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Catalog	name	Description	price
R-DS-0023	DOPE-PEG-polypeptide GE11(YHWYGYTPQNVI）	Peptide GE11 is a small molecular peptide obtained by phage peptide library screening technology.It is composed of 11 amino acids (yhwygytpqnvi).Ge11 modified micelles are targeting EGFR.The results show that the prepared active targeting EGFR micelles accelerate the cell uptake of drugs,and EGFR is overexpressed on the surface of non-small cell lung cancer.GE11,a target peptide of EGFR,has been widely used in tumor targeted delivery of genes and drugs.Phospholipid micelles have good tumor tissue penetration,and the introduction of targeted phospholipid micelles may obtain better drug aggregation effect in tumor tissues.	price>
R-C-015	DSPE-PEG-PCL	PEG-PCL can be used in targeted drug research and widely used in protein carrier and ligand crosslinking. Polyethylene glycol polycaprolactone can be used as drug loaded microspheres,microcapsules,vesicles and micelles,which can be used to achieve sustained and controlled release of drugs,and can also be used as tissue engineering scaffold materials with good hydrophilicity.DSPE (1,2-distearyl-sn-glycerin-3-phosphate ethanolamine) is a saturated 18 carbon phospholipid,which is commonly used in the synthesis of liposomes.Polyethylene glycol (PEG)-coupled DSPE is hydrophilic and can be used for drug delivery,gene transfection and biomolecular modification.The PEGylation of phospholipids significantly improved the capsules.	price>
R-R-1214	PI3K-IN-30 CAS No.2281803-22-1	PI3K-IN-30 (compound 6d)/CAS No.2281803-22-1 is a potent PI3K inhibitor with IC50s of 5.1, 136, 30.7 and 8.9 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.	price>
R-PL-0171	DSPE-PEG-ISC	1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-Isocyanate,DSPE-PEG-ISC from ruixi DSPE PEG has both hydrophilicity and hydrophobility and can be used for drug delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs and are the excellent liposome formation materials. These liposomes can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.	price>
R-DS-0024	PLGA-PEG-polypeptide GE11(YHWYGYTPQNVI）	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.	price>
R-C-016	DSPE-PEG-PLA	PEG-PLA can be used in the research of targeted drugs and the crosslinking of protein carriers and ligands.Polyethylene glycol polylactic acid can be used as drug loaded microspheres,microcapsules,vesicles and micelles,which can be used to achieve drug sustained-release and controlled-release.It can also be used as a tissue engineering scaffold with good hydrophilicity.DSPE(1,2-distearyl-sn-glycerin-3-phosphate ethanolamine) is a saturated 18 carbon phospholipid,which is commonly used in the synthesis of liposomes.Polyethylene glycol (PEG) - coupled DSPE is hydrophilic and can be used for drug delivery,gene transfection and biomolecular modification.	price>
R-R-1215	Buparlisib Hydrochloride CAS No.1312445-63-8	Buparlisib Hydrochloride (BKM120 Hydrochloride)/CAS No.1312445-63-8 is a pan-class I PI3K inhibitor, with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively.	price>
R-PL-0172	Cholesterol-PEG-Phenyl	Cholesterol-polyethylene glycol-Phenyl,Cholesterol-PEG-Phenyl from ruixi Cholesterol is one of the important constituent of all membranes. It is made up of a hydrophobic, planar, a polar hydroxyl group, fused-ring nucleus and a short hydrocarbon tail.	price>
R-DS-0025	PCL-PEG-polypeptide GE11(YHWYGYTPQNVI）	Poly(ε-caprolactone)-Polyethylene glycol-polypeptide GE11(YHWYGYTPQNVI） ,GE11,a target peptide of EGFR,has been widely used in tumor targeted delivery of genes and drugs.Phospholipid micelles have good tumor tissue penetration,and the introduction of targeted p.hospholipid micelles may obtain better drug aggregation effect in tumor tissues.Peptide GE11 is a small molecular peptide obtained by phage peptide library screening technology.It is composed of 11 amino acids (yhwygytpqnvi).The results showed that EGFR was over expressed on the surface of NSCLC.	price>
R-C-012	DSPE-PEG-nano gold	Polyethylene glycol polylactic acid can be used as drug loaded microspheres, microcapsules,vesicles and micelles,which can be used to achieve drug sustained-release and controlled-release.It can also be used as a tissue engineering scaffold with good hydrophilicity.Polyethylene glycol(PEG)-coupled DSPE is hydrophilic and can be used for drug delivery,gene transfection and biomolecular modification.Gold nanoparticles are the tiny particles of gold,which have high electron density,dielectric properties and catalysis.They can combine with a variety of biological macromolecules without affecting their biological activities.Gold nanoparticles with different particle sizes can be easily prepared by reduction of chloroauric acid.The color of gold nanoparticles varies from red to purple according to the diameter.	price>
R-R-1216	Vps34-IN-2 CAS No.1523404-29-6	Vps34-IN-2/CAS No.1523404-29-6 is a novel, potent and selective inhibitor of Vps34 with IC50s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively. Vps34-IN-2 shows antiviral activity against SARS-CoV-2 (IC50 of 3.1 μM), HCoV-229E (IC50 of 0.7 μM) and HCoV-OC43.	price>
R-PN-002	4-arm-PLGA-MAL	4 arm-Poly(D,L-lactide-co-glycolide)-Maleimide, 4-arm-PLGA-MAL from ruixi.Maleimide capped 4-arm poly(lactide-co-glycolide) (4-arm PLGA-Maleimide, 4-arm PLGA-Mal) is a multiarm PLGA derivative with amine groups at each terminal of the four arms connected to one pentaerythritol core. The maleimide group selectively reacts with free thiol, SH, sulfhydryl, or mercapto group via Michael addition to form a stable carbon sulfur bond. 4-Arm PEG-MAL can be used for site specific protein and peptide modification.	price>
R-DS-0026	PLA-PEG-polypeptide GE11(YHWYGYTPQNVI）	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.As active targeting materials,therapeutic materials or adjuvant therapeutic materials,ruixibio can synthesize various kinds of polypeptide polyethylene glycol(PEG)-PLA reagents,which are widely used in scientific research.	price>
R-C-9957	DSPE-PEG2000-Galactose	Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery.Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation.These materials can also be used for targeted drug delivery by modifying surface ligands such as antibodies and peptides.Pegylated galactose has better water solubility and other enhanced properties.Galactose,a monosaccharide group,greatly improves the selectivity of PEGylation.We can provide peg molecular weights of 1k, 2k, 3.4k, 5k, and 10k for this product	price>
R-R-1217	iMDK quarterhydrate	iMDK quarterhydrate is a potent PI3K inhibitor and inhibits the growth factor MDK (also known as midkine or MK). iMDK quarterhydrate suppresses non-small cell lung cancer (NSCLC) cooperatively with A MEK inhibitor without harming normal cells and mice.	price>
R-PN-003	4-arm-PLGA-SH	4 arm-Poly(D,L-lactide-co-glycolide)-thiol,4-arm-PLGA-SH from ruixi.4-arm poly(lactide-co-glycolide) (4-arm PLGA) is a multiarm PLGA connected to one pentaerythritol core. 4-arm PLGA is terminated with hydroxyl group for further modification.	price>
R-DS-01	Phospholipid-PEG-cluster peptide	Phospholipid,also known as phospholipids and phospholipids,refers to lipids containing phosphoric acid,belonging to compound lipids.Polyethylene glycol is a kind of compound.Its series of products have no irritation,slight bitter taste,good water solubility and good compatibility with many organic components.	price>
R-C-040	DSPE-PEG-Tetrazine	Tetrazine can be used for biorthogonal reactions in many bioimaging and conjugation applications.At present,it is widely used in protein specific site function interpretation,subcellular structure selective labeling,drug targeted delivery,in vivo animal molecular imaging and preparation of biocompatible materials.Polyethylene glycol phospholipid liposomes form high-quality materials, which can be used for drug delivery,gene transfection and vaccine delivery. Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation.These materials can also be used for targeted drug delivery by modifying surface ligands such as antibodies and peptides.	price>
R-R-1218	Tenalisib CAS No.1639417-53-0	Tenalisib (RP6530)/CAS No.1639417-53-0 is a novel, potent, and selective PI3Kδ and PI3Kγ inhibitor with IC50 values of 25 and 33 nM, respectively.	price>
R-PN-004	4-arm-PLGA-NHS	4 arm-Poly(D,L-lactide-co-glycolide)-N-Hydroxysuccinimide ,4-arm-PLGA-NHS from ruixi.4-arm poly(lactide-co-glycolide) (4-arm PLGA) is a multiarm PLGA connected to one pentaerythritol core. 4-arm PLGA is terminated with hydroxyl group for further modification.	price>

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