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Catalog	name	Description	price
R-PL1311-X	PAMAM-PEG-SH	PAMAM-polyethylene glycol-Thiol,PAMAM-PEG-SH from ruixi PAMAM-polyethylene glycol-Thiol(PAMAM-PEG-Thiol)is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-DS-0004	DSPE-PEG-TH(AGYLLGHINLHHLAHL)	A pH responsive cell penetrating peptide modified liposome th lip was synthesized by introducing th into liposomes.Due to the pH sensitivity of th, the transmembrane activity of th is masked in blood circulation and normal tissues;when th lip reaches tumor tissue,histidine in th sequence is protonated, which makes the surface charge of th lip turn from negative to positive, and the transmembrane activity of th is activated,which increases the uptake of th lip by tumor cells.In vitro studies showed that paclitaxel loaded liposome PTX th lip could effectively inhibit the growth of tumor cells and induce apoptosis in a pH dependent manner.	price>
R-DS-0091	DMPE-PEG5000-pCF1-CFTR	DMPE is commonly used in the synthesis of liposomes.Polyethylene glycol (PEG)-coupled DSPE is hydrophilic and can be used for drug delivery,gene transfection and biomolecular modification.PEGylation of phospholipid significantly improved the blood circulation time and stability of capsule drugs.Polyethylene glycol can enhance solubility and stability,reduce the surface nonspecific binding of charged molecules,and reduce the immunogenicity of peptides.	price>
R-R-1185	Idelalisib-d5 CAS No.1830330-31-8	Idelalisib-d5/CAS No.1830330-31-8 is a deuterium labeled Idelalisib. Idelalisib is a highly selective and orally bioavailable p110δ inhibitor.	price>
R-PL1303-X	PAMAM-PEG-Biotin	PAMAM-polyethylene glycol-Biotin,PAMAM-PEG-Biotin from ruixi PAMAM-polyethylene glycol-Biotin (PAMAM-PEG-Biotin )is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-DS-0005	DSPE-PEG-MPG(AGYLLGHINLHHLAHL)	A pH responsive cell penetrating peptide modified liposome th lip was designed and synthesized by introducing th into liposomes.Due to the pH sensitivity of th,the transmembrane activity of th is masked in blood circulation and normal tissues;when th lip reaches tumor tissue,histidine in th sequence is protonated,which makes the surface charge of th lip turn from negative to positive,and the transmembrane activity of th is activated,which increases the uptake of th lip by tumor cells.	price>
R-DS-0092	DSPE-PEG-CSF	DSPE-PEG peptide customization/phospholipid service Ruixi Biotechnology Co.,Ltd. is a well-known phospholipid and PEG phospholipid supplier in China.Our laboratory has been committed to developing more dspe-peg-x derivatives.DSPE-PEG is a kind of long-term liposome material.It is modified with various active targeting materials or therapeutic materials or adjuvant treatment materials at the end of PEG,which is widely used in scientific research In the field.	price>
R-R-1186	Parsaclisib hydrochloride CAS No.1995889-48-9	Parsaclisib hydrochloride (INCB050465 hydrochloride)/CAS No.1995889-48-9 is a potent, selective and orally active inhibitor of PI3Kδ, with an IC50 of 1 nM at 1 mM ATP. Parsaclisib hydrochloride shows approximately 20000-fold selectivity over other PI3K class I isoforms. Parsaclisib hydrochloride can be used for the research of relapsed or refractory B-cell malignancies.	price>
R-PL-0143	PNIPAAm-PEG-NH2	POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Amine,PNIPAAm-PEG-NH2 from ruixi POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Amine(PNIPAAm-PEG-Biotin )is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-DS-0006	DSPE-PEG-SEARYL-R8	1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Polyethylene glycol-SEARYL-R8 ,Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.	price>
R-DS-0093	DSPE-PEG-An1	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.	price>
R-R-1187	Pilaralisib analogue CAS No.956958-53-5	Pilaralisib analogue (XL147 analogue)/CAS No.956958-53-5 is a representative and selective PI3Kα inhibitor extracted from patent WO2012006552A1, Compound 147 in Table 1.	price>
R-PL-0144	PNIPAAm-PEG-COOH	POLY(N-ISOPROPYL ACRYL-polyethylene glycol-carboxyl,PNIPAAm-PEG-COOH from ruixi POLY(N-ISOPROPYL ACRYL-polyethylene glycol-carboxyl (PNIPAAm-PEG-COOH )is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-DS-0007	DSPE-PEG-EB1	Liposomes have the advantages of low toxicity,easy preparation,being both the carrier of water-soluble drugs and the carrier of liposoluble drugs,suitable for various drug delivery routes,improving the stability of drugs and achieving targeted drug delivery.However,when liposomes enter the body,due to the specific regulation of plasma conditioner on liposomes,and the nonspecific hydrophobic effect between the cells of the reticuloendothelial system (RES) and liposomes, it is easy to be absorbed and removed by res cells.The half-life of the liposomes is shorter (generally 30 minutes),and the active targeting and stability are poor,Its application is limited to improve its stability in blood circulation,change the biological distribution of liposomes,and have targeted.	price>
R-DS-0094	DSPE-PEG-RMP-7(receptor-mediated permeabilizer-7)	Bradykinin or RMP-7 can not only increase the transport of anticancer drugs,but also promote gene therapy virus, non viral vector,cytokines into human brain tumor tissue,and improve the lethality of tumor cells and tumor cells in the surrounding infiltration area.Bradykinin or RMP-7 not only can selectively open BTB, but also can promote the peripheral opioid receptor agonist loperamide to pass through the normal BBB to produce central analgesic effect.In the animal model of Parkinson disease,RMP-7 can promote cyclosporine A to pass through the blood-brain barrier and make a small dose of cyclosporine A (CSA) produce neuroprotective effect.	price>
R-R-1188	Roginolisib hemifumarate CAS No.1621688-31-0	Roginolisib (MSC2360844) hemifumarate/CAS No.1621688-31-0 is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. Roginolisib hemifumarate shows highly selective against a panel of 278 additional kinases.	price>
R-PL-0145	PNIPAAm-PEG-MAl	POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Maleimide,PNIPAAm-PEG-MAl from ruixi POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Maleimide(PNIPAAm-PEG-MAl )is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-DS-0008	DSPE-PEG-PF6	(DSPE) conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol,which has hydrophilicity and hydrophobicity.Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery.These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides.One of the important characteristics of cell penetrating peptides (CPPS) is that they can carry a variety of bioactive substances with different sizes and properties into cells,including small molecule compounds,dyes,chromatography,nucleic acids (peptide nucleic acids, PNA),proteins,plasmid DNA,siRNA,200 nm liposomes,phage particles and superparamagnetic particles.	price>
R-DS-0095	DSPE-PEG2000-B6	Cell penetrating peptide (CPP) is a kind of short peptide with strong penetration effect on cell membrane,which can promote cell uptake.Liposome modified by CPP can improve the rate of liposome entry into the cell,which is a new direction of targeted drug delivery carrier research.The amphiphilic block lipid molecule dspe-peg2000-b6 modified by cell osmotic peptide B6 prolonged the blood circulation time,promoted the penetration of nanoparticles (NPS) through BBB,and effectively enriched the drug loaded NPs in glioma lesions.	price>
R-R-1189	PI3Kα-IN-9 CAS No.2715287-67-3	PI3Kα-IN-9 (compound 27)/CAS No.2715287-67-3 is a selective, long-acting and oral active PI3Kα inhibitor with IC50 values of 4.4, 128, 146 and 153 nM for PI3Kα, PI3Kγ, PI3Kδ and PI3Kβ, respectively. PI3Kα-IN-9 has antiproliferative activity and induces apoptosis. PI3Kα-IN-9 can be used for cancer research.	price>

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