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R-268712 CAS No.879487-87-3
R-268712 CAS No.879487-87-3
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-2619 | 25mg | 310.00 | + Add to cart |
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| R-R-2619 | 50mg | 500.00 | + Add to cart |
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Product description
R-268712/CAS No.879487-87-3 is an orally active and selective ALK-5 inhibitor, with an IC50 of 2.5 nM. R-268712 inhibits the phosphorylation of Smad3 in a dose-dependent manner with an IC50 of 10.4 nM. R-268712 suppresses glomerulonephritis as well as glomerulosclerosis by inhibiting TGF-β signaling, which can be used in studies of renal fibrosis and cancer.
| Appearance | N/A |
|---|---|
| Molecular Weight | 363.39 |
| Purity | >90% |
| CAS | 879487-87-3 |
| Formula | C20H18FN5O |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
Document
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