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R-XASYS-00390 Ligustrazine (hydrochloride),cas:76494-51-4 Ligustrazine(C8H12N2•XHCl,136.2) is a compound that has been found in L. wallichii and has diverse biological activities, including antioxidant, anti-inflammatory, neuroprotective, and anticancer properties.It inhibits hydrogen peroxide-induced decreases in cell viability and the levels of superoxide dismutase (SOD) and glutathione peroxidase (GPX) and increases in reactive oxygen species (ROS) and malondialdehyde (MDA) levels in human umbilical vein endothelial cells (HUVECs) when used at concentrations of 100 and 150 μg/ml. price>
R-R-0390 Cyclo(Phe-Phe) Cyclo(Phe-Phe)/Cyclo(-Phe-Phe)/Cyclo(L-Phe-L-Phe)/Cas.2862-51-3 is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development. price>
R-Z-130 Tocopherol-PEG-NHS Tocopherol-polyethylene glycol-N-hydroxylsuccinimide,Tocopherol-PEG-NHS from ruixi.N-hydroxysuccinimide,white to nearly white crystal,is used in the synthesis of amino acid protectants,semi synthetic kanamycin and pharmaceutical intermediates. price>
R-XASYS-00391 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine,cas:105650-23-5 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)(C13H12N4,224.3) is a food-derived carcinogen that is found in high temperature-cooked fish and meat.In humans, PhIP is metabolized by the cytochrome (CYP) P450 isoform CYP1A2 and conjugated by N-acetyltransferase or sulfotransferase to a metabolite that reacts with DNA to form adducts, which are directly correlated with increased risk of breast, colon, and prostate cancers. price>
R-R-0391 Cyclo(D-Leu-D-Pro) Cyclo(D-Leu-D-Pro)/Cyclo(-D-Leu-D-Pro)/Cas.274680-11-4 is a cyclic dipeptide that is gaining increasing attention in the scientific community due to its potential applications in various areas of research. It has been studied for its biochemical and physiological effects, and its potential to be used in laboratory experiments. This paper will discuss the synthesis method, scientific research applications, mechanism of action, biochemical and physiological effects, advantages and limitations for lab experiments, and future directions of Cyclo(-D-Leu-D-Pro). price>
R-Z-131 Tocopherol-PEG-BIOTIN Tocopherol-polyethylene glycol-Biotin,Tocopherol-PEG-BIOTIN from ruixi.Biotin, also known as vitamin H and coenzyme R,is the coenzyme of various carboxylase, which plays the role of CO2 carrier in the carboxylase reaction. price>
R-XASYS-00392 Fenretinide-d4,cas:2118244-64-5 Fenretinide(C26H29D4NO2,395.6) is intended for use as an internal standard for the quantification of fenretinide by GC- or LC-MS. Fenretinide is a synthetic derivative of retinoic acid and an inhibitor of dihydroceramide desaturase (IC50 = 2.32 µM).It promotes the generation of reactive oxygen species (ROS), the degradation of anti-apoptotic MCL-1, and the cleavage of pro-apoptotic PKCδ. price>
R-R-0392 Cyclo(His-Phe) Cyclo(His-Phe)/Cyclo(-His-Phe)/CAS:56586-95-9 from ruixi. Catalyst for asymmetric cyanohydrin synthesis. The addition of hydrogen cyanide to benzaldehyde gives the highest optical yield ever obtained for the corresponding cyanohydrin. In a study of McCleland et al., Cyclo(His-Phe) showed significant anti-tumour activity, causing reduction of cell viability in cervical cancer cells. In isolated rat hearts, the diketopiperazine caused a gradual reduction of heart rate and a decrease in coronary flow rate. price>
R-Z-132 Tocopherol-PEG-SH Tocopherol-polyethylene glycol-Thiol,Tocopherol-PEG-SH from ruixi.Tocopherol-PEG-SH is a linear heterobifunctional peg reagent with thiol and tocopherol. price>
R-XASYS-00393 Kaempferol-3-glucoside,cas:480-10-4 Kaempferol-3-glucoside(C21H20O11,448.4) is an orally bioavailable flavonoid that has been isolated from the leaves of D. kaki and R. agrestis and has anti-inflammatory activity.Kaempferol-3-glucoside (20-80 µg/ml) dose-dependently inhibits IL-1β-stimulated nitric oxide and prostaglandin E2 (PGE2) production in patient-derived osteoarthritis chondrocytes, an effect that is blocked by the PPAR-γ inhibitor GW 9662. price>
R-R-0393 Cyclo(Gly-Ser) Cyclo(Gly-Ser)/Cyclo(-Gly-Ser)/Cyclo(glycyl-L-seryl)/Cas.52661-98-0 is a cyclic dipeptide formed by the cyclization of the amino acid sequence Glycine (Gly) and Serine (Ser). The specific properties and potential applications of Cyclo(Gly-Ser) would depend on its structure and the context in which it is studied. It may be of interest for research in the areas of peptide-based drug design, bioactive compound development, or other biomedical applications. Cyclo(Gly-Ser) has been shown to exhibit some antimicrobial activity and could potentially be explored further for this purpose. price>
R-Z-133 Tocopherol-PEG-N3 Tocopherol-polyethylene glycol-azide,Tocopherol-PEG-N3 from ruixi.Tocopherol-PEG-N3 is a linear heterobifunctional peg reagent with Tocopherol and azide group. price>
R-XASYS-00394 Decursin,cas:5928-25-6 Decursin(C19H20O5,328.4) is a phytochemical originally isolated from A. gigas with diverse biological activities.It reduces the growth of B16/F10 murine melanoma cells, but not NIH-3T3 fibroblasts, via induction of apoptosis and increased caspase-3 activity when used at concentrations ranging from 40 to 100 μM. price>
R-R-0394 Cyclo(Gly-His) Cyclo(Gly-His)/Cyclo(-Gly-His)/Cyclo(-Gly-L-His)/Cas.15266-88-3 is a cyclopeptide antibiotic. It is the most potent cyclic peptide antibiotic in terms of metal ion binding affinity, with the ability to bind to divalent metal ions such as Mg2+, Ca2+, Cu2+, Zn2+, and Mn2+. Cyclo(-Gly-L-His) binds to these ions by undergoing a chelate complex formation. The thermodynamic parameters for this interaction are constants that depend on the type of metal ion. The complex formation between cyclo(-Gly-L-His) and divalent metal ions has been shown to be important in determining the inhibition of enzymes such as DNA gyrase and topoisomerase IV. price>
R-Z-134 Tocopherol-PEG-alkyne(ALK) Tocopherol-polyethylene glycol-alkyne,Tocopherol-PEG-alkyne(ALK)from ruixi.Ruixi is a biotechnology company.Our company focuses on the production and sales of scientific research level drug delivery and drug nano targeting products.At present,our products mainly include synthetic phospholipids, PEG derivatives,block copolymers,nano gold,magnetic nanoparticles,mesoporous silica,reactive fluorescent dyes,fluorescent quantum dots,click chemistry and macrocyclic ligands. price>
R-XASYS-00395 Umbelliferone,cas:93-35-6 Umbelliferone(C9H6O3,162.1) is a naturally occurring derivative and metabolite of coumarin that has diverse biological activities including antitumor and antidepressant-like properties.It inhibits the growth of a variety of human cell lines, including human ACHN renal, A549 lung, HCT15 colon, and LNCaP prostate carcinoma as well as Dakiki myeloma and HL-60 lymphoma cells, when used at concentrations ranging from 250 to 300 µg/ml. price>
R-R-0395 Cyclo(Glu-Gly) Cyclo(Glu-Gly)/Cyclo(-Gly-L-Glu)/Cyclo(-Glu-Gly)/CAS 16364-35-5 is a cyclic dipeptide that has been analyzed using LC-MS/MS. It is a bioactive compound that can be found in the bioscience and biochemistry fields. Cyclo(-Gly-L-Glu) is used as an analytical method for determining the presence of dipeptides, which are small molecules composed of two amino acids linked together by a peptide bond. The cyclic form of the molecule allows it to bind to proteins and other molecules in order to stabilize them. Cyclo(-Gly-L-Glu) has also been shown to have potential as a therapeutic agent for cancer treatments, based on its ability to inhibit the activity of protein kinases involved in cell proliferation and apoptosis. price>
R-Z-135 Tocopherol-PEG-folate Tocopherol-polyethylene glycol-folate,Tocopherol-PEG-folate from ruixi.Ruixi is a biotechnology company.Our company focuses on the production and sales of scientific research level drug delivery and drug nano targeting products. At present,our products mainly include synthetic phospholipids,PEG derivatives, block copolymers, nano gold,magnetic nanoparticles, mesoporous silica,reactive fluorescent dyes,fluorescent quantum dots,click chemistry and macrocyclic ligands. price>
R-XASYS-00396 Aucubin,cas:479-98-1 Aucubin(C15H22O9,346.3) is an iridoid glycoside that has been found in E. ulmoides with diverse biological activities.Aucubin (0.001-1μg/ml) dose-dependently inhibits the IgE-stimulated secretion of IL-6 and TNF-αby RBL-2H3 mast cells (IC50s = 0.19 and 0.1μg/ml, respectively). price>
R-R-0396 Cyclo(Gln-Gly) Cyclo(Gln-Gly)/Cyclo(-Gln-Gly)/Cyclo(Gly-L-Gln)/Cas.52662-00-7 is an endogenous compound related to the cyclic peptide family, which includes neuropeptides such as β-endorphin. Cyclo(Gly-L-Gln) has been found to increase intracerebroventricular (i.c.v.) levels of β-endorphin and dopamine in rats, leading to a depression recovery response. The molecule has dose-dependent effects on the opioid receptor, with low doses acting as an agonist and high doses acting as an antagonist. This drug is also not polar and has a conformation that is similar to nicotine, which may explain its addictive properties and ability to induce dependence. price>