-6 CCOF-6, Chiral covalent organic frameworks-6 from ruixi.CCOF was synthesized from chiral taddol precursor with helical structure and diamine precursor with flexible structure. It is a covalent organic framework material with double interpenetrating network.CCOF-6 has separation performance,can be used as a chiral stationary phase for the separation of racemic alcohols. price>
R-R-1422 PF-543 Citrate CAS No.1415562-83-2 PF-543 Citrate (Sphingosine Kinase 1 Inhibitor II Citrate)/CAS No.1415562-83-2 is a potent, selective, reversible and sphingosine-competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3.6 nM. PF-543 Citrate is >100-fold selectivity for SPHK1 over SPHK2. PF-543 Citrate is an effective potent inhibitor of sphingosine 1-phosphate (S1P) formation in whole blood with an IC50 of 26.7 nM. PF-543 Citrate induces apoptosis, necrosis, and autophagy. price>
R-OR-322 Poly-DL-alanine ,CAS: 25281-63-4 Poly-DL-alanine ,CAS: 25281-63-4 Poly-DL-alanine ,CAS: 25281-63-4 from ruixi The Raman spectrum of poly‐DL‐alanine (PDLA) in the solid state is interpreted in terms of the disordered chain conformation, in analogy with the spectrum of mechanically deformed poly‐L‐alanine. The polymer is largely disordered with only a small α‐helical content in the solid state. When PDLA is dissolved in water, the spectra suggest that short α‐helical segments are formed upon dissolution. These helical regions might be stabilized by hydrophobic bonds between side‐chain methyl groups. price>
R-mo-289 COF-BPDA,Chiral covalent organic framework-3,3,4,4-biphenyltetracarboxylic dianhydride COF-BPDA,Chiral covalent organic framework-3,3,4,4-biphenyltetracarboxylic dianhydride from ruixi.CCOF was synthesized from chiral taddol precursor with helical structure and diamine precursor with flexible structure. It is a covalent organic framework material with double interpenetrating network. price>
R-R-1423 12-HETE-d8 CAS No.2525175-25-9 12-HETE-d8/CAS No.2525175-25-9 is the deuterium labeled 12-HETE. 12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway.12-HETE has both anti-thrombotic and pro-thrombotic effects. 12-HETE is a neuromodulator. price>
R-OR-323 Poly-L-threonine,CAS:82822-12-6 Poly-L-threonine,CAS:82822-12-6 Poly-L-threonine,CAS:82822-12-6 from ruixi Amino acids, as a kind of very important life substance, are widely used in medicine, biology, chemistry and other fields. Up to now, most of the researches on amino acids have focused on synthesis, characterization and the role in genetic function. price>