Vercirnon CAS No.698394-73-9
Vercirnon CAS No.698394-73-9
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
---|---|---|---|---|
R-R-4175 | 5mg | 360.00 | + Add to cart |
|
R-R-4175 | 10mg | 560.00 | + Add to cart |
|
|
Product description
Vercirnon (GSK1605786A)/CAS No.698394-73-9 is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 µM for all). Vercirnon is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively.
Appearance | N/A |
---|---|
Molecular Weight | 444.93 |
Purity | >90% |
CAS | 698394-73-9 |
Formula | C22H21ClN2O4S |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
Document
Related Product