Cyclo(Gln-Gly)

Cyclo(Gln-Gly)/Cyclo(-Gln-Gly)/Cyclo(Gly-L-Gln)/Cas.52662-00-7 is an endogenous compound related to the cyclic peptide family, which includes neuropeptides such as β-endorphin. Cyclo(Gly-L-Gln) has been found to increase intracerebroventricular (i.c.v.) levels of β-endorphin and dopamine in rats, leading to a depression recovery response. The molecule has dose-dependent effects on the opioid receptor, with low doses acting as an agonist and high doses acting as an antagonist. This drug is also not polar and has a conformation that is similar to nicotine, which may explain its addictive properties and ability to induce dependence.

msds of Cyclo(Gln-Gly)