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XL019 CAS:945755-56-6

XL019

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-C-659 10mg 135.00
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R-C-659 50mg 225.00
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R-C-659 100mg 675.00
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Product description

XL019 is a potent,orally active,and selective JAK2 inhibitor,with IC50s of 2.2,134.3,and 214.2 nM for JAK2,JAK1 and JAK3,respectively.XL019 shows 50-fold or greater selectivity for JAK2,versus a panel of over 100 serine/threonine and tyrosine kinases,including other members of the JAK family.XL019 potently inhibits STAT3 and STAT5 phosphorylation in cells harboring either JAK2V617F or wild-type JAK2.

XL019     CAS:945755-56-6

Appearance N/A
Molecular Weight N/A
Purity >95%
PDI by GPC <1.5
Solubility DMSO
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
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