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cRIPGBM chloride CAS No.2361988-77-2
cRIPGBM chloride CAS No.2361988-77-2
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-1418 | 25mg | 260.00 | + Add to cart |
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| R-R-1418 | 50mg | 420.00 | + Add to cart |
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Product description
cRIPGBM chloride/CAS No.2361988-77-2, an orally active, proapoptotic derivative. cRIPGBM can be generated from glioblastoma multiforme (GBM) cancer stem cells (CSCs). cRIPGBM(chloride) targets to receptor-interacting protein kinase 2 (RIPK2) to induce caspase 1-dependent apoptosis. cRIPGBM(chloride) suppresses the formation of RIPK2/TAK1 (prosurvival complex), and increases the formation of RIPK2/caspase 1 (proapoptotic complex). cRIPGBM(chloride) exerts potent anti-tumor activity in vivo in animal models.
| Appearance | N/A |
|---|---|
| Molecular Weight | 446.90 |
| Purity | >90% |
| CAS | 2361988-77-2 |
| Formula | C26H20ClFN2O2 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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