Tetrazine-Cyanine5

The fluorescent dye Cy5 tetrazine is a fluorescent dye produced by Ruixi biological. Tetrazine trans cyclooctene(TCO)linkage is a nontoxic biomarker method.Tetrazine functionalized molecules react with TCO functionalized molecules to form stable conjugates through dihydropyrazine.This reverse electron demand cycloaddition reaction has been widely used because TCO,as a diene, may have very fast cycloaddition kinetics.Cy5 tetrazine has been used to label biomolecules for fluorescence imaging and other fluorescence based biochemical analysis.It is widely used to label peptides,proteins and oligonucleotides.

msds---Tetrazine-Cyanine5