Rolapitant(sch619734) CAS No. 552292-08-7
Rolapitant(sch619734)
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-C-1043 | 25mg | 220.00 | + Add to cart |
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R-C-1043 | 50mg | 385.00 | + Add to cart |
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R-C-1043 | 100mg | 600.00 | + Add to cart |
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Product description
SCH-619734 is an orally bioavailable,centrally-acting,selective neurokinin 1 receptor(NK1-receptor)antagonist with a Ki of 0.66 nM.Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system,thereby inhibiting the binding of the endogenous ligand,substance P(SP).Rolapitant is active at 0.1 and 1 mg/kg in both acute and delayed emesis models in ferrets,respectively.
Appearance | N/A |
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Molecular Weight | N/A |
purity | >95% |
PDI by GPC | <1.5 |
Solubility | N/A |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
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