SC66 CAS：871361-88-5

SC66 is a novel and potent AKT inhibitor,which reduced cell viability in a dose- and time-dependent manner,inhibited colony formation and induced apoptosis in HCC cells.SC66 treatment led to a reduction in total and phospho-AKT levels. SC66 significantly potentiated the effects of both conventional chemotherapeutic and targeted agents,doxorubicin and everolimus,respectively.In vivo,SC66 inhibited tumor growth of Hep3B cells in xenograft models,with a similar mechanism observed in the in vitro model.SC66 had antitumor effects on HCC cells.

msds---SC66