WP1066 CAS:857064-38-1

WP1066 is a Stat3 inhibitor and JAK2 inhibitor.WP1066 is also a novel analogue of the JAK2 inhibitor AG490,in JAK2 V617F-positive erythroleukemia HEL cells and in blood cells from patients with polycythemia vera.WP1066 significantly inhibited JAK2 and its downstream signal transducer and activator of transcription-3,signal transducer and activator of transcription-5,and extracellular signal-regulated kinase-1/2 pathways in a dose-and time-dependent manner. 

msds---WP1066