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Catalog	name	Description	price
R-R-1143	Ipatasertib dihydrochloride CAS No.1396257-94-5	Ipatasertib dihydrochloride (GDC-0068 dihydrochloride)/CAS No.1396257-94-5 is a highly selective and ATP-competitive pan-Akt inhibitor with IC50s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively.	price>
R-PL-0105	PCL-PEG-DBCO	poly(ε-caprolactone)-polyethylene glycol--DBCO,PCL-PEG-DBCO from ruixi poly(ε-caprolactone)-polyethylene glycol--DBCO (PCL-PEG-Aminooxy) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-T-890	P2VP-PMMA	Polyvinyl pyridine can be used as paper reinforcing agent,fiber modifier,rubber modifier and raw material of ion exchange resin.Poly (methyl methacrylate)(PMMA),with the advantages of high transparency,low price and easy machining,is often used as a substitute for glass.	price>
R-DS-0050	DSPE-PEG2000-D4	Peptide ligands containing six amino acids were screened for tumor cell epidermal growth factor (EGFR).Fluorescent liposomes containing D4 peptide were injected into tumor bearing mice via tail vein.In vivo imaging of small animals showed that fluorescent liposomes not only accumulated in tumor,but also had strong fluorescence signal in brain.Using loperamide as the"probe"and DSPE-PEG2000-D4 micelles as carriers,we found that D4 peptide has the ability to cross the blood-brain barrier through hot water bath tail contraction and formalin induced pain in mice.	price>
R-R-1144	Pifusertib hydrochloride CAS No.2930090-28-9	Pifusertib (TAS-117) hydrochloride/CAS No.2930090-28-9 is a potent, selective, orally active allosteric Akt inhibitor (with IC50s of 4.8, 1.6, and 44 nM for Akt1, 2, and 3, respectively). Pifusertib hydrochloride triggers anti-myeloma activities and enhances fatal endoplasmic reticulum (ER) stress induced by proteasome inhibition. Pifusertib hydrochloride induces apoptosis and autophagy.	price>
R-PL-0106	PCL-PEG-TCO	poly(ε-caprolactone)-polyethylene glycol--TCO PCL-PEG-TCO from ruixi poly(ε-caprolactone)-polyethylene glycol--TCO (PCL-PEG-TCO) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-U-678	p2vp-ps-pmma	Polystyrene(PS)is a kind of polymer synthesized by free radical addition polymerization of styrene monomer.Polyvinyl pyridine can be used as paper reinforcing agent,fiber modifier,rubber modifier and raw material of ion exchange resin.Poly (methyl methacrylate)(PMMA),with the advantages of high transparency,low price and easy machining,is often used as a substitute for glass.	price>
R-DS-0051	DSPE-PEG2000-RLT	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.	price>
R-R-1145	Paris saponin VII CAS No.68124-04-9	Paris saponin VII (Chonglou Saponin VII)/CAS No.68124-04-9 is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia.	price>
R-PL-0107	PCL-PEG-TZ	poly(ε-caprolactone)-polyethylene glycol--Tetrazine PCL-PEG-TZ from ruixi poly(ε-caprolactone)-polyethylene glycol--Tetrazine (PCL-PEG-TZ) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-R-2020	m-peg16-acid	The PEG derivatives and small molecule PEG derivatives provided by Ruixi biology are the products synthesized by our own laboratory,with a complete range of products.Can customize a variety of products.	price>
R-DS-0052	DSPE-PEG5000-LTV	On the basis of PL(ID)NP nanoparticles,pl(V/D) np-ltv,a dual-mode CT/fluorescence nanoparticles targeting spontaneous breast cancer,was developed.HER2 targeted nanoparticles pl(I/D) np-ltv were prepared by modifying pl(I/D) NP with targeted phospholipid dspe-peg5000-ltv.The particle size of DLS was 64.9 ± 1.3 nm and had good serum stability.	price>
R-R-1146	CHPG sodium salt CAS No.1303993-73-8	CHPG sodium salt is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. CHPG sodium salt protects against traumatic brain injury (TBI) in vitro and in vivo by activation of the ERK and Akt signaling pathways.	price>
R-PL-0108	4arm/8arm-PCL-PEG	4arm/8arm poly(ε-caprolactone)-polyethylene glycol,4arm/8arm-PCL-PEG from ruixi Multiarm block copolymers 4arm/8arm-PCL-PEG. .The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid.	price>
R-DS-0053	RPAKPAR-PEG-DSPE	A variety of receptors are highly expressed in brain tumor cells and blood-brain barrier,such as transferrin receptor,low-density lipoprotein receptor and so on. Therefore,the specific ligands of these receptors can be used as two-level target molecules for blood-brain barrier and brain tumor cells.	price>
R-R-1147	TD52 CAS No.1798328-24-1	TD52/CAS No.1798328-24-1, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 has less p-EGFR inhibition and has potent anti-cancer activity. TD52 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-PL-0109	PCL-PEG-CHEMS	poly(ε-caprolactone)-polyethylene glycol--CHEMS,PCL-PEG-CHEMS from ruixi poly(ε-caprolactone)-polyethylene glycol--CHEMS (PCL-PEG-CHEMS) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-CMF10050	Fe3O4 Magnetic nanoparticles with FITC coating in water/ Organic	Green fluorescein FITC labeled mesoporous silica coated with magnetic nanoparticles can be used as drug carriers,FITC fluorescence can be used for fluorescence tracking imaging,cell sorting,magnetic targeting hyperthermia, magnetic particle contrast agent,etc.,which belong to dual imaging nano materials.	price>
R-DS-0054	DSPE-PEG2000-NGF	NGF is a kind of polypeptide with various activities,which widely exists in various tissues of animals.It can nourish the injured peripheral nerve and promote regeneration and repair.When the peripheral nerve is injured,its corresponding cell body and axon can use exogenous NGF to transport retrogradely through the injured axon,making NGF reach the corresponding cell body.After the complex process of anabolism,NGF can be extended,It promotes axonal myelination.	price>
R-R-1148	Sophocarpine CAS No.6483-15-4	Sophocarpine/CAS No.6483-15-4 is one of the significant alkaloid extracted from the traditional herb medicine Sophora flavescens which has many pharmacological properties such as anti-virus, anti-tumor, anti-inflammatory. Sophocarpine significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy, activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. Sophocarpine has been demonstrated to have anti-tumor activity in various cancer cells, including hepatocellular carcinoma, prostate cancer and colorectal cancer.	price>

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