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Selumetinib(AZD6244) CAS:606143-52-6

Selumetinib(AZD6244)

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-C-450 100mg 147.00
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R-C-450 200mg 210.00
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R-C-450 500mg 420.00
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Product description

Selumetinib(AZD6244,ARRY-142886) is a potent, highly selective MEK inhibitor with IC50 of 14 nM for MEK1 and Kd value of 530 nM for MEK2.It also inhibits ERK1/2 phosphorylation with IC50 of 10 nM,no inhibition to p38α,MKK6,EGFR,ErbB2, ERK2,B-Raf,etc.Selumetinib suppresses cell proliferation,migration and trigger apoptosis.


Appearance N/A
Molecular Weight N/A
Purity >95%
PDI by GPC <1.5
Solubility Organic solvents
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
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