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Catalog | name | Description | price |
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R-DS-0048 | DSPE-PEG-NGR(ASP-Gly-Arg)-CD13 | Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery.Polyethylene glycol phosphowax can significantly improve the blood circulation time and stabilize the drug package. These materials can also be used for targeted drug delivery by modifying surface ligands such as antibodies and peptides.The targeting peptide can target CD13 receptor which is over expressed in tumor neovascularization epithelial cells. | price> |
R-R-1142 | CCT365623 hydrochloride CAS No.2126136-98-7 | CCT365623 hydrochloride/CAS No.2126136-98-7 is an orally active lysyl oxidase (LOX) inhibitor, with an IC50 of 0.89 μM. CCT365623 hydrochloride suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF. CCT365623 hydrochloride is extremely well tolerated, and has good pharmacokinetic properties. | price> |
R-PL-0104 | PCL-PEG-NPC | poly(ε-caprolactone)-polyethylene glycol--Nitrophenyl Carbonates PCL-PEG-NPC from ruixi poly(ε-caprolactone)-polyethylene glycol--Nitrophenyl Carbonates (PCL-PEG-NPC) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. | price> |
R-I-009 | ptbua-p4vp | Tert butyl acrylate(tert butyl acrylate)is an important organic ester.It is a colorless and transparent liquid at room temperature.It has good chemical and physical properties such as weather resistance,water resistance,oil resistance and chemical resistance.Polyvinyl pyridine can be used as paper reinforcing agent,fiber modifier,rubber modifier and raw material of ion exchange resin. | price> |
R-DS-0049 | DSPE-PEG-FAL | Non lysosomal cationic liposomes modify common cationic liposomes by introducing special fal peptides.Firstly,the product dspe-pec-fal was obtained by modifying dspe-peg-nh2 with fl polypeptide.The results of NMR and IR showed that the Al peptide was successfully connected to dspe-pec.Cationic lipid 2-dioleoylhydropropyl-3-n,N,k-trimethylammonium (DOTAP) was selected as cationic lipid,Liposomes modified by fal were prepared by film dispersion method using neutral auxiliary lipid dioleoyl phosphatidylethanolamine (DOPE) and the mixture of DSPE-PEC-NH2 and DSPE-PEG-FAL. | price> |
R-R-1143 | Ipatasertib dihydrochloride CAS No.1396257-94-5 | Ipatasertib dihydrochloride (GDC-0068 dihydrochloride)/CAS No.1396257-94-5 is a highly selective and ATP-competitive pan-Akt inhibitor with IC50s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively. | price> |
R-PL-0105 | PCL-PEG-DBCO | poly(ε-caprolactone)-polyethylene glycol--DBCO,PCL-PEG-DBCO from ruixi poly(ε-caprolactone)-polyethylene glycol--DBCO (PCL-PEG-Aminooxy) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. | price> |
R-T-890 | P2VP-PMMA | Polyvinyl pyridine can be used as paper reinforcing agent,fiber modifier,rubber modifier and raw material of ion exchange resin.Poly (methyl methacrylate)(PMMA),with the advantages of high transparency,low price and easy machining,is often used as a substitute for glass. | price> |
R-DS-0050 | DSPE-PEG2000-D4 | Peptide ligands containing six amino acids were screened for tumor cell epidermal growth factor (EGFR).Fluorescent liposomes containing D4 peptide were injected into tumor bearing mice via tail vein.In vivo imaging of small animals showed that fluorescent liposomes not only accumulated in tumor,but also had strong fluorescence signal in brain.Using loperamide as the"probe"and DSPE-PEG2000-D4 micelles as carriers,we found that D4 peptide has the ability to cross the blood-brain barrier through hot water bath tail contraction and formalin induced pain in mice. | price> |
R-R-1144 | Pifusertib hydrochloride CAS No.2930090-28-9 | Pifusertib (TAS-117) hydrochloride/CAS No.2930090-28-9 is a potent, selective, orally active allosteric Akt inhibitor (with IC50s of 4.8, 1.6, and 44 nM for Akt1, 2, and 3, respectively). Pifusertib hydrochloride triggers anti-myeloma activities and enhances fatal endoplasmic reticulum (ER) stress induced by proteasome inhibition. Pifusertib hydrochloride induces apoptosis and autophagy. | price> |
R-PL-0106 | PCL-PEG-TCO | poly(ε-caprolactone)-polyethylene glycol--TCO PCL-PEG-TCO from ruixi poly(ε-caprolactone)-polyethylene glycol--TCO (PCL-PEG-TCO) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. | price> |
R-U-678 | p2vp-ps-pmma | Polystyrene(PS)is a kind of polymer synthesized by free radical addition polymerization of styrene monomer.Polyvinyl pyridine can be used as paper reinforcing agent,fiber modifier,rubber modifier and raw material of ion exchange resin.Poly (methyl methacrylate)(PMMA),with the advantages of high transparency,low price and easy machining,is often used as a substitute for glass. | price> |
R-DS-0051 | DSPE-PEG2000-RLT | Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs. | price> |
R-R-1145 | Paris saponin VII CAS No.68124-04-9 | Paris saponin VII (Chonglou Saponin VII)/CAS No.68124-04-9 is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia. | price> |
R-PL-0107 | PCL-PEG-TZ | poly(ε-caprolactone)-polyethylene glycol--Tetrazine PCL-PEG-TZ from ruixi poly(ε-caprolactone)-polyethylene glycol--Tetrazine (PCL-PEG-TZ) is a linear A-B-C type amphiphilic triblock copolymers. It can be used in preparation of hydrogel for drug encapsulation and drug delivery. | price> |
R-R-2020 | m-peg16-acid | The PEG derivatives and small molecule PEG derivatives provided by Ruixi biology are the products synthesized by our own laboratory,with a complete range of products.Can customize a variety of products. | price> |
R-DS-0052 | DSPE-PEG5000-LTV | On the basis of PL(ID)NP nanoparticles,pl(V/D) np-ltv,a dual-mode CT/fluorescence nanoparticles targeting spontaneous breast cancer,was developed.HER2 targeted nanoparticles pl(I/D) np-ltv were prepared by modifying pl(I/D) NP with targeted phospholipid dspe-peg5000-ltv.The particle size of DLS was 64.9 ± 1.3 nm and had good serum stability. | price> |
R-R-1146 | CHPG sodium salt CAS No.1303993-73-8 | CHPG sodium salt is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. CHPG sodium salt protects against traumatic brain injury (TBI) in vitro and in vivo by activation of the ERK and Akt signaling pathways. | price> |
R-PL-0108 | 4arm/8arm-PCL-PEG | 4arm/8arm poly(ε-caprolactone)-polyethylene glycol,4arm/8arm-PCL-PEG from ruixi Multiarm block copolymers 4arm/8arm-PCL-PEG. .The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid. | price> |
R-DS-0053 | RPAKPAR-PEG-DSPE | A variety of receptors are highly expressed in brain tumor cells and blood-brain barrier,such as transferrin receptor,low-density lipoprotein receptor and so on. Therefore,the specific ligands of these receptors can be used as two-level target molecules for blood-brain barrier and brain tumor cells. | price> |