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Tyk2-IN-7 CAS No.1609391-90-3
Tyk2-IN-7 CAS No.1609391-90-3
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-2314 | 5mg | 450.00 | + Add to cart |
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| R-R-2314 | 10mg | 800.00 | + Add to cart |
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Product description
Tyk2-IN-7/CAS No.1609391-90-3 is a TYK2 JH2 inhibitor, binds to TYK2 JH2 domain with IC50 and Ki.app of 0.00053 μM and 0.00007 μM, respectively. Tyk2-IN-7 provides a highly selective alternative to conventional TYK2 orthosteric inhibitors, inhibits TYK2/JAK1/JAK2 kinase domain. Tyk2-IN-7 provides robust inhibition in a mouse IL-12-induced IFNγ pharmacodynamic model as well as efficacy in an IL-23 and IL-12-dependent mouse colitis model.
| Appearance | N/A |
|---|---|
| Molecular Weight | 401.46 |
| Purity | >90% |
| CAS | 1609391-90-3 |
| Formula | C18H15D3N6O3S |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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