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VU0364770 hydrochloride CAS No.1414842-70-8
VU0364770 hydrochloride CAS No.1414842-70-8
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-2745 | 50mg | 190.00 | + Add to cart |
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| R-R-2745 | 100mg | 310.00 | + Add to cart |
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Product description
VU0364770 hydrochloride/CAS No.1414842-70-8 is a selective and potent positive allosteric modulator (PAM) of mGlu4. VU0346770 hydrochloride exhibits EC50s of 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor, respectively. VU0364770 hydrochloride exhibits antagonist activity at mGlu5 with a potency of 17.9 μM and PAM activity at mGlu6 with a potency of 6.8 μM. VU0364770 hydrochloride also possesses activity at MAO with Ki values of 8.5 and 0.72 μM for human MAO-A and human MAO-B, respectively.
| Appearance | N/A |
|---|---|
| Molecular Weight | 269.13 |
| Purity | >90% |
| CAS | 1414842-70-8 |
| Formula | C12H10Cl2N2O |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
Document
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