Trovafloxacin CAS：147059-72-1

Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive,Gram-negative and anaerobic organisms.Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity.Trovafloxacin is also a potent,selective and orally active pannexin 1 channel(PANX1)inhibitor with an IC50 of 4 μM for PANX1 inward current.Trovafloxacin does not inhibit connexin 43 gap junction or PANX2.Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1.

msds---Trovafloxacin