Ticagrelor (AZD6140) CAS:274693-27-5

Ticagrelor is a reversible antagonist of the platelet purinergic P2Y12 receptor (Ki=14 nM;IC50=1.8μM),which is the main receptor responsible for ADP-induced platelet aggregation.1,2It functions by directly changing the conformation of the P2Y12 receptor to inhibit ADP binding.3Formulations containing ticagrelor have been used to reduce the rate of thrombotic cardiovascular events in patients with acute coronary syndrome.

msds---Ticagrelor (AZD6140)