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Home > products > apis > neuronal-signaling > rolapitant

Rolapitant(sch619734) CAS No. 552292-08-7

Rolapitant(sch619734)

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-C-1043 25mg 220.00
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R-C-1043 50mg 385.00
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R-C-1043 100mg 600.00
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Product description

SCH-619734 is an orally bioavailable,centrally-acting,selective neurokinin 1 receptor(NK1-receptor)antagonist with a Ki of 0.66 nM.Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system,thereby inhibiting the binding of the endogenous ligand,substance P(SP).Rolapitant is active at 0.1 and 1 mg/kg in both acute and delayed emesis models in ferrets,respectively.


Appearance N/A
Molecular Weight N/A
purity >95%
PDI by GPC <1.5
Solubility N/A
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
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msds---Rolapitant(sch619734)
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