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R-R-0310 DOTA-RGD DOTA-RGD is a radiolabeled peptide-based compound used in molecular imaging and targeted therapy.DOTA-RGD can also be used for targeted therapy by attaching therapeutic isotopes, such as Lutetium-177, to the RGD peptide. This enables the delivery of localized radiation to tumors with high integrin receptor expression, potentially leading to the destruction of cancer cells. price>
R-XASYS-00311 5-fluoro 203,cas:260443-89-8 5-fluoro 203(C14H11FN2S,258.3) is a cytotoxic compound that at 1 µM activates AhR signaling, inducing transcription of CYP1A1, which leads to the formation of DNA adducts and cell cycle arrest.In certain ovarian, breast, kidney, and colorectal cancer cells, 5-fluoro 203 can increase the levels of reactive oxygen species as well as activate JNK, ERK, and p38 MAPK. price>
R-R-0311 DOTA-JR-11 DOTA-JR11 is a somatostatin receptor 2(SSTR2)antagonist. DOTA-JR11 can be labeled by 68Ga, used for paired imaging in neuroendocrine tumors (NETs) research. price>
R-XASYS-00312 α-Boswellic Acid,cas:471-66-9 α-Boswellic acid(C30H48O3,456.7) is a pentacyclic triterpene and an isomer of β-boswellic acid originally isolated from B. serrata.It increases Survivin and Reelin expression, decreases production of reactive oxygen species (ROS) and levels of hyperphosphorylated Tau price>
R-R-0312 DOTA-Glu[cyclo(Arg-Gly-Asp-D-Phe-Lys)]2 DOTA-Glu[cyclo(Arg-Gly-Asp-D-Phe-Lys)]2, also known as DOTA-E[c(RGDfK)]2, is a radiolabeled peptide-based compound used in molecular imaging and targeted therapy. It is a specific molecule designed to target integrin receptors, which are proteins found on the surface of cells, often overexpressed in tumors and involved in processes such as tumor growth, angiogenesis, and metastasis. price>
R-XASYS-00313 Cytochalasin H,cas:53760-19-3 The cytochalasins(C30H39NO5,493.6) are cell-permeable fungal metabolites that inhibit actin polymerization.This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. price>
R-R-0313 NOTA-E(cRGDfK)2 NOTA-E(cRGDfK)2 is a radiolabeled peptide-based compound used in molecular imaging and targeted therapy, with a specific focus on targeting integrin receptors commonly found in cancer cells. The compound consists of a cyclic peptide motif, cRGDfK, which possesses high affinity for integrin receptors, along with a chelator called NOTA (1,4,7-triazacyclononane-1,4,7-triacetic acid) that allows for the complexation of radioactive metals. price>
R-XASYS-00314 Erythrodiol,cas:545-48-2 Erythrodiol(C30H50O2,442.7) is a triterpene that has been found in olive oil and has diverse biological activities.It induces relaxation of isolated rat aortic rings precontracted with phenylephrine (EC50 = 3.38 µM).Erythrodiol inhibits the growth of HT-29 adenocarcinoma cells (EC50 = 48.8 µM). price>
R-R-0314 Galacto-RGD Galacto-RGD/CAS.922175-70-0 is a specialized peptide that was first isolated from the laminin in the extracellular matrix of various tissues. The -RGD sequence in the name stands for the tripeptide sequence: Arginine-Glycine-Aspartic acid. This sequence is present in numerous extracellular matrix proteins, including laminin, vitronectin, and fibronectin. Together with the galactose moiety, Galacto-RGD acts as a potent inhibitor for attaching integrins, which play a crucial role in activating cell adhesion signals. price>
R-XASYS-00315 B355252,cas:1261576-81-1 B355252(C25H24ClN3O3S2,514.1) is a neuroprotective agent.It potentiates NGF-induced neurite outgrowth in NS-1 cells (EC50 = ~1 μM).B355252 inhibits glutamate-induced excitotoxicity in HT-22 cells in a concentration-dependent manner and inhibits glutamate-induced decreases in GSH levels and increases in Bax levels price>
R-R-0315 [18F]FB-RGD [18F]FB-RGD is a radiolabeled compound used in molecular imaging and targeted therapy, particularly in the field of cancer imaging and oncology research. [18F]FB-RGD can potentially be used in targeted therapy by attaching therapeutic agents or radioisotopes to the RGD peptide, enabling the specific delivery of treatment to tumors with high integrin receptor expression. price>
R-XASYS-00316 α-Cyperone,cas:473-08-5 α-Cyperone(C15H22O,218.3) is a sesquiterpenoid that has been found in C. rotundus rhizomes and has diverse biological activities.It inhibits LPS-induced nuclear translocation of the NF-κB subunit p65, as well as LPS-induced production of prostaglandin E2 (PGE2;) and IL-6, in RAW 264.7 cells. price>
R-R-0316 NOTA-P2-RM26 NOTA-P2-RM26 is a peptide-based compound used in molecular imaging and targeted therapy for prostate cancer. NOTA-P2-RM26 represents a promising tool for the molecular imaging and targeted therapy of prostate cancer, offering potential applications in diagnosis, staging, and personalized treatment of this disease. price>
R-XASYS-00317 Kaempferol 3-glucuronide,cas:22688-78-4 Kaempferol 3-glucuronide(C21H18O12,462.4) is a flavonol glycoside that has been found in Fragaria and an active metabolite of kaempferol that has diverse biological activities.It is formed from kaempferol primarily in the small intestine. price>
R-R-0317 (68Ga)Nota-prgd2 (68Ga)NOTA-PRGD2/CAS:1345968-02-6 is a radiolabeled compound used in molecular imaging and targeted therapy for cancer.In addition to its imaging applications, (68Ga)NOTA-PRGD2 can also be explored for targeted therapy. For example, therapeutic agents or radioisotopes can be attached to the peptide sequence, potentially allowing for the specific delivery of treatment to cancer cells expressing high levels of integrin receptors. price>
R-XASYS-00318 Yatein,cas:40456-50-6 Yatein(C22H24O7,400.4) is a lignan that has been found in C. formosana and has diverse biological activities.It inhibits the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 1 μM).Yatein inhibits herpes simplex virus (HSV-1) replication in a plaque reduction assay (IC50 = 30.6 μM). price>
R-R-0318 NOTA-WL12 NOTA-WL12 is a chelator-peptide conjugate, which can be used in molecular imaging and targeted therapy.NOTA-WL12 can potentially be used in targeted therapy. By attaching therapeutic agents or radioisotopes to the WL12 peptide, it can be used to deliver treatment specifically to the cells or tissues expressing the target protein or receptor, potentially enhancing the efficacy of the treatment and reducing side effects. price>
R-XASYS-00319 Methylophiopogonanone B,cas:74805-91-7 Methylophiopogonanone B(C19H20O5,328.4) is an isoflavone that has been found in O. japonicus and has diverse biological activities.It increases Rho activity in normal human epidermal melanocytes (NHEMs) when used at a concentration of 1 µM. price>
R-R-0319 Dota-ggga Dota-ggga, also known as D-ggga CAS:149206-86-0, is a chemical compound that has recently gained attention in the scientific community due to its potential therapeutic applications. This compound has been found to have a unique mechanism of action that makes it a promising candidate for the treatment of various diseases. price>
R-XASYS-00320 Cardanol monoene,cas:501-26-8 Cardanol monoene(C21H34O,302.5) is a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 56 µM in vitro.It halts the cell cycle at the S phase and inhibits proliferation dose- and time-dependently in M14 melanoma cells (IC50s = 23.15 and 12.30 µM after 24 and 48 hours of treatment, respectively). price>