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Catalog	name	Description	price
R-R-1152	PI3K/AKT-IN-1	PI3K/AKT-IN-1 is an effective PI3K/AKT dual inhibitor (IC50 of 6.99, 4.01 and 3.36 μM for PI3Kγ, PI3Kδ and AKT, respectively). PI3K/AKT-IN-1 has anticancer activity and acts by inhibiting PI3K/AKT axis and inducing caspase 3 dependent apoptosis.	price>
R-PL-0114	PLA-PEG-Tosyl	Poly(D,L-lactide)-polyethylene glycol--Tosylate PLA-PEG-Tosyl from ruixi Poly(D,L-lactide)-polyethylene glycol--Tosylate(PLA-PEG-Tosylate) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-HPPH-1	HPPH	HPPH (photochlor) is a second generation photosensitizer used in photodynamic therapy (PDT).	price>
R-DS-0059	DSPE-PEG3400-SPA	Peptide is a compound formed by α-amino acids linked together by peptide bond, which is the intermediate product of protein hydrolysis.Peptides are widely used in medical research,drug release,nanotechnology and new materials research,cell culture.And the active compounds such as ligand research,peptide synthesis support,graft polymer,new materials and polyethylene glycol modified functional coating.	price>
R-R-1153	3CAI CAS No.28755-03-5	3CAI/CAS No.28755-03-5 is a potent and specific AKT1 and AKT2 inhibitor.	price>
R-PL-0115	PLA-PEG-Acetylthio	Poly(D,L-lactide)-polyethylene glycol--Acetylthio,PLA-PEG-Acetylthio from ruixi Poly(D,L-lactide)-polyethylene glycol--Acetylthio (PLA-PEG-Acetylthio ) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-TH-001	4-thiouridine	4-thiouridine is a photoreactive (cross-linked) uridine analogue,which can be incorporated into RNA structure after phosphorylation to form 4-thioutp.4-thiouridine can be used to study the specificity and kinetics of uridine cytidine kinase.	price>
R-DS-0060	PH1-PEG-DSPE	To verify the potential of targeting distribution of peptide guided liposome drug delivery system,the peptide can be coupled to the polyethylene glycol end of DSPE-PEG through the specific reaction between the sparse group and the maleimide group through the linker SPDP,and the linked products were analyzed by HPLC. We used post insertion technique to combine ph1-peg-dspe micelles with liposomes（ HSPC:Chol Methods:DSPE-PEG=2:1:0.1) were co incubated to prepare targeted liposomes.However,the expression of phe2 in tumor cells was higher by Lipofectamine conjugation and liposome conjugation.Ph1 coupled with cisplatin loaded long circulating liposomes can greatly improve the cytotoxicity of cisplatin liposomes to Tie2 positive cells.	price>
R-R-1154	INY-03-041 CAS No.2503017-97-6	INY-03-041/CAS No.2503017-97-6 is a potent, highly selective and PROTAC-based pan-AKT degrader consisting of the ATP-competitive AKT inhibitor Ipatasertib (HY-15186) conjugated to Lenalidomide (HY-A0003, Cereblon ligand). INY-03-041 inhibits AKT1, AKT2 and AKT3 with IC50s of 2.0, 6.8 and 3.5 nM, respectively.	price>
R-PL-0116	PLA-PEG-Aminooxy	Poly(D,L-lactide)-polyethylene glycol--Aminooxy,PLA-PEG-Aminooxy from ruixi Aminooxy PEG derivatives, also called Oxyamine PEGs, are one of Nanocs aldehyde or ketone reactive PEG derivatives that can react with polysaccharides or glycoproteins. Reaction between aminooxy PEG and aldehyde/ketone forms an oxime bond which can be further reduced by Sodium Borohydride (NaBH4) to form a more stable linkage.	price>
P3556-1G	Phosphatidylcholine(1+)	Phosphatidylcholine belongs to the class of glycerophoshpolipids and contains choline as the head-group.Choline is attached to the glycerol of fatty acids ester-bound to backbone.It is the major phospholipid found in eukaryotic organism.	price>
R-DS-0061	DSPE-PEG-TxID	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.	price>
R-R-1155	KP372-1 CAS No.1374996-60-7	KP372-1/CAS No.1374996-60-7 is an Akt inhibitor that inhibits proliferation and induces apoptosis and anoikis. KP372-1 is also an NQO1 redox cycling agent that causes DNA damage (including DNA breakage) by generating ROS. KP372-1 can be used in cancer research (such as head and neck squamous cell carcinoma (HNSCC) and pancreatic cancer).	price>
R-PL-0117	4arm/8arm-PLA-PEG	4arm/8arm Poly(D,L-lactide)-polyethylene glycol,4arm/8arm-PLA-PEG from ruixi Multiarm block copolymers 4arm/8arm-PLA-PEG. .The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid.	price>
RY-C-0817	mPEG-SS-NH2	Polymer micelles are a kind of nanoparticles with unique core-shell structure formed by self-assembly of amphiphilic polymers in selective solvents.They are commonly used as self-contained drug carriers.	price>
R-DS-0062	DSPE-PEG-TR	The active and passive DSPE-PEG micelles containing coumarin-6 were constructed by linking tr peptide with DSPE-PEG.After that,we separated glioma stem cells by fluorescence activated immune cell sorting method and tumor ball culture method. By confocal microscopy and flow cytometry,the uptake of TR modified micelles by tumor stem cells was increased,which proved that tr modified micelles were targeted in vitro.	price>
R-R-1156	SEW2871 CAS No.256414-75-2	SEW2871/CAS No.256414-75-2 is an orally active, potent, highly selective S1P1 (sphingosine-1-phosphate type 1 receptor) agonist, with an EC50 of 13.8 nM. SEW2871 activates ERK, Akt, and Rac signaling pathways and induces S1P1 internalization and recycling. SEW2871 reduces lymphocyte numbers in blood.	price>
R-PL-0118	PLA-PEG-CHEMS	Poly(D,L-lactide)-polyethylene glycol-CHEMS, PLA-PEG-CHEMS from ruixi Poly(D,L-lactide)-polyethylene glycol-CHEMS (PLA-PEG-CHEMS) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery.	price>
R-DS-0063	DSPE-PEG-VAP	As a somatostatin analogue,VAP is used as a modifier of tumor targeting delivery system because of its high affinity with somatostatin receptor.Dspe-peg-vap was prepared by chemical coupling of α-NH2 of D-phenylalanine with nhs-pegdspe, and then modified paclitaxel loaded nano micelle delivery system with dspe-peg-vap.	price>
R-R-1157	PI3K/Akt/CREB activator 1 CAS No.2708177-73-3	PI3K/Akt/CREB activator 1 (compound AE-18)/CAS No.2708177-73-3 is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. PI3K/Akt/CREB activator 1 can be used in research of vascular dementia (VaD).	price>

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