Selumetinib(AZD6244) CAS:606143-52-6
Selumetinib(AZD6244)
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-C-450 | 100mg | 147.00 | + Add to cart |
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R-C-450 | 200mg | 210.00 | + Add to cart |
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R-C-450 | 500mg | 420.00 | + Add to cart |
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Product description
Selumetinib(AZD6244,ARRY-142886) is a potent, highly selective MEK inhibitor with IC50 of 14 nM for MEK1 and Kd value of 530 nM for MEK2.It also inhibits ERK1/2 phosphorylation with IC50 of 10 nM,no inhibition to p38α,MKK6,EGFR,ErbB2, ERK2,B-Raf,etc.Selumetinib suppresses cell proliferation,migration and trigger apoptosis.
Appearance | N/A |
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Molecular Weight | N/A |
Purity | >95% |
PDI by GPC | <1.5 |
Solubility | Organic solvents |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
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