URMC-099 CAS：1229582-33-5

URMC-099 is an orally bioavailable,brain penetrant mixed lineage kinase (MLK)inhibitor with IC50 of 19 nM,42 nM,14 nM,and 150 nM,for MLK1,MLK2,MLK3,and DLK,respectively,and also inhibits LRRK2 activity with IC50 of 11 nM.URMC-099 also inhibits ABL1 with IC50 of 6.8 nM.URMC-099 induces autophagy.

msds---URMC-099