Verdinexor (KPT-335) CAS: 1392136-43-4
Verdinexor (KPT-335)
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-C-1416 | 50mg | 425.00 | + Add to cart |
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R-C-1416 | 100mg | 700.00 | + Add to cart |
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R-C-1416 | 200mg | 1220.00 | + Add to cart |
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Product description
Verdinexor(KPT-335)is an orally bioavailable Selective Inhibitor of Nuclear Export(SINE).KPT-335 inhibited proliferation,blocked colony formation,and induced apoptosis of treated cells at biologically relevant concentrations of drug.Additionally,KPT-335 downregulated XPO1 protein while inducing a concomitant increase in XPO1 messenger RNA.KPT-335 treatment of cell lines upregulated the expression of both protein and mRNA for the tumor suppressor proteins p53 and p21,and promoted their nuclear localization.
Appearance | N/A |
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Molecular Weight | N/A |
purity | >95% |
PDI by GPC | <1.5 |
Solubility | N/A |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
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