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R-R-1239 Cafestol CAS No.469-83-0 Cafestol, one of the major components of coffee, is a coffee-specific diterpene from. Cafestol/CAS No.469-83-0 is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway. Cafestol contributes to its beneficial effects through various biological activities such as chemopreventive, antitumorigenic, hepatoprotective, antioxidative and antiinflammatory effects. price>
R-PL-0177 Cholesterol-PEG-Benzaldehyde Cholesterol-polyethylene glycol-Benzaldehyde,Cholesterol-PEG-Benzaldehyde from ruixi Cholesterol-PEG-Aacid uses very stable chemical bonds/linkage to attach cholesterol and acid to PEG through ether bond or amide bond. Unlike ester bonds which are prone to hydrolysis in aqueous solution, the ether linkage between cholesterol and PEG is chemically robust and very stable. Cholesterol is a membrane constituent which serves a unique function of modulating membrane fluidity, elasticity, and permeability. It fills in the gaps created by packing of other lipid species when proteins are embedded in the membrane. price>
R-C-242 DSPE-PEG-Xylan DSPE (MPEG DSPE) is a kind of phospholipid peg derivative with terminal DSPE group at PEG end.Xylan is a heterogeneous polysaccharide existing in plant cell wall,accounting for about 15%-35% of plant cell dry weight.Xylan is the main component of plant hemicellulose,and it is a kind of complex pentose. price>
R-R-1240 Anti-inflammatory agent 35 CAS No.2293951-00-3 Anti-inflammatory agent 35 (compound 5a27)/CAS No.2293951-00-3 is an orally active curcumin analogue with anti-inflammatory activity. Anti-inflammatory agent 35 blocks mitogen-activated protein kinase (MAPK) signaling and p65 nuclear translocation of NF-kB. Anti-inflammatory agent 35 also inhibits yellow neutrophil infiltration and pro-inflammatory cytokine production. Anti-inflammatory agent 35 significantly attenuates lipopolysaccharide (LPS)-induced acute lung injury (ALI) in vivo. price>
R-PL-0178 Cholesterol-PEG-LNA Cholesterol-polyethylene glycol-linoleic acid,Cholesterol-PEG-LNA from ruixi Block copolymers Cholesterol-PEG-LNA.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-C-243 DSPE-PEG-Fructan DSPE (MPEG DSPE) is a kind of phospholipid peg derivative with terminal DSPE group at PEG end.Fructosan is a polymer of β-d-fructofuran.Fructosyltransferase catalyzed by sucrose and one or more fructose molecules linked into a water-soluble and viscous polymer polysaccharide. price>
R-R-1241 Enniatin B1 CAS No.19914-20-6 Enniatin B1/CAS No.19914-20-6 is a Fusarium mycotoxin. Enniatin B1 inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 73 μM in an enzyme assay using rat liver microsomes. Enniatin B1 crosss the blood-brain barrier. Enniatin B1 decreases the activation of ERK (p44/p42). Enniatin B1 inhibits moderately TNF-α-induced NF-κB activation. price>
R-PL-0179 Cholesterol-PEG-Mesylate Cholesterol-polyethylene glycol-Mesylate,Cholesterol-PEG-Mesylate from ruixi Block copolymers Cholesterol-PEG-Mesylate.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-C-244 DSPE-PEG-L-Fucose DSPE-PEG-Fucose,DSPE(MPEG DSPE)is a kind of phospholipid peg derivative with terminal DSPE group at PEG end.Fucose is a kind of hexose,also known as 6-deoxy-l-galactose,and can be regarded as a methyl pentose.The majority of fucose in nature is L-fucose,and D-fucose is only found in some sugar glycans as rare sugars.Fucose is less than one hydroxyl group in the sixth carbon atom than the general hexasaccharide,so fucose is less hydrophilic than other monosaccharides,but more hydrophobic. price>
R-R-1242 Diprovocim CAS No.2170867-89-5 Diprovocim/CAS No.2170867-89-5 is a potent TLR1/TLR2 agonist. Diprovocim elicits full agonist activity in human THP-1 cells (EC50=110 pM). Diprovocim stimulates the release of TNF-α from mouse macrophages (EC50=1.3 nM). Diprovocim activates downstream MAPK and NF-κB signaling pathway. Diprovocim displays strong adjuvant activity in mice, particularly abetting cellular immune responses. price>
R-PL-0180 Cholesterol-PEG-TPP Cholesterol-polyethylene glycol-Triphenyl phosphate,Cholesterol-PEG-TPP from ruixi Block copolymers Cholesterol-PEG-TPP.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-C-245 DSPE-PEG-maltose Maltose is a colorless crystal.It usually contains one molecule of crystal water with a melting point of 102 ℃ and soluble in water.There are two isomers of α -and β-maltose.The ratio of α-and β-Maltose in aqueous solution is 42:58.It can be used in various fields such as maltose,liquid food and so on.DSPE (MPEG DSPE)is a kind of phospholipid peg derivative with terminal DSPE group at PEG end. price>
R-R-1243 11-Keto-beta-boswellic acid CAS No.17019-92-0 11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid)/CAS No.17019-92-0 is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense. 11-Keto-beta-boswellic acid has the anti-inflammatory activity is primarily due to inhibit 5-lipoxygenase (5-LOX) and subsequent leukotriene and nuclear factor-kappa B (NF-κB) activation and tumor necrosis factor alpha generation production. price>
R-PL-0181 Cholesterol-PEG-Dopamine Cholesterol-polyethylene glycol-Dopamine,Cholesterol-PEG-Dopamine from ruixi Block copolymers Cholesterol-PEG-Dopamine .Dopamine is an organic chemical of the catecholamine and phenethylamine families. It functions both as a hormone and a neurotransmitter, and plays several important roles in the brain and body. It is an amine synthesized by removing a carboxyl group from a molecule of its precursor chemical L-DOPA. price>
R-C-246 DSPE-PEG-Rhamnose Rhamnolipid is a kind of biosurfactant produced by Pseudomonas or Burkholderia. It is a kind of biosurfactant with the longest research time and the most mature application technology.It exists naturally in soil,water and plants,and belongs to a kind of sugar and lipid anionic surfactant.Rhamnose can be used to measure intestinal permeability,can be used as sweetener,and can also be used to produce flavors and fragrances,edible.DSPE (MPEG DSPE)is a kind of phospholipid peg derivative with terminal DSPE group at PEG end. price>
R-R-1244 Ginsenoside Rg5 CAS No.186763-78-0 Ginsenoside Rg5/CAS No.186763-78-0 is the main component of Red ginseng and IGF-1R agonist. Ginsenoside Rg5 compets for the binding site of IGF-1R and blocks the binding of IGF-1 to IGF-1R (IC50 about 90 nM). Ginsenoside Rg5 also inhibits the mRNA expression of COX-2 via suppression of the DNA binding activities of NF-κB p65. price>
R-PL-0182 Cholesterol-PEG-Ferrocene Cholesterol-polyethylene glycol-Ferrocene,Cholesterol-PEG-Ferrocene from ruixi Block copolymers Cholesterol-PEG-Ferrocene.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-C-247 DSPE-PEG-Cellobiose Cellobiose is the hydrolytic product of cellulose and the basic structural unit of cellulose.Cellobiose is a reducing sugar.DSPE (MPEG DSPE) is a kind of phospholipid peg derivative with terminal DSPE group at PEG end. price>
R-R-1245 S-Allylmercaptocysteine CAS No.2281-22-3 S-allylmercaptocysteine/CAS No.2281-22-3, an organic sulfur compound extracted from garlic, has anti-inflammatory and anti-oxidative effects for various pulmonary diseases. S-allylmercaptocysteine achieves its anti-cancer effect through a variety of pathways such as inducing the apoptosis of cancer cells through the TGF-β signaling pathway, or reducing the NF-κB activity and up-regulating Nrf2 to achieve the effects of anti-inflammation and anti-oxidation. price>
R-PL-0183 Cholesterol-PEG-GA Cholesterol-polyethylene glycol-glycyrrhetinic acid,Cholesterol-PEG-GA from ruixi Block copolymers Cholesterol-PEG-GA.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>