Ulixertinib (BVD-523) CAS No. 869886-67-9

Ulixertinib is an orally available inhibitor of extracellular signal-regulated kinase(ERK)1 and 2,with potential antineoplastic activity.Upon oral administration,ulixertinib inhibits both ERK 1 and 2,thereby preventing the activation of ERK-mediated signal transduction pathways.This results in the inhibition of ERK-dependent tumor cell proliferation and survival.The mitogen-activated protein kinase(MAPK)/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.

msds---Ulixertinib (BVD-523)