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SAH-SOS1A TFA CAS No.2896737-31-6
SAH-SOS1A TFA CAS No.2896737-31-6
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-3020 | 5mg | 400.00 | + Add to cart |
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| R-R-3020 | 10mg | 680.00 | + Add to cart |
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Product description
SAH-SOS1A TFA/CAS No.2896737-31-6 is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A TFA binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity (EC50=106-175 nM). SAH-SOS1A TFA directly and independently blocks nucleotide association. SAH-SOS1A TFA impairs KRAS-driven cancer cell viability and exerts its effects by on-mechanism blockade of the ERK-MAPK phosphosignaling cascade downstream of KRAS.
| Appearance | N/A |
|---|---|
| Molecular Weight | 2301.55 |
| Purity | >90% |
| CAS | 2896737-31-6 |
| Formula | C102H160N27F3O30 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
Document
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