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R-R-1389 Tegaserod maleate CAS No.189188-57-6 Tegaserod maleate (SDZ-HTF-919)/CAS No.189188-57-6 is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist. Tegaserod maleate has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod maleate causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. Tegaserod maleate has anti-tumor activity and has the potential for irritable bowel syndrome (IBS) research. price>
R-mo-256 CoF2 CoF2,Cobalt(II) fluoride from ruixi.Cobalt (II) fluoride can be used in organic reaction catalyst, organic fluorination agent and preparation of cobalt trifluoride. price>
R-R-1390 MRT199665 CAS No.1456858-57-3 MRT199665/CAS No.1456858-57-3 is a potent and ATP-competitive, selective MARK/SIK/AMPK inhibitor with IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively. MRT199665 causes apoptosis in MEF2C-activated human acute myeloid leukemias (AML) cells. MRT199665 inhibits the phosphorylation of SIK substrate CRTC3 at S370. price>
R-MF-002 HKUST-1 HKUST-1 Metal organic frame material HKUST-1 from ruixi HKUST-1 is also known as mof-199, Cu BTC and basolite (TM) C300. HKUST-1 is a blue cubic crystal copper based microporous metal framework (MOF). It was prepared by solvothermal method. Its surface area may be close to 2200m2 / G2. price>
R-mo-257 COF-202 COF-202,Covalent organic framework-202 from ruixi.Cof-202 has high thermal stability, low density and high porosity. The design and synthesis of cof-202 expands the type of bond and can be used to crystallize new materials with extended covalent organic frameworks.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications. price>
R-R-1391 Ivaltinostat formic Ivaltinostat (CG-200745) formic is an orally active, potent pan-HDAC inhibitor which has the hydroxamic acid moiety to bind zinc at the bottom of catalytic pocket. Ivaltinostat formic inhibits deacetylation of histone H3 and tubulin. Ivaltinostat formic induces the accumulation of p53, promotes p53-dependent transactivation, and enhances the expression of MDM2 and p21 (Waf1/Cip1) proteins. Ivaltinostat formic enhances the sensitivity of Gemcitabine-resistant cells to Gemcitabine (HY-16138) and 5-Fluorouracil (5-FU; HY-90006). Ivaltinostat formic induces apoptosis and has anti-tumour effects. price>
R-MF177 MOF-177 Metal organic framework material Metal-Organic Frameworks-177 MOF-177 from ruixi Metal organic framework MOF-177 is one of the most promising crystalline porous adsorbents for hydrogen adsorption.MOF-177 has very large pores and can combine the properties of polycyclic organic guest molecules. price>
R-mo-258 COF-42 COF-42,Covalent organic framework-42 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications. price>
R-R-1392 Higenamine hydrochloride CAS No.11041-94-4 Higenamine hydrochloride/CAS No.11041-94-4 is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases. price>
R-MF808 MOF-808 Metal organic framework material Metal-Organic Frameworks-808 MOF-808 from ruixi Mof-808 has high activity of endoperoxidase. Mof-808 can be used for the colorimetric detection of hydrogen peroxide. The detection limit of hydrogen peroxide is 4.5 μ m, and the linear range is 10 μ m ~ 15 mm. price>
R-mo-259 COF-43 COF-43,Covalent organic framework-43 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications. price>
R-R-1393 PCC0208017 CAS No.2623158-64-3 PCC0208017/CAS No.2623158-64-3 is a microtubule affinity regulating kinases (MARK3/MARK4) inhibitor with IC50s of 1.8 and 2.01 nM, respectively. PCC0208017 has much lower inhibitory activity against MARK1 and MARK2, with IC50s of 31.4 and 33.7 nM, respectively. PCC0208017 suppresses glioma progression in vitro and in vivo. PCC0208017 disrupts microtubule dynamics and induces G2/M phase cell cycle arrest and cell apoptosis. PCC0208017 demonstrates robust antitumor activity in vivo and displays good BBB permeability. price>
R-CF510 COF-5 Covalent organic framework-5 Covalent organic framework-5 COF-5 from ruixi Metal–organic frameworks (MOFs) are a class of compounds consisting of metal ions or clusters coordinated to organic ligands to form one-, two-, or three-dimensional structures. They are a subclass of coordination polymers, with the special feature that they are often porous. price>
R-mo-260 COF-316 COF-316, Covalent organic framework-316 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications. price>
R-R-1394 BRD4/CK2-IN-1 CAS No.2756851-99-5 BRD4/CK2-IN-1/CAS No.2756851-99-5 is the first highly effective and oral active dual-target inhibitor of BRD4/CK2 (bromodomain-containing protein 4/casein kinase 2), with IC50s of 180 nM and 230 nM for BRD4 and CK2, respectively. BRD4/CK2-IN-1 has strong anticancer activity without obvious toxicities. BRD4/CK2-IN-1 induces apoptosis and autophagy-associated cell death in triple-negative breast cancer (TNBC). price>
R-OR-207 Oleic acid-Bismuth trisul fide 5nm Oleic acid-Bismuth trisul fide (5nm)Oleic acid-Bismuth trisul fide 5nm from ruixiBismuth sulfide nanoparticles(5nm) modified by oleic acid.The chemical formula of Bismith sulfur is Bi₂S₃/Bismuth sulfide is a kind of direct band gap semiconductor material. Nano bismuth sulfide has a wide application prospect in thermoelectricity, photoelectric, hydrogen storage and gas sensing. Xian Ruixi bio provides oleic acid modified bismuth sulfide nanoparticles price>
R-mo-261 COF-318 COF-318,Covalent organic framework-318 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications. price>
R-R-1395 Karanjin CAS No.521-88-0 Karanjin/CAS No.521-88-0 is an orally active furanoflavonoid which can be isolated from several Leguminosae. Karanjin exhibits evident anti-diabetic, anti-cancer, anti-inflammatory, antioxidant, anticolitis, anti-ulcer, anti-Alzheimer properties and multiple insect repellent/insecticidal, acaricide properties, suggesting the potential of Karanjin to be applied to relevant research. price>
R-OR-208 Mesoporous silica microsphere coating Nanogoldrods,LSPR808nm Mesoporous silica microsphere coating Nano gold rods(LSPR808nm)Mesoporous silica microsphere coating Nano gold rods,LSPR808nm from ruixi Mesoporous silica coated gold nanorods have been widely used in biomedical field due to their unique optical properties, regular pore size, large specific surface area and easy modification. price>
R-mo-262 COF-6 COF-6,Covalent organic framework-6 from ruixi.Covalent organic frameworks (COFS) are a kind of crystalline porous polymers, which can integrate the organic units accurately on the atoms, thus forming the pre designed framework and nano pores. It can be used to design organic materials for gas storage, catalysis and optoelectronic applications.COF-6 is a kind of two-dimensional covalent organic framework material with crystal micropore and mesoporous. Cof-6 has the characteristics of high thermal stability, low density and high porosity. price>