XL019 CAS:945755-56-6
XL019
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-C-659 | 10mg | 135.00 | + Add to cart |
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R-C-659 | 50mg | 225.00 | + Add to cart |
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R-C-659 | 100mg | 675.00 | + Add to cart |
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Product description
XL019 is a potent,orally active,and selective JAK2 inhibitor,with IC50s of 2.2,134.3,and 214.2 nM for JAK2,JAK1 and JAK3,respectively.XL019 shows 50-fold or greater selectivity for JAK2,versus a panel of over 100 serine/threonine and tyrosine kinases,including other members of the JAK family.XL019 potently inhibits STAT3 and STAT5 phosphorylation in cells harboring either JAK2V617F or wild-type JAK2.
Appearance | N/A |
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Molecular Weight | N/A |
Purity | >95% |
PDI by GPC | <1.5 |
Solubility | DMSO |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
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