Rhodamine Red-maleimide

Rhodamine red, also known as sulfonated rhodamine B, and lissamine rhodamine B (LRB), is a sulfonated substituted rhodamine B. Its excitation and emission peaks are 570 nm and 590 nm, respectively. The emission spectrum is between tetramethylrhodamine and Texas Red. It is a common fluorescent dye. Similar to Dezhou red, rhodamine red has its own sulfonate ion, which has good water solubility and is conducive to biomarker Maleimide is a group commonly used in biomarker reaction. It can generate stable thioether structure through affinity addition reaction with sulfhydryl (- SH), so as to realize labeling. Although amino groups (such as lysine arginine side chain) also have affinity, maleimide selectively labels sulfhydryl groups in neutral or slightly acidic buffer (reaction speed > 1000 times faster than amino groups). The labeling reaction has the advantages of rapid reaction, high selectivity and good yield. In addition, sulfhydryl is a functional group widely existing in biomolecules, such as serine and disulfide bond in proteins. Therefore, maleimide / thiol labeling has become the most commonly used biological ligation reaction second only to NHS / amino labeling.

msds of Rhodamine Red-maleimide