SYVN1 Peptide
synovial apoptosis inhibitor 1 Peptide
Product description
Synoviolin (SYVN1) acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates subsequently promoting their degradation. For instance, SYVN1 protects neurons from apoptosis induced by polyglutamine-expanded huntingtin (HTT) or unfolded GPR37 by promoting their degradation. SYVN1 is up-regulated in synovial tissues from patients with rheumatoid arthritis.
Appearance | N/A |
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Molecular weight | N/A |
Purity | >90% |
Solubility | N/A |
Sequence | HERQHLEARLQS |
Molecular Formula | C81H130N24O34S2 |
Synonyms | E3 ubiquitin-protein ligase synoviolin; Synovial apoptosis inhibitor 1; HRD1; SYVN1, synoviolin 1 |
Storage | -20℃,protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
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