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R-R-1188 Roginolisib hemifumarate CAS No.1621688-31-0 Roginolisib (MSC2360844) hemifumarate/CAS No.1621688-31-0 is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. Roginolisib hemifumarate shows highly selective against a panel of 278 additional kinases. price>
R-PL-0145 PNIPAAm-PEG-MAl POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Maleimide,PNIPAAm-PEG-MAl from ruixi POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Maleimide(PNIPAAm-PEG-MAl )is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. price>
R-DS-0008 DSPE-PEG-PF6 (DSPE) conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol,which has hydrophilicity and hydrophobicity.Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery.These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides.One of the important characteristics of cell penetrating peptides (CPPS) is that they can carry a variety of bioactive substances with different sizes and properties into cells,including small molecule compounds,dyes,chromatography,nucleic acids (peptide nucleic acids, PNA),proteins,plasmid DNA,siRNA,200 nm liposomes,phage particles and superparamagnetic particles. price>
R-DS-0095 DSPE-PEG2000-B6 Cell penetrating peptide (CPP) is a kind of short peptide with strong penetration effect on cell membrane,which can promote cell uptake.Liposome modified by CPP can improve the rate of liposome entry into the cell,which is a new direction of targeted drug delivery carrier research.The amphiphilic block lipid molecule dspe-peg2000-b6 modified by cell osmotic peptide B6 prolonged the blood circulation time,promoted the penetration of nanoparticles (NPS) through BBB,and effectively enriched the drug loaded NPs in glioma lesions. price>
R-R-1189 PI3Kα-IN-9 CAS No.2715287-67-3 PI3Kα-IN-9 (compound 27)/CAS No.2715287-67-3 is a selective, long-acting and oral active PI3Kα inhibitor with IC50 values of 4.4, 128, 146 and 153 nM for PI3Kα, PI3Kγ, PI3Kδ and PI3Kβ, respectively. PI3Kα-IN-9 has antiproliferative activity and induces apoptosis. PI3Kα-IN-9 can be used for cancer research. price>
R-PL-0146 PNIPAAm-PEG-NHS POLY(N-ISOPROPYL ACRYL-polyethylene glycol-N-Hydroxysuccinimide,PNIPAAm-PEG-NHS from ruixi POLY(N-ISOPROPYL ACRYL-polyethylene glycol-N-Hydroxysuccinimide (PNIPAAm-PEG-NHS )is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. price>
R-DS-0009 DSPE-PEG-NGR(Asn-Gly-Arg) Aminopeptidase N is a protease preferentially expressed in vascular endothelial cells.NgR sequence can promote the binding of peptide to aminopeptidase N. price>
R-DS-0096 LCDX-PEG-DSPE DSPE-PEG peptide customization-phospholipid service Ruixi Biotechnology Co.,Ltd. is a well-known phospholipid and PEG phospholipid supplier in China.Our laboratory has been committed to developing more dspe-peg-x derivatives.DSPE-PEG is a kind of long-term liposome material.It is modified with various active targeting materials or therapeutic materials or adjuvant treatment materials at the end of PEG,which is widely used in scientific research In the field. price>
R-R-1190 NVS-PI3-4 CAS No.941580-60-5 NVS-PI3-4/CAS No.941580-60-5 is a specific PI3Kγ inhibitor. NVS-PI3-4 can be used for the research of allergies, inflammatory and cancer diseases. price>
R-PL-0147 PNIPAAm-PEG-N3 POLY(N-ISOPROPYL ACRYL-polyethylene glycol-azide,PNIPAAm-PEG-N3 from ruixi POLY(N-ISOPROPYL ACRYL-polyethylene glycol-azide(PNIPAAm-PEG-N3)is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. price>
R-DS-0010 DSPE-PEG-APRPG(ALA Pro Arg Pro Gly) 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Polyethylene glyco-APRPG(ALA Pro Arg Pro Gly),APRPG(ALA Pro Arg Pro Gly),namely alanine proline arginine proline glycine sequence,can specifically act on the neovascularization site of tumor,and can be used as a probe to actively target the neovascularization.Aprpg modified liposomes are beneficial to deliver the encapsulated drugs to the vasculogenic vasculature system.The anti-tumor angiogenesis therapy with aprpg modified liposome can target almost all solid tumors actively without drug tolerance.It is a new and efficient anti-tumor method. price>
R-DS-0097 HE2-PEG2000-DSPE DSPE-PEG peptide customization-phospholipid service Ruixi Biotechnology Co.,Ltd. is a well-known phospholipid and PEG phospholipid supplier in China. Our laboratory has been committed to developing more dspe-peg-x derivatives.DSPE-PEG is a kind of long-term liposome material.It is modified with various active targeting materials or therapeutic materials or adjuvant treatment materials at the end of PEG,which is widely used in scientific research In the field. price>
R-R-1191 Methyllucidone CAS No.19956-54-8 Methyllucidone/CAS No.19956-54-8 is a neuroprotective agent and an antioxidant that can be isolated from Lindera erythrocarpa Makino. Methyllucidone inhibits the ROS production, and activates antioxidant signaling pathways that include Nrf-2 and PI3K. price>
R-PL-0148 PNIPAAm-PEG-Alkyne POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Alkyne,PNIPAAm-PEG-Alkyne from ruixi POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Alkyne (PNIPAAm-PEG-Alkyne)is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. price>
R-DS-0011 DSPE-PEG-VIP(vasoactive intestinal peptide) Vasoactive intestinal peptide (VIP) is a basic peptide composed of 28 amino acid residues.It belongs to the gastrin/VIP family of gastrointestinal peptide hormones.It is widely distributed in the body,and has high content in the gastrointestinal tract,central and peripheral nerve endings,and has a wide range of physiological functions. price>
R-DS-0098 DSPE-PEG-FGF-21 A modified human FGF-21 polypeptide consists of SEQ ID No: 1,SEQ ID No: 2,SEQ ID No: 3,SEQ ID No: 4 with methionine fused at the N-terminal,SEQ ID No: 5,SEQ ID No: 6 or SEQ ID with methionine fused at the N-terminal The modified human FGF-21 peptide has the biological activity of at least one FGF-21,and the unnatural coding amino acid is selected from para substituted phenylalanine,ortho substituted phenylalanine and meta substituted phenylalanine. price>
R-R-1192 CAL-130 Hydrochloride CAS No.1431697-78-7 CAL-130 Hydrochloride/CAS No.1431697-78-7 is a PI3Kδ and PI3Kγ inhibitor with IC50s of 1.3 and 6.1 nM, respectively. price>
R-PL-0149 PNIPAAm-PEG-SH POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Thiol,PNIPAAm-PEG-SH from ruixi POLY(N-ISOPROPYL ACRYL-polyethylene glycol-Thiol (PNIPAAm-PEG-SH)is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. price>
R-DS-1111 DSPE-PEG-PTP(KTLLPTP) PTP (ktllptp) specifically binds to pancreatic cancer cells.Proteomic analysis showed that PTP was targeted by specifically binding to plectin-1,which was mistakenly located on the cell membrane surface during the occurrence of pancreatic cancer. price>
R-DS-0099 DSPE-PEG-ApoL1 APOL1 encodes a secreted high density lipoprotein(apolipoprotein L1) which binds to apolipoprotein A-I.Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL.It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body,as well as in reverse cholesterol transport from peripheral cells to the liver.Several different transcript variants encoding different isoforms have been found for APOL1. price>