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R-FAM-014 5-FITC-Tetrazine Tetrazine can be used for biorthogonal reactions in many bioimaging and conjugation applications.At present,it has been widely used in protein specific site function interpretation,subcellular structure selective labeling,drug targeted delivery,in vivo animal molecular imaging and preparation of biocompatible materials. price>
R-R-1097 Licoricidin CAS No.30508-27-1 Licoricidin (LCD)/CAS No.30508-27-1 is isolated from Glycyrrhiza uralensis Fisch, possesses anti-cancer activities. Licoricidin (LCD) inhibit SW480 cells (IC50=7.2 μM) by inducing cycle arrest, apoptosis and autophagy, and is a potential chemopreventive or chemotherapeutic agent against colorectal cancer. Licoricidin (LCD) inhibits Lung Metastasis by inhibition of tumor angiogenesis and lymphangiogenesis as well as changes in the local microenvironment of tumor tissues the anticarcinogenic effect. Licoricidin enhanced gemcitabine-induced cytotoxicity in Osteosarcoma (OS) cells by inactivation of the Akt and NF-κB pathways in vitro and in vivo. Licoricidin blocks UVA-induced photoaging via ROS scavenging, limits the activity of MMP-1, it can be considered as an active ingredient in new topically applied anti-ageing formulations. price>
R-PL-0065 PIB-b-PMMA Poly(isobutylene-b-methyl methacrylate) PIB-b-PMMA PMMA-b-PIB from ruixi Amphiphilic block copolymer PIB-b-PMMA.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-FAM-015 5-diacetate FAM DBCO Ruixi Biotechnology Co., Ltd.is a well-known biotechnology company in China.At present,its products mainly include synthetic phospholipids,PEG derivatives, block copolymers,gold nanoparticles,magnetic nanoparticles,mesoporous silica, reactive fluorescent dyes,fluorescent quantum dots,dot chemistry and macrocyclic ligands,etc. price>
R-R-1098 TD52 dihydrochloride TD52 dihydrochloride, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 dihydrochloride mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 dihydrochloride indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 dihydrochloride has less p-EGFR inhibition and has potent anti-cancer activity. TD52 (dihydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. price>
R-PL-0066 PIB-b-PDMS Poly(isobutylene-b-dimethylsiloxane) PIB-b-PDMS PDMS-b-PIB from ruixi Amphiphilic block copolymer PIB-b-PDMS.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-FAM-016 5-FAM hydrazide HCl Many natural and synthetic molecules contain aldehydes or ketone carbonyls. These carbonyls react with hydrazides to form hydrazones.When the pH value is neutral,the reaction is spontaneous and the hydrazone is very stable.Fam hydrazide is a hydrazide label used to attach fluorescein (a bright dye with 488 nm channel) to carbonyl compounds.We can provide 5-fam hydrazide HCl. price>
R-R-1099 YS-49 monohydrate YS-49 (monohydrate) is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibits angiotensin II (Ang II)-stimulated proliferation of VSMCs via induction of heme oxygenase (HO)-1. YS-49 is also an isoquinoline compound alkaloid, has a strong positive inotropic action through activation of cardiac β-adrenoceptors. price>
R-PL-0067 PIB-b-PCL Poly(isobutylene-b-ε-caprolactone) PIB-b-PCL PCL-b-PIB from ruixi Amphiphilic block copolymer PIB-b-PCL.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-FAM-017 5-FAM DBCO Fluorescein (FAM) is one of the oldest fluorescent dyes.The derivatives of fam contain cyclooctynyl (dibenzocyclooctyne, abbreviated as dbco or adibo),which are used for conjugation of azides with copper free,strain promoted cycloaddition (spaac).Fam-dbco can be used to label proteins,peptides,nucleic acids and other molecules containing azide groups.Azide reacts spontaneously with dbco after simple mixing.This reaction does not need any catalyst and is highly efficient. price>
R-R-1100 24-Methylenecycloartanyl ferulate CAS No.469-36-3 24-Methylenecycloartanyl ferulate/CAS No.469-36-3 is a γ-oryzanol compound. 24-Methylenecycloartanyl ferulate promotes parvin-beta expression in human breast cancer cells. 24-Methylenecycloartanyl ferulate is a potential ATP-competitive Akt1 inhibitor (EC50= 33.3μM). price>
R-PL-0068 PIB-b-P4VP Poly(isobutylene-b-poly(4-vinyl pyridine) PIB-b-P4VP P4VP-b-PIB from ruixi Amphiphilic block copolymer PIB-b-P4VP.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-FAM-018 Cellhunt Green CMFDA[5-Chloromethylfluorescein Diacetate] Cell-permeable green fluorescent dye.Does not affect cell viability or proliferation.Transforms intracellularly into a cell-impermeant,fluorescent product.Displays fluorescence for at least 72 hours.Brightly fluorescent,non-toxic and stable at physiological pH.Allows for multigenerational tracking of cellular movements. price>
R-R-1101 MPT0E028 CAS No.1338320-94-7 MPT0E028/CAS No.1338320-94-7 is an orally active and selective HDAC inhibitor with IC50s of 53.0 nM, 106.2 nM, 29.5 nM for HDAC1, HDAC2 and HDAC6, respectively. MPT0E028 reduces the viability of B-cell lymphomas by inducing apoptosis and possesses potent direct Akt targeting ability and reduces Akt phosphorylation in B-cell lymphoma. MPT0E028 has good anticancer activity. price>
R-PL-0069 PS-b-PBPA Poly(styrene-b-benzyl propylacrylate) PS-b-PBPA PBPA-b-PS from ruixi Amphiphilic block copolymer PS-b-PBPA.The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-FAM-019 4,5-Diaminofluorescein-Isopropanol adduct (1:2) Fluorescence detector for nitric oxide in culture medium,tissue section and biopsy cells.Ruixi can provide such products 4,5-Diaminofluorescein-Isopropanol adduct (1:2). price>
R-R-1102 CCT128930 hydrochloride CAS No.2453324-32-6 CCT128930 hydrochloride/CAS No.2453324-32-6 is a potent and selective inhibitor of AKT (IC50=6 nM). CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50=168 nM) through the targeting of Met282 of AKT (Met173 of PKA-AKT chimera), as well as 20-fold selectivity over p70S6K (IC50=120 nM). CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. Antitumor activity. price>
R-PL-0070 P2VP-PAA Poly(2-vinyl pyridine)-b-poly(adipic anhydride) P2VP-PAA PAA-P2VP from ruixi Amphiphilic block copolymer P2VP-PAA .The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. price>
R-FAM-020 5-FITC-PEG5-COOH 5-FITC-PEG5-COOH can be provided by ruixi.Fluorescein polyethylene glycol carboxyl group is a linear heterobifunctional peg with fluorescein dye and carboxylic acid group.Fluorescein,commonly known as FITC,is a common fluorescent tracer used to stain cells,tissues,biomarkers or nanoparticles in biology.Fluorescent peg is usually used to label biomolecules and nanoparticles with pegylated dyes and tracers. price>
R-R-1103 CMX-2043 CAS No.910627-26-8 CMX-2043/CAS No.910627-26-8 is a novel analogue of α-Lipoic Acid (HY-N0492). CMX-2043 is effective in antioxidant effect, activation of insulin receptor kinase, soluble tyrosine kinase, and Akt phosphorylation. CMX-2043 shows protection against ischemia-reperfusion injury (IRI) in rat model. price>