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Catalog	name	Description	price
R-TD-0010	W-QDs	The water-soluble quantum dots,which are chemically modified,have good biocompatibility,can be connected specifically,and have little harm to organism,and can be labeled and detected in vivo.Fluorescent dyes are generally toxic and biocompatibility is poor.	price>
R-DS-0069	DA7R-PEG-DSPE	After doxorubicin was loaded,MC-DA7R-PEG-DSPE liposomes could effectively inhibit tumor angiogenesis and pseudo angiogenesis,promote apoptosis of glioma cells,and reduce the number of glioma stem cells,thus enhancing the anti glioma effect of doxorubicin.The median survival time of the model animals was longer than that of single targeted molecular modified liposomes (MC-PEG-DSPE liposome and DA7R-PEG-DSPE liposome) 63.6% and 38.5% respectively.	price>
R-R-1163	Pichromene CAS No.883046-50-2	Pichromene (S14161)/CAS No.883046-50-2 is an anticancer agent and weak PI3K inhibitor. Pichromene can effectively inhibit tumor growth in leukemia mouse models and can be used in cancer research.	price>
R-PL-0125	PAA-PEG-Biotin	Polyacrylic acid-polyethylene glycol-Biotin,PAA-PEG-Biotin from ruixi Polyacrylic acid-polyethylene glycol-Biotin(PAA-PEG-Biotin) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-CD-002	DBCO-C4-NHS Ester	DBCO-C4-NHS Ester is an amine-reactive building block used for modification of amine-containing molecule in organic media.The extended 4-carbon atom spacer arm drastically improves solubility of this reagent in commonly used organic solvents such as dichloromethane, chloroform,THF,and ethyl acetate.In addition extended spacer arm significantly improves derivatization efficiency and stability of conjugates.	price>
R-DS-0070	DSPE-PEG-M2pep(YEQDPWGVKWWY)	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.The liposome can not stay in the tumor site for a long time after intravenous injection,but the targeted liposome prepared by connecting peptide on the surface of liposome can reach the target site immediately after intravenous injection and stay in the tumor site for a long time. The drug released from the liposome can improve the therapeutic effect of tumor.Polyethylene glycol phospholipid is an excellent material to form liposomes,which can be used for gene transfection, vaccine delivery,drug delivery and targeted drug use.	price>
R-R-1164	Umbralisib R-enantiomer CAS No.1532533-69-9	Umbralisib R-enantiomer (TGR-1202 R-enantiomer)/CAS No.1532533-69-9 is a PI3Kδ inhibitor, which is the less active enantiomer of TGR-1202.	price>
R-PL-0126	PAA-PEG-CHO	Polyacrylic acid-polyethylene glycol-aldehyde,PAA-PEG-CHO from ruixi Polyacrylic acid-polyethylene glycol-aldehyde(PAA-PEG-CHO ) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-R1910	RB-PLGA	Rhodamine B is a synthetic dye with bright pink color.It is red to violet powder, blue red in aqueous solution and red in alcohol solution.It is commonly used as a fluorescent staining agent for cells in the laboratory.	price>
R-DS-0071	GLP-1-PEG-DSPE	Glucagon like peptide-1 (GLP-1) is a kind of brain gut peptide secreted by ileal endocrine cells.It is mainly used as the target of type 2 diabetes drugs.PEG modification makes the previously insoluble peptides less soluble and highly mobile.PEG modification can reduce the filtration of drugs by kidney,reduce its pyrogen,reduce the digestion of protease, and enhance its transport capacity by protecting the body immune system.GLP-1 has two Lys located in the inactive site, which provides great flexibility for modification.	price>
R-R-1165	WYE-687 dihydrochloride CAS No.1702364-87-1	WYE-687 dihydrochloride/CAS No.1702364-87-1 is an ATP-competitive mTOR inhibitor with an IC50 of 7 nM. WYE-687 dihydrochloride concurrently inhibits activation of mTORC1 and mTORC2. WYE-687 also inhibits PI3Kα and PI3Kγ with IC50s of 81 nM and 3.11 μM, respectively.	price>
R-PL-0127	PAA-PEG-OPSS	Polyacrylic acid-polyethylene glycol-OPSS，PAA-PEG-OPSS from ruixi Polyacrylic acid-polyethylene glycol-OPSS(PAA-PEG-OPSS) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-DBCO-003	Sulfo CY7-DBCO	Cy7 is a bright and light resistant near-infrared probe.Cy7 dbco is a water-soluble hydrophilic dye.It is usually an analytical reagent that requires minimal nonspecific binding and excellent brightness.The fluorescence of cy7 dbco is not sensitive to pH from pH 4 to pH 10,and the spontaneous fluorescence of biological samples produced in this spectral region is very small.The fluorescence of this long wavelength cyanine dye is invisible to the human eye, but can be easily detected by most imaging systems.	price>
R-DS-0072	HP2-PEG2000-DSPE	HER2,also known as c-erb2,consists of 922 adenine,1382 cytosine,1346 guanine and 880 thymine.HER2 protein mediated signal transduction pathways include Ras/Raf/mitogen activated protein kinase (MAPK),phosphatidylinositol 3-hydroxykinase (PI3K)/Akt pathway,signal transduction and transcriptional activation (STAT) pathway and PLC pathway.	price>
R-R-1166	PI3K-IN-22 CAS No.1202884-94-3	PI3K-IN-22/CAS No.1202884-94-3 is a PI3Kα/mTOR dual kinase inhibitor. PI3K-IN-22 has IC50s of 0.9, 0.6 nM for PI3Kα and mTOR, respectively. PI3K-IN-22 can be used for the research of cancer.	price>
R-PL-0128	PAA-PEG-OH	Polyacrylic acid-polyethylene glycol-hydroxyl，PAA-PEG-OH from ruixi Polyacrylic acid-polyethylene glycol-hydroxyl(PAA-PEG-OH)is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-DBCO-002	Sulfo CY5-DBCO	Cy5 dbco is a kind of azide reaction probe,which is used to image azide labeled biomolecules through copper free click reaction.Dbco partially reacts with azide to form stable triazole,which does not need Cu catalyst or high temperature.The fluorescence probe is water-soluble,and its fluorescence is not sensitive to pH between pH 4 and pH 10.	price>
R-DS-0073	CPPs-PEG-DSPE	Polypeptide modified peg-dspe functional branches were synthesized by the specific reaction between maleimide and thiol group.Targeted CPPs modified nano liposomes were constructed by thin film dispersion method.The physicochemical properties in vitro,including average particle size,surface potential,entrapment efficiency,polydispersity index and in vitro release rate,were studied by laser particle size analyzer and ultraviolet fluorescence spectrophotometry.	price>
R-R-1167	FD223 CAS No.2050524-24-6	FD223/CAS No.2050524-24-6 is a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor. FD223 displays high potency (IC50=1 nM) and good selectivity over other isoforms (IC50s of 51 nM, 29 nM and 37 nM, respectively for α, β and γ). FD223 exhibits efficient inhibition of the proliferation of acute myeloid leukemia (AML) cell lines by suppressing p-AKT Ser473 thus causing G1 phase arrest during the cell cycle. FD223 has potential for the research of leukemia such as AML.	price>
R-PL-0129	PS-PEG-NH2	Polystyrene-polyethylene glycol-Amine,PS-PEG-NH2 from ruixi Polyacrylic acid-polyethylene glycol-Amine(PAA-PEG-NH2 )is a linear A-B-Ctype amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>

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